Diagnosis and management of hypercalcemia associated with silicone-induced granuloma

Detalhes bibliográficos
Autor(a) principal: Hamadeh,Majdi
Data de Publicação: 2018
Outros Autores: Fares,Jawad
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Revista da Associação Médica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302018000700575
Resumo: SUMMARY Hypercalcemia associated with silicone-induced granuloma is a rare disease. Diagnosis can be tricky as it is established after ruling out other hypercalcemia-causing entities. In addition, management is customized depending on the patient's wishes and possible solutions. We present a male bodybuilder, in his thirties, with multiple silicone injections in his upper extremities, who developed hypercalcemia and urinary symptoms. Advanced laboratory tests ruled out various causes of hypercalcemia and CT imaging revealed nephrocalcinosis. A biopsy of the upper arm showed granulomatous tissue and inflammation. The patient necessitated two sessions of dialysis and corticosteroids were given to relieve symptoms and reverse laboratory abnormalities. Silicone-induced hypercalcemia should be on high alert because of the increasing trend of body contour enhancements with injections, implants and fillers. Treatment should be optimized depending on the patient's needs and condition.
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spelling Diagnosis and management of hypercalcemia associated with silicone-induced granulomaHypercalcemiaNephrocalcinosisDialysisGranulomaResistance trainingSilicones/adverse effectsInjections, intradermal/adverse effectsSUMMARY Hypercalcemia associated with silicone-induced granuloma is a rare disease. Diagnosis can be tricky as it is established after ruling out other hypercalcemia-causing entities. In addition, management is customized depending on the patient's wishes and possible solutions. We present a male bodybuilder, in his thirties, with multiple silicone injections in his upper extremities, who developed hypercalcemia and urinary symptoms. Advanced laboratory tests ruled out various causes of hypercalcemia and CT imaging revealed nephrocalcinosis. A biopsy of the upper arm showed granulomatous tissue and inflammation. The patient necessitated two sessions of dialysis and corticosteroids were given to relieve symptoms and reverse laboratory abnormalities. Silicone-induced hypercalcemia should be on high alert because of the increasing trend of body contour enhancements with injections, implants and fillers. Treatment should be optimized depending on the patient's needs and condition.Associação Médica Brasileira2018-07-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302018000700575Revista da Associação Médica Brasileira v.64 n.7 2018reponame:Revista da Associação Médica Brasileira (Online)instname:Associação Médica Brasileira (AMB)instacron:AMB10.1590/1806-9282.64.07.575info:eu-repo/semantics/openAccessHamadeh,MajdiFares,Jawadeng2018-10-10T00:00:00Zoai:scielo:S0104-42302018000700575Revistahttps://ramb.amb.org.br/ultimas-edicoes/#https://old.scielo.br/oai/scielo-oai.php||ramb@amb.org.br1806-92820104-4230opendoar:2018-10-10T00:00Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)false
dc.title.none.fl_str_mv Diagnosis and management of hypercalcemia associated with silicone-induced granuloma
title Diagnosis and management of hypercalcemia associated with silicone-induced granuloma
spellingShingle Diagnosis and management of hypercalcemia associated with silicone-induced granuloma
Hamadeh,Majdi
Hypercalcemia
Nephrocalcinosis
Dialysis
Granuloma
Resistance training
Silicones/adverse effects
Injections, intradermal/adverse effects
title_short Diagnosis and management of hypercalcemia associated with silicone-induced granuloma
title_full Diagnosis and management of hypercalcemia associated with silicone-induced granuloma
title_fullStr Diagnosis and management of hypercalcemia associated with silicone-induced granuloma
title_full_unstemmed Diagnosis and management of hypercalcemia associated with silicone-induced granuloma
title_sort Diagnosis and management of hypercalcemia associated with silicone-induced granuloma
author Hamadeh,Majdi
author_facet Hamadeh,Majdi
Fares,Jawad
author_role author
author2 Fares,Jawad
author2_role author
dc.contributor.author.fl_str_mv Hamadeh,Majdi
Fares,Jawad
dc.subject.por.fl_str_mv Hypercalcemia
Nephrocalcinosis
Dialysis
Granuloma
Resistance training
Silicones/adverse effects
Injections, intradermal/adverse effects
topic Hypercalcemia
Nephrocalcinosis
Dialysis
Granuloma
Resistance training
Silicones/adverse effects
Injections, intradermal/adverse effects
description SUMMARY Hypercalcemia associated with silicone-induced granuloma is a rare disease. Diagnosis can be tricky as it is established after ruling out other hypercalcemia-causing entities. In addition, management is customized depending on the patient's wishes and possible solutions. We present a male bodybuilder, in his thirties, with multiple silicone injections in his upper extremities, who developed hypercalcemia and urinary symptoms. Advanced laboratory tests ruled out various causes of hypercalcemia and CT imaging revealed nephrocalcinosis. A biopsy of the upper arm showed granulomatous tissue and inflammation. The patient necessitated two sessions of dialysis and corticosteroids were given to relieve symptoms and reverse laboratory abnormalities. Silicone-induced hypercalcemia should be on high alert because of the increasing trend of body contour enhancements with injections, implants and fillers. Treatment should be optimized depending on the patient's needs and condition.
publishDate 2018
dc.date.none.fl_str_mv 2018-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302018000700575
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302018000700575
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1806-9282.64.07.575
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Médica Brasileira
publisher.none.fl_str_mv Associação Médica Brasileira
dc.source.none.fl_str_mv Revista da Associação Médica Brasileira v.64 n.7 2018
reponame:Revista da Associação Médica Brasileira (Online)
instname:Associação Médica Brasileira (AMB)
instacron:AMB
instname_str Associação Médica Brasileira (AMB)
instacron_str AMB
institution AMB
reponame_str Revista da Associação Médica Brasileira (Online)
collection Revista da Associação Médica Brasileira (Online)
repository.name.fl_str_mv Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)
repository.mail.fl_str_mv ||ramb@amb.org.br
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