The effect of gender on the clinical features and therapeutic response in obsessive-compulsive disorder

Detalhes bibliográficos
Autor(a) principal: Fontenelle,Leonardo
Data de Publicação: 2002
Outros Autores: Marques,Carla, Versiani,Marcio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462002000100005
Resumo: OBJECTIVE: To investigate the existence of clinical and therapeutic differences that could possibly characterize specific subgroups of patients with obsessive-compulsive disorder (OCD) based on their gender. METHODS: Male (n=32) and female patients with OCD (n=37) were compared with regard to age and mode of onset, duration and course of the illness, number of obsessions and compulsions, and subtype of OCD according to the International Classification of Diseases, 10th edition. The groups were also compared with regard to scores on the Yale-Brown Obsessive-Compulsive Scale, Clinical Global Impression, Beck Depression Inventory and Global Assessment of Functioning, before and after drug treatment for 10 weeks. Chi-square test with Yates correction or Fisher's exact test were employed for comparisons between categorical variables and Student's t or Mann-Whitney tests were used to compare continuous variables. The adopted level of significance was 5%. RESULTS: Male patients with OCD were characterized by an earlier age of onset and greater global severity. Furthermore, a trend to display greater number of obsessions and compulsions and worse global functioning was found among male patients, whereas a trend to more severe depressive symptoms was observed in female patients. No significant differences between the groups were found with regard to treatment response. CONCLUSIONS: Our findings suggest that there may be OCD subtypes based on gender.
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spelling The effect of gender on the clinical features and therapeutic response in obsessive-compulsive disorderObsessive-compulsive disorderGenderSexDiagnosis, clinicalOBJECTIVE: To investigate the existence of clinical and therapeutic differences that could possibly characterize specific subgroups of patients with obsessive-compulsive disorder (OCD) based on their gender. METHODS: Male (n=32) and female patients with OCD (n=37) were compared with regard to age and mode of onset, duration and course of the illness, number of obsessions and compulsions, and subtype of OCD according to the International Classification of Diseases, 10th edition. The groups were also compared with regard to scores on the Yale-Brown Obsessive-Compulsive Scale, Clinical Global Impression, Beck Depression Inventory and Global Assessment of Functioning, before and after drug treatment for 10 weeks. Chi-square test with Yates correction or Fisher's exact test were employed for comparisons between categorical variables and Student's t or Mann-Whitney tests were used to compare continuous variables. The adopted level of significance was 5%. RESULTS: Male patients with OCD were characterized by an earlier age of onset and greater global severity. Furthermore, a trend to display greater number of obsessions and compulsions and worse global functioning was found among male patients, whereas a trend to more severe depressive symptoms was observed in female patients. No significant differences between the groups were found with regard to treatment response. CONCLUSIONS: Our findings suggest that there may be OCD subtypes based on gender.Associação Brasileira de Psiquiatria2002-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462002000100005Brazilian Journal of Psychiatry v.24 n.1 2002reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)instname:Associação Brasileira de Psiquiatria (ABP)instacron:ABP10.1590/S1516-44462002000100005info:eu-repo/semantics/openAccessFontenelle,LeonardoMarques,CarlaVersiani,Marcioeng2002-08-23T00:00:00Zoai:scielo:S1516-44462002000100005Revistahttp://www.bjp.org.br/ahead_of_print.asphttps://old.scielo.br/oai/scielo-oai.php||rbp@abpbrasil.org.br1809-452X1516-4446opendoar:2002-08-23T00:00Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)false
dc.title.none.fl_str_mv The effect of gender on the clinical features and therapeutic response in obsessive-compulsive disorder
title The effect of gender on the clinical features and therapeutic response in obsessive-compulsive disorder
spellingShingle The effect of gender on the clinical features and therapeutic response in obsessive-compulsive disorder
Fontenelle,Leonardo
Obsessive-compulsive disorder
Gender
Sex
Diagnosis, clinical
title_short The effect of gender on the clinical features and therapeutic response in obsessive-compulsive disorder
title_full The effect of gender on the clinical features and therapeutic response in obsessive-compulsive disorder
title_fullStr The effect of gender on the clinical features and therapeutic response in obsessive-compulsive disorder
title_full_unstemmed The effect of gender on the clinical features and therapeutic response in obsessive-compulsive disorder
title_sort The effect of gender on the clinical features and therapeutic response in obsessive-compulsive disorder
author Fontenelle,Leonardo
author_facet Fontenelle,Leonardo
Marques,Carla
Versiani,Marcio
author_role author
author2 Marques,Carla
Versiani,Marcio
author2_role author
author
dc.contributor.author.fl_str_mv Fontenelle,Leonardo
Marques,Carla
Versiani,Marcio
dc.subject.por.fl_str_mv Obsessive-compulsive disorder
Gender
Sex
Diagnosis, clinical
topic Obsessive-compulsive disorder
Gender
Sex
Diagnosis, clinical
description OBJECTIVE: To investigate the existence of clinical and therapeutic differences that could possibly characterize specific subgroups of patients with obsessive-compulsive disorder (OCD) based on their gender. METHODS: Male (n=32) and female patients with OCD (n=37) were compared with regard to age and mode of onset, duration and course of the illness, number of obsessions and compulsions, and subtype of OCD according to the International Classification of Diseases, 10th edition. The groups were also compared with regard to scores on the Yale-Brown Obsessive-Compulsive Scale, Clinical Global Impression, Beck Depression Inventory and Global Assessment of Functioning, before and after drug treatment for 10 weeks. Chi-square test with Yates correction or Fisher's exact test were employed for comparisons between categorical variables and Student's t or Mann-Whitney tests were used to compare continuous variables. The adopted level of significance was 5%. RESULTS: Male patients with OCD were characterized by an earlier age of onset and greater global severity. Furthermore, a trend to display greater number of obsessions and compulsions and worse global functioning was found among male patients, whereas a trend to more severe depressive symptoms was observed in female patients. No significant differences between the groups were found with regard to treatment response. CONCLUSIONS: Our findings suggest that there may be OCD subtypes based on gender.
publishDate 2002
dc.date.none.fl_str_mv 2002-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-44462002000100005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
dc.source.none.fl_str_mv Brazilian Journal of Psychiatry v.24 n.1 2002
reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
instname:Associação Brasileira de Psiquiatria (ABP)
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instname_str Associação Brasileira de Psiquiatria (ABP)
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reponame_str Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
collection Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
repository.name.fl_str_mv Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)
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