Dysbiosis and obesity: implications of the gut microbiota
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | International Journal of Nutrology (Online) |
Texto Completo: | https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/8 |
Resumo: | Introduction: Obesity has been considered a public health crisis, contributing as a risk factor for several important chronic diseases and even death. Considering this fact, it is noteworthy that there is a fundamental relationship between the intestine and health, and this organ is considered by modern medicine as our second brain in the concept of intestinal permeability. Within the evaluation of the food process, effective nutritional absorption can be altered due to imbalances, such as malabsorption, drug-nutrient interaction, changes in mucosal permeability, and, consequently, an imbalance in the gut microbiota. Dysbiosis is characterized by these negative changes that occur in the intestine. In this sense, the present systematic review study sought to answer: What influences can the microbiota composition have on the metabolic syndrome and obesity process? Objective: To elucidate the relationship between the presence of intestinal dysbiosis in the pathogenesis of obesity. Methods: This is a bibliographic review work where the MEDLINE, PubMed, and SciELO databases were consulted using the following descriptors: Human gut microbiota, obesity, dysbiosis. Results and Conclusion: Based on the literature that supports this theme, it was possible to observe that in the obese population there is an increase in bacteria of the genus Firmicutes and a decrease in the genus Bacteriodetes, with the blocking of factors and proteins that regulate the homeostasis of the absorption of lipids and fatty acids being observed thus being able to alter the energy metabolism leading to a greater accumulation of adipose tissue. |
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Dysbiosis and obesity: implications of the gut microbiotaHuman gut microbiotaObesityDysbiosisBowel changesIntroduction: Obesity has been considered a public health crisis, contributing as a risk factor for several important chronic diseases and even death. Considering this fact, it is noteworthy that there is a fundamental relationship between the intestine and health, and this organ is considered by modern medicine as our second brain in the concept of intestinal permeability. Within the evaluation of the food process, effective nutritional absorption can be altered due to imbalances, such as malabsorption, drug-nutrient interaction, changes in mucosal permeability, and, consequently, an imbalance in the gut microbiota. Dysbiosis is characterized by these negative changes that occur in the intestine. In this sense, the present systematic review study sought to answer: What influences can the microbiota composition have on the metabolic syndrome and obesity process? Objective: To elucidate the relationship between the presence of intestinal dysbiosis in the pathogenesis of obesity. Methods: This is a bibliographic review work where the MEDLINE, PubMed, and SciELO databases were consulted using the following descriptors: Human gut microbiota, obesity, dysbiosis. Results and Conclusion: Based on the literature that supports this theme, it was possible to observe that in the obese population there is an increase in bacteria of the genus Firmicutes and a decrease in the genus Bacteriodetes, with the blocking of factors and proteins that regulate the homeostasis of the absorption of lipids and fatty acids being observed thus being able to alter the energy metabolism leading to a greater accumulation of adipose tissue.MetaScience Press2021-11-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Articleapplication/pdfhttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/810.54448/ijn2135International Journal of Nutrology; Vol. 14 No. 3 (2021): International Journal of Nutrology (IJN)2595-28541984-301110.54448/ijn213reponame:International Journal of Nutrology (Online)instname:Associação Brasileira de Nutrologia (ABRAN)instacron:ABRANenghttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/8/5Copyright (c) 2021 International Journal of Nutrologyinfo:eu-repo/semantics/openAccessPinto, Alexandre CarliCavalcante, Danilo Everton CunhaAraújo, Etianne AndradeCabral, Francione MoreiraSantos, Jhonatas MotaCosta, Kaline Viana2021-11-05T01:18:56Zoai:ojs2.ijn.zotarellifilhoscientificworks.com:article/8Revistahttps://ijn.zotarellifilhoscientificworks.com/index.php/ijnONGhttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/oaiijn@zotarellifilhoscientificworks.com || editorchief@zotarellifilhoscientificworks.com10.544482595-28541984-3011opendoar:2021-11-05T01:18:56International Journal of Nutrology (Online) - Associação Brasileira de Nutrologia (ABRAN)false |
dc.title.none.fl_str_mv |
Dysbiosis and obesity: implications of the gut microbiota |
title |
Dysbiosis and obesity: implications of the gut microbiota |
spellingShingle |
Dysbiosis and obesity: implications of the gut microbiota Pinto, Alexandre Carli Human gut microbiota Obesity Dysbiosis Bowel changes |
title_short |
Dysbiosis and obesity: implications of the gut microbiota |
title_full |
Dysbiosis and obesity: implications of the gut microbiota |
title_fullStr |
Dysbiosis and obesity: implications of the gut microbiota |
title_full_unstemmed |
Dysbiosis and obesity: implications of the gut microbiota |
title_sort |
Dysbiosis and obesity: implications of the gut microbiota |
author |
Pinto, Alexandre Carli |
author_facet |
Pinto, Alexandre Carli Cavalcante, Danilo Everton Cunha Araújo, Etianne Andrade Cabral, Francione Moreira Santos, Jhonatas Mota Costa, Kaline Viana |
author_role |
author |
author2 |
Cavalcante, Danilo Everton Cunha Araújo, Etianne Andrade Cabral, Francione Moreira Santos, Jhonatas Mota Costa, Kaline Viana |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Pinto, Alexandre Carli Cavalcante, Danilo Everton Cunha Araújo, Etianne Andrade Cabral, Francione Moreira Santos, Jhonatas Mota Costa, Kaline Viana |
dc.subject.por.fl_str_mv |
Human gut microbiota Obesity Dysbiosis Bowel changes |
topic |
Human gut microbiota Obesity Dysbiosis Bowel changes |
description |
Introduction: Obesity has been considered a public health crisis, contributing as a risk factor for several important chronic diseases and even death. Considering this fact, it is noteworthy that there is a fundamental relationship between the intestine and health, and this organ is considered by modern medicine as our second brain in the concept of intestinal permeability. Within the evaluation of the food process, effective nutritional absorption can be altered due to imbalances, such as malabsorption, drug-nutrient interaction, changes in mucosal permeability, and, consequently, an imbalance in the gut microbiota. Dysbiosis is characterized by these negative changes that occur in the intestine. In this sense, the present systematic review study sought to answer: What influences can the microbiota composition have on the metabolic syndrome and obesity process? Objective: To elucidate the relationship between the presence of intestinal dysbiosis in the pathogenesis of obesity. Methods: This is a bibliographic review work where the MEDLINE, PubMed, and SciELO databases were consulted using the following descriptors: Human gut microbiota, obesity, dysbiosis. Results and Conclusion: Based on the literature that supports this theme, it was possible to observe that in the obese population there is an increase in bacteria of the genus Firmicutes and a decrease in the genus Bacteriodetes, with the blocking of factors and proteins that regulate the homeostasis of the absorption of lipids and fatty acids being observed thus being able to alter the energy metabolism leading to a greater accumulation of adipose tissue. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-11-05 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/8 10.54448/ijn2135 |
url |
https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/8 |
identifier_str_mv |
10.54448/ijn2135 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/8/5 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2021 International Journal of Nutrology info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2021 International Journal of Nutrology |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MetaScience Press |
publisher.none.fl_str_mv |
MetaScience Press |
dc.source.none.fl_str_mv |
International Journal of Nutrology; Vol. 14 No. 3 (2021): International Journal of Nutrology (IJN) 2595-2854 1984-3011 10.54448/ijn213 reponame:International Journal of Nutrology (Online) instname:Associação Brasileira de Nutrologia (ABRAN) instacron:ABRAN |
instname_str |
Associação Brasileira de Nutrologia (ABRAN) |
instacron_str |
ABRAN |
institution |
ABRAN |
reponame_str |
International Journal of Nutrology (Online) |
collection |
International Journal of Nutrology (Online) |
repository.name.fl_str_mv |
International Journal of Nutrology (Online) - Associação Brasileira de Nutrologia (ABRAN) |
repository.mail.fl_str_mv |
ijn@zotarellifilhoscientificworks.com || editorchief@zotarellifilhoscientificworks.com |
_version_ |
1792204587171577856 |