Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections

Detalhes bibliográficos
Autor(a) principal: Martínez-Espinosa, Flor Ernestina
Data de Publicação: 2004
Outros Autores: Ribeiro, Cláudio Tadeu Daniel, Alecrim, Wilson Duarte
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/37393
Resumo: Fundação de Medicina Tropical do Amazonas. Manaus, AM, Brasil / Centro Universitário Nilton Lins, Manaus, AM, Brasil.
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spelling Martínez-Espinosa, Flor ErnestinaRibeiro, Cláudio Tadeu DanielAlecrim, Wilson Duarte2019-11-26T15:30:45Z2019-11-26T15:30:45Z2004MARTINEZ-ESPINOZA, Flor Ernestina; RIBEIRO, Cláudio Tadeu Daniel; ALECRIM, Wilson Duarte. Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 99, n. 1, p. 19-21, Feb. 2004.0074-0206https://www.arca.fiocruz.br/handle/icict/3739310.1590/S0074-027620040001000031678-8060engFundação Oswaldo Cruz. Instituto Oswaldo CruzMaláriaGravidezPlasmodium falciparumPlasmodium vivaxAmazônia brasileiraAmérica do SulTransmissão instávelMalariaPregnancyPlasmodium falciparumPlasmodium vivaxInstable transmissionBrazilian AmazonSouth AmericaMalaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infectionsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação de Medicina Tropical do Amazonas. Manaus, AM, Brasil / Centro Universitário Nilton Lins, Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Centro Colaborador da WHO Para Pesquisa e Treinamento em Imunulogia de Doenças Parasitárias. Rio de Janeiro, RJ, Brasil. Rio de Janeiro, RJ, Brasil.Fundação de Medicina Tropical do Amazonas. Manaus, AM, Brasil / Centro Universitário Nilton Lins, Manaus, AM, Brasil.Malaria remains globally the most important parasitic disease of man. Data on its deleterious effects during pregnancy have been extensively documented in hyperendemic, holoendemic, and mesoendemic areas – from Africa and Asia – where Plasmodium falciparum is responsible for almost all infections. However, knowledge about malaria during pregnancy in areas where transmission is unstable and P. vivax is the most prevalent species, such as the Brazilian Amazon, is scarce. Here, we report a preliminary cross sectional descriptive study, carried out at the Fundação de Medicina Tropical do Amazonas, a reference centre for diagnosis and treatment of tropical diseases in the west-Amazon (Manaus, Brazil). A total of 1699 febrile childbearing age women had positive thick blood smears to Plasmodium species, between January and November 1997: 1401 (82.5%) were positive for P. vivax, 286 (16.8%) for P. falciparum and 12 (0.07%) carried mixed infections. From the malarious patients, 195 were pregnant. The ratio of P. falciparum to P. vivax infections in the group of non-pregnant infected women was 1:5.6 while it was 1:2.3 in that of pregnant infected ones. Similar rates or even proportionally more vivax infections during pregnancy were expected to occur, in function of the contraindication of primaquine with the resulting increased P. vivax relapse rates. Such an observation suggests that the mechanism of resistance/susceptibility to infection and/or malaria pathogenesis in pregnant women may differ according to Plasmodium species and that the extensively described increase in the frequencies of malaria infection during pregnancy may be specifically due to P. falciparum infection.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/37393/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALClaudioTDRibeiro_etal_IOC_2004.pdfClaudioTDRibeiro_etal_IOC_2004.pdfapplication/pdf54051https://www.arca.fiocruz.br/bitstream/icict/37393/2/ClaudioTDRibeiro_etal_IOC_2004.pdfc021d0ade1a9e7d42de0572d23f23411MD52TEXTClaudioTDRibeiro_etal_IOC_2004.pdf.txtClaudioTDRibeiro_etal_IOC_2004.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections
title Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections
spellingShingle Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections
Martínez-Espinosa, Flor Ernestina
Malária
Gravidez
Plasmodium falciparum
Plasmodium vivax
Amazônia brasileira
América do Sul
Transmissão instável
Malaria
Pregnancy
Plasmodium falciparum
Plasmodium vivax
Instable transmission
Brazilian Amazon
South America
title_short Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections
title_full Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections
title_fullStr Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections
title_full_unstemmed Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections
title_sort Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections
author Martínez-Espinosa, Flor Ernestina
author_facet Martínez-Espinosa, Flor Ernestina
Ribeiro, Cláudio Tadeu Daniel
Alecrim, Wilson Duarte
author_role author
author2 Ribeiro, Cláudio Tadeu Daniel
Alecrim, Wilson Duarte
author2_role author
author
dc.contributor.author.fl_str_mv Martínez-Espinosa, Flor Ernestina
Ribeiro, Cláudio Tadeu Daniel
Alecrim, Wilson Duarte
dc.subject.other.pt_BR.fl_str_mv Malária
Gravidez
Plasmodium falciparum
Plasmodium vivax
Amazônia brasileira
América do Sul
Transmissão instável
topic Malária
Gravidez
Plasmodium falciparum
Plasmodium vivax
Amazônia brasileira
América do Sul
Transmissão instável
Malaria
Pregnancy
Plasmodium falciparum
Plasmodium vivax
Instable transmission
Brazilian Amazon
South America
dc.subject.en.pt_BR.fl_str_mv Malaria
Pregnancy
Plasmodium falciparum
Plasmodium vivax
Instable transmission
Brazilian Amazon
South America
description Fundação de Medicina Tropical do Amazonas. Manaus, AM, Brasil / Centro Universitário Nilton Lins, Manaus, AM, Brasil.
publishDate 2004
dc.date.issued.fl_str_mv 2004
dc.date.accessioned.fl_str_mv 2019-11-26T15:30:45Z
dc.date.available.fl_str_mv 2019-11-26T15:30:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MARTINEZ-ESPINOZA, Flor Ernestina; RIBEIRO, Cláudio Tadeu Daniel; ALECRIM, Wilson Duarte. Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 99, n. 1, p. 19-21, Feb. 2004.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/37393
dc.identifier.issn.pt_BR.fl_str_mv 0074-0206
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02762004000100003
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv MARTINEZ-ESPINOZA, Flor Ernestina; RIBEIRO, Cláudio Tadeu Daniel; ALECRIM, Wilson Duarte. Malaria during Pregnancy in a Reference Centre from the Brazilian Amazon: Unexpected Increase in the Frequency of Plasmodium falciparum Infections. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 99, n. 1, p. 19-21, Feb. 2004.
0074-0206
10.1590/S0074-02762004000100003
1678-8060
url https://www.arca.fiocruz.br/handle/icict/37393
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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