Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/29051 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular Aplicada a Micobactérias. Rio de Janeiro, RJ. Brasil. |
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Fontes, Amanda Nogueira BrumSakamuri, Rama MurtyBaptista, Ida Maria Foschiani DiasUra, SomeiMoraes, Milton OzórioMartinez, Alejandra NóbregaSarno, Euzenir NunesBrennan, Patrick J.Vissa, Varalakshmi D.Suffys, Philip Noel2018-09-25T17:24:17Z2018-09-25T17:24:17Z2009FONTES, Amanda Nogueira Brum; et al. Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients. Lepr Rev., v 80, p.302–315, 2009.0305-7518https://www.arca.fiocruz.br/handle/icict/29051engBritish Leprosy Relief Assoc.Mycobacterium lepraeHanseníasediversidade genéticaPacientesMycobacterium lepraeLeprosygenetic diversitypatientsGenetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patientsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular Aplicada a Micobactérias. Rio de Janeiro, RJ. Brasil.Colorado State University. Department of Microbiology, Immunology and Pathology. Fort Collins, Colorado, USA.Instituto Lauro de Souza Lima, Bauru. SP, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.Colorado State University. Department of Microbiology, Immunology and Pathology. Fort Collins, Colorado, USA.Colorado State University. Department of Microbiology, Immunology and Pathology. Fort Collins, Colorado, USA.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular Aplicada a Micobactérias. Rio de Janeiro, RJ. Brasil.Introduction Leprosy is a chronic disease caused by infection with Mycobacterium leprae, an obligate intracellular parasite. A problem in studying the transmission of leprosy is the small amount of variation in bacterial genomic DNA. The discovery of variable number of tandem repeats (VNTRs) allowed the detection of strain variation in areas with a high prevalence of leprosy. Four genotypes of M. leprae based on three single-nucleotide polymorphism (SNPs) were also discovered to be useful for analysis of the global spread of leprosy.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/29051/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALamanda_fontes_etal_IOC_2009.pdfamanda_fontes_etal_IOC_2009.pdfapplication/pdf376703https://www.arca.fiocruz.br/bitstream/icict/29051/2/amanda_fontes_etal_IOC_2009.pdfec0c4b7b9b14df59fc4f776733a26280MD52TEXTamanda_fontes_etal_IOC_2009.pdf.txtamanda_fontes_etal_IOC_2009.pdf.txtExtracted texttext/plain32286https://www.arca.fiocruz.br/bitstream/icict/29051/3/amanda_fontes_etal_IOC_2009.pdf.txt3dcf6cee098db3dcaa98277d82dfad04MD53icict/290512018-09-26 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dc.title.pt_BR.fl_str_mv |
Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients |
title |
Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients |
spellingShingle |
Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients Fontes, Amanda Nogueira Brum Mycobacterium leprae Hanseníase diversidade genética Pacientes Mycobacterium leprae Leprosy genetic diversity patients |
title_short |
Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients |
title_full |
Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients |
title_fullStr |
Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients |
title_full_unstemmed |
Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients |
title_sort |
Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients |
author |
Fontes, Amanda Nogueira Brum |
author_facet |
Fontes, Amanda Nogueira Brum Sakamuri, Rama Murty Baptista, Ida Maria Foschiani Dias Ura, Somei Moraes, Milton Ozório Martinez, Alejandra Nóbrega Sarno, Euzenir Nunes Brennan, Patrick J. Vissa, Varalakshmi D. Suffys, Philip Noel |
author_role |
author |
author2 |
Sakamuri, Rama Murty Baptista, Ida Maria Foschiani Dias Ura, Somei Moraes, Milton Ozório Martinez, Alejandra Nóbrega Sarno, Euzenir Nunes Brennan, Patrick J. Vissa, Varalakshmi D. Suffys, Philip Noel |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Fontes, Amanda Nogueira Brum Sakamuri, Rama Murty Baptista, Ida Maria Foschiani Dias Ura, Somei Moraes, Milton Ozório Martinez, Alejandra Nóbrega Sarno, Euzenir Nunes Brennan, Patrick J. Vissa, Varalakshmi D. Suffys, Philip Noel |
dc.subject.other.pt_BR.fl_str_mv |
Mycobacterium leprae Hanseníase diversidade genética Pacientes |
topic |
Mycobacterium leprae Hanseníase diversidade genética Pacientes Mycobacterium leprae Leprosy genetic diversity patients |
dc.subject.en.pt_BR.fl_str_mv |
Mycobacterium leprae Leprosy genetic diversity patients |
description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular Aplicada a Micobactérias. Rio de Janeiro, RJ. Brasil. |
publishDate |
2009 |
dc.date.issued.fl_str_mv |
2009 |
dc.date.accessioned.fl_str_mv |
2018-09-25T17:24:17Z |
dc.date.available.fl_str_mv |
2018-09-25T17:24:17Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
FONTES, Amanda Nogueira Brum; et al. Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients. Lepr Rev., v 80, p.302–315, 2009. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/29051 |
dc.identifier.issn.pt_BR.fl_str_mv |
0305-7518 |
identifier_str_mv |
FONTES, Amanda Nogueira Brum; et al. Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients. Lepr Rev., v 80, p.302–315, 2009. 0305-7518 |
url |
https://www.arca.fiocruz.br/handle/icict/29051 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
British Leprosy Relief Assoc. |
publisher.none.fl_str_mv |
British Leprosy Relief Assoc. |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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