Management of weight loss in a patient with Prader-Willi syndrome with satietogenics: a case report
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | International Journal of Nutrology (Online) |
Texto Completo: | https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/288 |
Resumo: | Objective: To report the evolution and therapeutic approach in a patient with PraderWilli Syndrome (PWS) associated with literature data assessment with a focus on the pharmacological treatment of obesity in patients with this pathology, since there are currently not many studies that contribute or name a strategy with the use of satietogenics. Methods: The present study was elaborated according to the rules of CARE case report. Due to the cognitive impairment present in the syndrome, the patient’s mother was first contacted about the writing of this paper and was given consent through the signing of the Free and Informed Assent Term for this paper. The patient was treated at a hospital-adjacent Nutrology outpatient clinic in 2019. Case Description: YSP, 20 years old, diagnosed with PWS and Grade III obesity (initial BMI of 55.4kg/m², 140kg) attended the Nutrology outpatient clinic of Adriano Jorge Hospital Foundation – FHAJ in 2019 under referral from a third party, and his companion (relative) reporting hyperphagia and poor school performance, initially without a nutrition plan, during follow-up, nutritional guidance and multi-professional care have been initiated. Results: During the follow-up of the years 2019-2021, resulting from the SARS-CoV-2 pandemic in Brazil and the consequent confinement, the patient presented worsening anxiety and hyperphagia, evolving with increased binge eating and discontinuation of physical activities and diet adherence. During the follow-up in the same period, there were 03 returns denoting weight maintenance, later (2021) the use of on-label (Sibutramine), off-label (Fluoxetine), and Metformin medications were associated with the therapeutic regimen for obesity, due to evidence of insulin resistance. Final considerations: The patient evolved with progressive weight loss and better adherence to the food plan and physical activities. |
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International Journal of Nutrology (Online) |
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Management of weight loss in a patient with Prader-Willi syndrome with satietogenics: a case reportObjective: To report the evolution and therapeutic approach in a patient with PraderWilli Syndrome (PWS) associated with literature data assessment with a focus on the pharmacological treatment of obesity in patients with this pathology, since there are currently not many studies that contribute or name a strategy with the use of satietogenics. Methods: The present study was elaborated according to the rules of CARE case report. Due to the cognitive impairment present in the syndrome, the patient’s mother was first contacted about the writing of this paper and was given consent through the signing of the Free and Informed Assent Term for this paper. The patient was treated at a hospital-adjacent Nutrology outpatient clinic in 2019. Case Description: YSP, 20 years old, diagnosed with PWS and Grade III obesity (initial BMI of 55.4kg/m², 140kg) attended the Nutrology outpatient clinic of Adriano Jorge Hospital Foundation – FHAJ in 2019 under referral from a third party, and his companion (relative) reporting hyperphagia and poor school performance, initially without a nutrition plan, during follow-up, nutritional guidance and multi-professional care have been initiated. Results: During the follow-up of the years 2019-2021, resulting from the SARS-CoV-2 pandemic in Brazil and the consequent confinement, the patient presented worsening anxiety and hyperphagia, evolving with increased binge eating and discontinuation of physical activities and diet adherence. During the follow-up in the same period, there were 03 returns denoting weight maintenance, later (2021) the use of on-label (Sibutramine), off-label (Fluoxetine), and Metformin medications were associated with the therapeutic regimen for obesity, due to evidence of insulin resistance. Final considerations: The patient evolved with progressive weight loss and better adherence to the food plan and physical activities.MetaScience Press2023-05-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/28810.54448/ijn23214International Journal of Nutrology; Vol. 16 No. 2 (2023): International Journal of Nutrology (IJN) - March 20232595-28541984-301110.54448/ijn232reponame:International Journal of Nutrology (Online)instname:Associação Brasileira de Nutrologia (ABRAN)instacron:ABRANenghttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/288/276Copyright (c) 2023 José Marques Pina Neto, Larissa Erikarla Negreiros Madureira, Felipe Da Paixão Martinez Palhares, Rodrigo Fernandes Weyll Pimentel, Isolda Prado de Negreiros Nogueira Madurohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPina Neto, José MarquesMadureira, Larissa Erikarla NegreirosPalhares, Felipe Da Paixão MartinezPimentel, Rodrigo Fernandes WeyllMaduro, Isolda Prado de Negreiros Nogueira2023-05-04T20:51:56Zoai:ojs2.ijn.zotarellifilhoscientificworks.com:article/288Revistahttps://ijn.zotarellifilhoscientificworks.com/index.php/ijnONGhttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/oaiijn@zotarellifilhoscientificworks.com || editorchief@zotarellifilhoscientificworks.com10.544482595-28541984-3011opendoar:2023-05-04T20:51:56International Journal of Nutrology (Online) - Associação Brasileira de Nutrologia (ABRAN)false |
dc.title.none.fl_str_mv |
Management of weight loss in a patient with Prader-Willi syndrome with satietogenics: a case report |
title |
Management of weight loss in a patient with Prader-Willi syndrome with satietogenics: a case report |
spellingShingle |
Management of weight loss in a patient with Prader-Willi syndrome with satietogenics: a case report Pina Neto, José Marques |
title_short |
Management of weight loss in a patient with Prader-Willi syndrome with satietogenics: a case report |
title_full |
Management of weight loss in a patient with Prader-Willi syndrome with satietogenics: a case report |
title_fullStr |
Management of weight loss in a patient with Prader-Willi syndrome with satietogenics: a case report |
title_full_unstemmed |
Management of weight loss in a patient with Prader-Willi syndrome with satietogenics: a case report |
title_sort |
Management of weight loss in a patient with Prader-Willi syndrome with satietogenics: a case report |
author |
Pina Neto, José Marques |
author_facet |
Pina Neto, José Marques Madureira, Larissa Erikarla Negreiros Palhares, Felipe Da Paixão Martinez Pimentel, Rodrigo Fernandes Weyll Maduro, Isolda Prado de Negreiros Nogueira |
author_role |
author |
author2 |
Madureira, Larissa Erikarla Negreiros Palhares, Felipe Da Paixão Martinez Pimentel, Rodrigo Fernandes Weyll Maduro, Isolda Prado de Negreiros Nogueira |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Pina Neto, José Marques Madureira, Larissa Erikarla Negreiros Palhares, Felipe Da Paixão Martinez Pimentel, Rodrigo Fernandes Weyll Maduro, Isolda Prado de Negreiros Nogueira |
description |
Objective: To report the evolution and therapeutic approach in a patient with PraderWilli Syndrome (PWS) associated with literature data assessment with a focus on the pharmacological treatment of obesity in patients with this pathology, since there are currently not many studies that contribute or name a strategy with the use of satietogenics. Methods: The present study was elaborated according to the rules of CARE case report. Due to the cognitive impairment present in the syndrome, the patient’s mother was first contacted about the writing of this paper and was given consent through the signing of the Free and Informed Assent Term for this paper. The patient was treated at a hospital-adjacent Nutrology outpatient clinic in 2019. Case Description: YSP, 20 years old, diagnosed with PWS and Grade III obesity (initial BMI of 55.4kg/m², 140kg) attended the Nutrology outpatient clinic of Adriano Jorge Hospital Foundation – FHAJ in 2019 under referral from a third party, and his companion (relative) reporting hyperphagia and poor school performance, initially without a nutrition plan, during follow-up, nutritional guidance and multi-professional care have been initiated. Results: During the follow-up of the years 2019-2021, resulting from the SARS-CoV-2 pandemic in Brazil and the consequent confinement, the patient presented worsening anxiety and hyperphagia, evolving with increased binge eating and discontinuation of physical activities and diet adherence. During the follow-up in the same period, there were 03 returns denoting weight maintenance, later (2021) the use of on-label (Sibutramine), off-label (Fluoxetine), and Metformin medications were associated with the therapeutic regimen for obesity, due to evidence of insulin resistance. Final considerations: The patient evolved with progressive weight loss and better adherence to the food plan and physical activities. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-05-04 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/288 10.54448/ijn23214 |
url |
https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/288 |
identifier_str_mv |
10.54448/ijn23214 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/288/276 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MetaScience Press |
publisher.none.fl_str_mv |
MetaScience Press |
dc.source.none.fl_str_mv |
International Journal of Nutrology; Vol. 16 No. 2 (2023): International Journal of Nutrology (IJN) - March 2023 2595-2854 1984-3011 10.54448/ijn232 reponame:International Journal of Nutrology (Online) instname:Associação Brasileira de Nutrologia (ABRAN) instacron:ABRAN |
instname_str |
Associação Brasileira de Nutrologia (ABRAN) |
instacron_str |
ABRAN |
institution |
ABRAN |
reponame_str |
International Journal of Nutrology (Online) |
collection |
International Journal of Nutrology (Online) |
repository.name.fl_str_mv |
International Journal of Nutrology (Online) - Associação Brasileira de Nutrologia (ABRAN) |
repository.mail.fl_str_mv |
ijn@zotarellifilhoscientificworks.com || editorchief@zotarellifilhoscientificworks.com |
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