Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients

Detalhes bibliográficos
Autor(a) principal: Fontes, Amanda Nogueira Brum
Data de Publicação: 2009
Outros Autores: Sakamuri, Rama Murty, Baptista, Ida Maria Foschiani Dias, Ura, Somei, Moraes, Milton Ozório, Martinez, Alejandra Nóbrega, Sarno, Euzenir Nunes, Brennan, Patrick J., Vissa, Varalakshmi D., Suffys, Philip Noel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/29051
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular Aplicada a Micobactérias. Rio de Janeiro, RJ. Brasil.
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spelling Fontes, Amanda Nogueira BrumSakamuri, Rama MurtyBaptista, Ida Maria Foschiani DiasUra, SomeiMoraes, Milton OzórioMartinez, Alejandra NóbregaSarno, Euzenir NunesBrennan, Patrick J.Vissa, Varalakshmi D.Suffys, Philip Noel2018-09-25T17:24:17Z2018-09-25T17:24:17Z2009FONTES, Amanda Nogueira Brum; et al. Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients. Lepr Rev., v 80, p.302–315, 2009.0305-7518https://www.arca.fiocruz.br/handle/icict/29051engBritish Leprosy Relief Assoc.Mycobacterium lepraeHanseníasediversidade genéticaPacientesMycobacterium lepraeLeprosygenetic diversitypatientsGenetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patientsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular Aplicada a Micobactérias. Rio de Janeiro, RJ. Brasil.Colorado State University. Department of Microbiology, Immunology and Pathology. Fort Collins, Colorado, USA.Instituto Lauro de Souza Lima, Bauru. SP, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.Colorado State University. Department of Microbiology, Immunology and Pathology. Fort Collins, Colorado, USA.Colorado State University. Department of Microbiology, Immunology and Pathology. Fort Collins, Colorado, USA.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular Aplicada a Micobactérias. Rio de Janeiro, RJ. Brasil.Introduction Leprosy is a chronic disease caused by infection with Mycobacterium leprae, an obligate intracellular parasite. A problem in studying the transmission of leprosy is the small amount of variation in bacterial genomic DNA. The discovery of variable number of tandem repeats (VNTRs) allowed the detection of strain variation in areas with a high prevalence of leprosy. Four genotypes of M. leprae based on three single-nucleotide polymorphism (SNPs) were also discovered to be useful for analysis of the global spread of leprosy.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/29051/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALamanda_fontes_etal_IOC_2009.pdfamanda_fontes_etal_IOC_2009.pdfapplication/pdf376703https://www.arca.fiocruz.br/bitstream/icict/29051/2/amanda_fontes_etal_IOC_2009.pdfec0c4b7b9b14df59fc4f776733a26280MD52TEXTamanda_fontes_etal_IOC_2009.pdf.txtamanda_fontes_etal_IOC_2009.pdf.txtExtracted texttext/plain32286https://www.arca.fiocruz.br/bitstream/icict/29051/3/amanda_fontes_etal_IOC_2009.pdf.txt3dcf6cee098db3dcaa98277d82dfad04MD53icict/290512018-09-26 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dc.title.pt_BR.fl_str_mv Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients
title Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients
spellingShingle Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients
Fontes, Amanda Nogueira Brum
Mycobacterium leprae
Hanseníase
diversidade genética
Pacientes
Mycobacterium leprae
Leprosy
genetic diversity
patients
title_short Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients
title_full Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients
title_fullStr Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients
title_full_unstemmed Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients
title_sort Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients
author Fontes, Amanda Nogueira Brum
author_facet Fontes, Amanda Nogueira Brum
Sakamuri, Rama Murty
Baptista, Ida Maria Foschiani Dias
Ura, Somei
Moraes, Milton Ozório
Martinez, Alejandra Nóbrega
Sarno, Euzenir Nunes
Brennan, Patrick J.
Vissa, Varalakshmi D.
Suffys, Philip Noel
author_role author
author2 Sakamuri, Rama Murty
Baptista, Ida Maria Foschiani Dias
Ura, Somei
Moraes, Milton Ozório
Martinez, Alejandra Nóbrega
Sarno, Euzenir Nunes
Brennan, Patrick J.
Vissa, Varalakshmi D.
Suffys, Philip Noel
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Fontes, Amanda Nogueira Brum
Sakamuri, Rama Murty
Baptista, Ida Maria Foschiani Dias
Ura, Somei
Moraes, Milton Ozório
Martinez, Alejandra Nóbrega
Sarno, Euzenir Nunes
Brennan, Patrick J.
Vissa, Varalakshmi D.
Suffys, Philip Noel
dc.subject.other.pt_BR.fl_str_mv Mycobacterium leprae
Hanseníase
diversidade genética
Pacientes
topic Mycobacterium leprae
Hanseníase
diversidade genética
Pacientes
Mycobacterium leprae
Leprosy
genetic diversity
patients
dc.subject.en.pt_BR.fl_str_mv Mycobacterium leprae
Leprosy
genetic diversity
patients
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular Aplicada a Micobactérias. Rio de Janeiro, RJ. Brasil.
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2018-09-25T17:24:17Z
dc.date.available.fl_str_mv 2018-09-25T17:24:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv FONTES, Amanda Nogueira Brum; et al. Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients. Lepr Rev., v 80, p.302–315, 2009.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/29051
dc.identifier.issn.pt_BR.fl_str_mv 0305-7518
identifier_str_mv FONTES, Amanda Nogueira Brum; et al. Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients. Lepr Rev., v 80, p.302–315, 2009.
0305-7518
url https://www.arca.fiocruz.br/handle/icict/29051
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv British Leprosy Relief Assoc.
publisher.none.fl_str_mv British Leprosy Relief Assoc.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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collection Repositório Institucional da FIOCRUZ (ARCA)
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