A systematic review and meta-analysis of interventions used to reduce exposure to house dust and their effect on the development and severity of asthma
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Ciência & Saúde Coletiva (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232008000600026 |
Resumo: | We assessed whether any household dust reduction intervention has the effect of increasing or decreasing the development or severity of atopic disease. Electronic searches on household intervention and atopic disease were conducted in 2007 in EMBASE, MEDLINE, and the Cochrane Central Register of Controlled Trials. We included randomized controlled trials comparing asthma outcomes in a household intervention group with either placebo intervention or no intervention. Meta-analyses on the prevention studies found that the interventions made no difference to the onset of wheeze but made a significant reduction in physician-diagnosed asthma. Meta-analysis of lung function outcomes indicated no improvement due to the interventions but found a reduction in symptom days. Qualitatively, health care was used less in those receiving interventions. However, in one study that compared intervention, placebo, and control arms, the reduction in heath care use was similar in the placebo and intervention arms. This review suggests that there is not sufficient evidence to suggest implementing hygiene measures in an attempt to improve outcomes in existing atopic disease, but interventions from birth in those at high risk of atopy are useful in preventing diagnosed asthma but not parental-reported wheeze. |
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A systematic review and meta-analysis of interventions used to reduce exposure to house dust and their effect on the development and severity of asthmaAsthmaAtopyMeta-analysisRandomized Control TrialSystematic reviewWe assessed whether any household dust reduction intervention has the effect of increasing or decreasing the development or severity of atopic disease. Electronic searches on household intervention and atopic disease were conducted in 2007 in EMBASE, MEDLINE, and the Cochrane Central Register of Controlled Trials. We included randomized controlled trials comparing asthma outcomes in a household intervention group with either placebo intervention or no intervention. Meta-analyses on the prevention studies found that the interventions made no difference to the onset of wheeze but made a significant reduction in physician-diagnosed asthma. Meta-analysis of lung function outcomes indicated no improvement due to the interventions but found a reduction in symptom days. Qualitatively, health care was used less in those receiving interventions. However, in one study that compared intervention, placebo, and control arms, the reduction in heath care use was similar in the placebo and intervention arms. This review suggests that there is not sufficient evidence to suggest implementing hygiene measures in an attempt to improve outcomes in existing atopic disease, but interventions from birth in those at high risk of atopy are useful in preventing diagnosed asthma but not parental-reported wheeze.ABRASCO - Associação Brasileira de Saúde Coletiva2008-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232008000600026Ciência & Saúde Coletiva v.13 n.6 2008reponame:Ciência & Saúde Coletiva (Online)instname:Associação Brasileira de Saúde Coletiva (ABRASCO)instacron:ABRASCO10.1590/S1413-81232008000600026info:eu-repo/semantics/openAccessMacdonald,ClareSternberg,AnnaHunter,Pauleng2008-09-30T00:00:00Zoai:scielo:S1413-81232008000600026Revistahttp://www.cienciaesaudecoletiva.com.brhttps://old.scielo.br/oai/scielo-oai.php||cienciasaudecoletiva@fiocruz.br1678-45611413-8123opendoar:2008-09-30T00:00Ciência & Saúde Coletiva (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO)false |
dc.title.none.fl_str_mv |
A systematic review and meta-analysis of interventions used to reduce exposure to house dust and their effect on the development and severity of asthma |
title |
A systematic review and meta-analysis of interventions used to reduce exposure to house dust and their effect on the development and severity of asthma |
spellingShingle |
A systematic review and meta-analysis of interventions used to reduce exposure to house dust and their effect on the development and severity of asthma Macdonald,Clare Asthma Atopy Meta-analysis Randomized Control Trial Systematic review |
title_short |
A systematic review and meta-analysis of interventions used to reduce exposure to house dust and their effect on the development and severity of asthma |
title_full |
A systematic review and meta-analysis of interventions used to reduce exposure to house dust and their effect on the development and severity of asthma |
title_fullStr |
A systematic review and meta-analysis of interventions used to reduce exposure to house dust and their effect on the development and severity of asthma |
title_full_unstemmed |
A systematic review and meta-analysis of interventions used to reduce exposure to house dust and their effect on the development and severity of asthma |
title_sort |
A systematic review and meta-analysis of interventions used to reduce exposure to house dust and their effect on the development and severity of asthma |
author |
Macdonald,Clare |
author_facet |
Macdonald,Clare Sternberg,Anna Hunter,Paul |
author_role |
author |
author2 |
Sternberg,Anna Hunter,Paul |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Macdonald,Clare Sternberg,Anna Hunter,Paul |
dc.subject.por.fl_str_mv |
Asthma Atopy Meta-analysis Randomized Control Trial Systematic review |
topic |
Asthma Atopy Meta-analysis Randomized Control Trial Systematic review |
description |
We assessed whether any household dust reduction intervention has the effect of increasing or decreasing the development or severity of atopic disease. Electronic searches on household intervention and atopic disease were conducted in 2007 in EMBASE, MEDLINE, and the Cochrane Central Register of Controlled Trials. We included randomized controlled trials comparing asthma outcomes in a household intervention group with either placebo intervention or no intervention. Meta-analyses on the prevention studies found that the interventions made no difference to the onset of wheeze but made a significant reduction in physician-diagnosed asthma. Meta-analysis of lung function outcomes indicated no improvement due to the interventions but found a reduction in symptom days. Qualitatively, health care was used less in those receiving interventions. However, in one study that compared intervention, placebo, and control arms, the reduction in heath care use was similar in the placebo and intervention arms. This review suggests that there is not sufficient evidence to suggest implementing hygiene measures in an attempt to improve outcomes in existing atopic disease, but interventions from birth in those at high risk of atopy are useful in preventing diagnosed asthma but not parental-reported wheeze. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232008000600026 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232008000600026 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1413-81232008000600026 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
ABRASCO - Associação Brasileira de Saúde Coletiva |
publisher.none.fl_str_mv |
ABRASCO - Associação Brasileira de Saúde Coletiva |
dc.source.none.fl_str_mv |
Ciência & Saúde Coletiva v.13 n.6 2008 reponame:Ciência & Saúde Coletiva (Online) instname:Associação Brasileira de Saúde Coletiva (ABRASCO) instacron:ABRASCO |
instname_str |
Associação Brasileira de Saúde Coletiva (ABRASCO) |
instacron_str |
ABRASCO |
institution |
ABRASCO |
reponame_str |
Ciência & Saúde Coletiva (Online) |
collection |
Ciência & Saúde Coletiva (Online) |
repository.name.fl_str_mv |
Ciência & Saúde Coletiva (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO) |
repository.mail.fl_str_mv |
||cienciasaudecoletiva@fiocruz.br |
_version_ |
1754213027207446528 |