Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies

Detalhes bibliográficos
Autor(a) principal: Reddy,S. Giridhar
Data de Publicação: 2013
Outros Autores: Pandit,Akanksha Saxena
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Polímeros (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282013000100005
Resumo: In this article, Sodium alginate and Lignosulphonic acid blends were prepared in different weight ratios by solution casting method. Swelling experiments were conducted for Sodium alginate and its blends by adding calcium chloride for various intervals in a pH 7.4 medium. The strength of the films increases after their treatment with CaCl2 at higher intervals forming an alginate network. The SA/LS blend (80/20) is subjected for sorption studies at variable pH 1.2 & 7.4, in order to test the suitability of the blends for controlled drug delivery. Further, experiments were conducted for de-crosslinking using 0.1M HCl. The solvent uptake for the blends decreased with increasing LS content in the blends. Blends were investigated by X-ray diffraction and Fourier Transform Infra-Red spectroscopy in order to study the crystallinity and molecular interactions. XRD confirms the reduction in cluster space in blends leading to lower uptake of solvent.
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spelling Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studiesSodium alginateblendsswellingbiomaterialswater soluble polymerscrosslinkingIn this article, Sodium alginate and Lignosulphonic acid blends were prepared in different weight ratios by solution casting method. Swelling experiments were conducted for Sodium alginate and its blends by adding calcium chloride for various intervals in a pH 7.4 medium. The strength of the films increases after their treatment with CaCl2 at higher intervals forming an alginate network. The SA/LS blend (80/20) is subjected for sorption studies at variable pH 1.2 & 7.4, in order to test the suitability of the blends for controlled drug delivery. Further, experiments were conducted for de-crosslinking using 0.1M HCl. The solvent uptake for the blends decreased with increasing LS content in the blends. Blends were investigated by X-ray diffraction and Fourier Transform Infra-Red spectroscopy in order to study the crystallinity and molecular interactions. XRD confirms the reduction in cluster space in blends leading to lower uptake of solvent.Associação Brasileira de Polímeros2013-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282013000100005Polímeros v.23 n.1 2013reponame:Polímeros (São Carlos. Online)instname:Associação Brasileira de Polímeros (ABPol)instacron:ABPO10.1590/S0104-14282013005000006info:eu-repo/semantics/openAccessReddy,S. GiridharPandit,Akanksha Saxenaeng2015-07-21T00:00:00Zoai:scielo:S0104-14282013000100005Revistahttp://www.scielo.br/pohttps://old.scielo.br/oai/scielo-oai.php||revista@abpol.org.br1678-51690104-1428opendoar:2015-07-21T00:00Polímeros (São Carlos. Online) - Associação Brasileira de Polímeros (ABPol)false
dc.title.none.fl_str_mv Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
title Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
spellingShingle Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
Reddy,S. Giridhar
Sodium alginate
blends
swelling
biomaterials
water soluble polymers
crosslinking
title_short Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
title_full Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
title_fullStr Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
title_full_unstemmed Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
title_sort Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
author Reddy,S. Giridhar
author_facet Reddy,S. Giridhar
Pandit,Akanksha Saxena
author_role author
author2 Pandit,Akanksha Saxena
author2_role author
dc.contributor.author.fl_str_mv Reddy,S. Giridhar
Pandit,Akanksha Saxena
dc.subject.por.fl_str_mv Sodium alginate
blends
swelling
biomaterials
water soluble polymers
crosslinking
topic Sodium alginate
blends
swelling
biomaterials
water soluble polymers
crosslinking
description In this article, Sodium alginate and Lignosulphonic acid blends were prepared in different weight ratios by solution casting method. Swelling experiments were conducted for Sodium alginate and its blends by adding calcium chloride for various intervals in a pH 7.4 medium. The strength of the films increases after their treatment with CaCl2 at higher intervals forming an alginate network. The SA/LS blend (80/20) is subjected for sorption studies at variable pH 1.2 & 7.4, in order to test the suitability of the blends for controlled drug delivery. Further, experiments were conducted for de-crosslinking using 0.1M HCl. The solvent uptake for the blends decreased with increasing LS content in the blends. Blends were investigated by X-ray diffraction and Fourier Transform Infra-Red spectroscopy in order to study the crystallinity and molecular interactions. XRD confirms the reduction in cluster space in blends leading to lower uptake of solvent.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282013000100005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282013000100005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0104-14282013005000006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Polímeros
publisher.none.fl_str_mv Associação Brasileira de Polímeros
dc.source.none.fl_str_mv Polímeros v.23 n.1 2013
reponame:Polímeros (São Carlos. Online)
instname:Associação Brasileira de Polímeros (ABPol)
instacron:ABPO
instname_str Associação Brasileira de Polímeros (ABPol)
instacron_str ABPO
institution ABPO
reponame_str Polímeros (São Carlos. Online)
collection Polímeros (São Carlos. Online)
repository.name.fl_str_mv Polímeros (São Carlos. Online) - Associação Brasileira de Polímeros (ABPol)
repository.mail.fl_str_mv ||revista@abpol.org.br
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