Diagnosis and management of hypercalcemia associated with silicone-induced granuloma
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Revista da Associação Médica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302018000700575 |
Resumo: | SUMMARY Hypercalcemia associated with silicone-induced granuloma is a rare disease. Diagnosis can be tricky as it is established after ruling out other hypercalcemia-causing entities. In addition, management is customized depending on the patient's wishes and possible solutions. We present a male bodybuilder, in his thirties, with multiple silicone injections in his upper extremities, who developed hypercalcemia and urinary symptoms. Advanced laboratory tests ruled out various causes of hypercalcemia and CT imaging revealed nephrocalcinosis. A biopsy of the upper arm showed granulomatous tissue and inflammation. The patient necessitated two sessions of dialysis and corticosteroids were given to relieve symptoms and reverse laboratory abnormalities. Silicone-induced hypercalcemia should be on high alert because of the increasing trend of body contour enhancements with injections, implants and fillers. Treatment should be optimized depending on the patient's needs and condition. |
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Diagnosis and management of hypercalcemia associated with silicone-induced granulomaHypercalcemiaNephrocalcinosisDialysisGranulomaResistance trainingSilicones/adverse effectsInjections, intradermal/adverse effectsSUMMARY Hypercalcemia associated with silicone-induced granuloma is a rare disease. Diagnosis can be tricky as it is established after ruling out other hypercalcemia-causing entities. In addition, management is customized depending on the patient's wishes and possible solutions. We present a male bodybuilder, in his thirties, with multiple silicone injections in his upper extremities, who developed hypercalcemia and urinary symptoms. Advanced laboratory tests ruled out various causes of hypercalcemia and CT imaging revealed nephrocalcinosis. A biopsy of the upper arm showed granulomatous tissue and inflammation. The patient necessitated two sessions of dialysis and corticosteroids were given to relieve symptoms and reverse laboratory abnormalities. Silicone-induced hypercalcemia should be on high alert because of the increasing trend of body contour enhancements with injections, implants and fillers. Treatment should be optimized depending on the patient's needs and condition.Associação Médica Brasileira2018-07-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302018000700575Revista da Associação Médica Brasileira v.64 n.7 2018reponame:Revista da Associação Médica Brasileira (Online)instname:Associação Médica Brasileira (AMB)instacron:AMB10.1590/1806-9282.64.07.575info:eu-repo/semantics/openAccessHamadeh,MajdiFares,Jawadeng2018-10-10T00:00:00Zoai:scielo:S0104-42302018000700575Revistahttps://ramb.amb.org.br/ultimas-edicoes/#https://old.scielo.br/oai/scielo-oai.php||ramb@amb.org.br1806-92820104-4230opendoar:2018-10-10T00:00Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)false |
dc.title.none.fl_str_mv |
Diagnosis and management of hypercalcemia associated with silicone-induced granuloma |
title |
Diagnosis and management of hypercalcemia associated with silicone-induced granuloma |
spellingShingle |
Diagnosis and management of hypercalcemia associated with silicone-induced granuloma Hamadeh,Majdi Hypercalcemia Nephrocalcinosis Dialysis Granuloma Resistance training Silicones/adverse effects Injections, intradermal/adverse effects |
title_short |
Diagnosis and management of hypercalcemia associated with silicone-induced granuloma |
title_full |
Diagnosis and management of hypercalcemia associated with silicone-induced granuloma |
title_fullStr |
Diagnosis and management of hypercalcemia associated with silicone-induced granuloma |
title_full_unstemmed |
Diagnosis and management of hypercalcemia associated with silicone-induced granuloma |
title_sort |
Diagnosis and management of hypercalcemia associated with silicone-induced granuloma |
author |
Hamadeh,Majdi |
author_facet |
Hamadeh,Majdi Fares,Jawad |
author_role |
author |
author2 |
Fares,Jawad |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Hamadeh,Majdi Fares,Jawad |
dc.subject.por.fl_str_mv |
Hypercalcemia Nephrocalcinosis Dialysis Granuloma Resistance training Silicones/adverse effects Injections, intradermal/adverse effects |
topic |
Hypercalcemia Nephrocalcinosis Dialysis Granuloma Resistance training Silicones/adverse effects Injections, intradermal/adverse effects |
description |
SUMMARY Hypercalcemia associated with silicone-induced granuloma is a rare disease. Diagnosis can be tricky as it is established after ruling out other hypercalcemia-causing entities. In addition, management is customized depending on the patient's wishes and possible solutions. We present a male bodybuilder, in his thirties, with multiple silicone injections in his upper extremities, who developed hypercalcemia and urinary symptoms. Advanced laboratory tests ruled out various causes of hypercalcemia and CT imaging revealed nephrocalcinosis. A biopsy of the upper arm showed granulomatous tissue and inflammation. The patient necessitated two sessions of dialysis and corticosteroids were given to relieve symptoms and reverse laboratory abnormalities. Silicone-induced hypercalcemia should be on high alert because of the increasing trend of body contour enhancements with injections, implants and fillers. Treatment should be optimized depending on the patient's needs and condition. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302018000700575 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302018000700575 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1806-9282.64.07.575 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Médica Brasileira |
publisher.none.fl_str_mv |
Associação Médica Brasileira |
dc.source.none.fl_str_mv |
Revista da Associação Médica Brasileira v.64 n.7 2018 reponame:Revista da Associação Médica Brasileira (Online) instname:Associação Médica Brasileira (AMB) instacron:AMB |
instname_str |
Associação Médica Brasileira (AMB) |
instacron_str |
AMB |
institution |
AMB |
reponame_str |
Revista da Associação Médica Brasileira (Online) |
collection |
Revista da Associação Médica Brasileira (Online) |
repository.name.fl_str_mv |
Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB) |
repository.mail.fl_str_mv |
||ramb@amb.org.br |
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1754212833415921664 |