Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia

Detalhes bibliográficos
Autor(a) principal: Figueiredo,Maria Stella
Data de Publicação: 2004
Outros Autores: Vicari,Perla, Kimura,Eliza Yuriko Sugano, Antunes,Sandra Vallin, Yamamoto,Mihoko
Tipo de documento: Artigo
Idioma: eng
Título da fonte: São Paulo medical journal (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802004000600009
Resumo: CONTEXT: The prognosis of severe aplastic anemia has improved since the introduction of bone marrow transplantation and treatment with antithymocyte globulin. In contrast to the success of these protocols, studies with long term follow-up have shown the occurrence of clonal diseases such as paroxysmal nocturnal hemoglobinuria, myelodysplastic syndrome and acute leukemia in aplastic anemia. CASE REPORT: We report the first case of a Brazilian patient with aplastic anemia who developed myelodysplastic syndrome and acute myeloid leukemia showing acquired hemoglobin H and increased fetal hemoglobin.
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spelling Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemiaHemoglobin HDiseaseAplastic anemiaMyeloid leukemiaMyelodysplastic syndromesCONTEXT: The prognosis of severe aplastic anemia has improved since the introduction of bone marrow transplantation and treatment with antithymocyte globulin. In contrast to the success of these protocols, studies with long term follow-up have shown the occurrence of clonal diseases such as paroxysmal nocturnal hemoglobinuria, myelodysplastic syndrome and acute leukemia in aplastic anemia. CASE REPORT: We report the first case of a Brazilian patient with aplastic anemia who developed myelodysplastic syndrome and acute myeloid leukemia showing acquired hemoglobin H and increased fetal hemoglobin.Associação Paulista de Medicina - APM2004-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802004000600009Sao Paulo Medical Journal v.122 n.6 2004reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31802004000600009info:eu-repo/semantics/openAccessFigueiredo,Maria StellaVicari,PerlaKimura,Eliza Yuriko SuganoAntunes,Sandra VallinYamamoto,Mihokoeng2005-02-02T00:00:00Zoai:scielo:S1516-31802004000600009Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2005-02-02T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia
title Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia
spellingShingle Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia
Figueiredo,Maria Stella
Hemoglobin H
Disease
Aplastic anemia
Myeloid leukemia
Myelodysplastic syndromes
title_short Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia
title_full Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia
title_fullStr Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia
title_full_unstemmed Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia
title_sort Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia
author Figueiredo,Maria Stella
author_facet Figueiredo,Maria Stella
Vicari,Perla
Kimura,Eliza Yuriko Sugano
Antunes,Sandra Vallin
Yamamoto,Mihoko
author_role author
author2 Vicari,Perla
Kimura,Eliza Yuriko Sugano
Antunes,Sandra Vallin
Yamamoto,Mihoko
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Figueiredo,Maria Stella
Vicari,Perla
Kimura,Eliza Yuriko Sugano
Antunes,Sandra Vallin
Yamamoto,Mihoko
dc.subject.por.fl_str_mv Hemoglobin H
Disease
Aplastic anemia
Myeloid leukemia
Myelodysplastic syndromes
topic Hemoglobin H
Disease
Aplastic anemia
Myeloid leukemia
Myelodysplastic syndromes
description CONTEXT: The prognosis of severe aplastic anemia has improved since the introduction of bone marrow transplantation and treatment with antithymocyte globulin. In contrast to the success of these protocols, studies with long term follow-up have shown the occurrence of clonal diseases such as paroxysmal nocturnal hemoglobinuria, myelodysplastic syndrome and acute leukemia in aplastic anemia. CASE REPORT: We report the first case of a Brazilian patient with aplastic anemia who developed myelodysplastic syndrome and acute myeloid leukemia showing acquired hemoglobin H and increased fetal hemoglobin.
publishDate 2004
dc.date.none.fl_str_mv 2004-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802004000600009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802004000600009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-31802004000600009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv Sao Paulo Medical Journal v.122 n.6 2004
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
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