Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes

Monteiro, Wuelton Marcelo; Sousa, Jose Diego Brito; Silva, Djane Baía da; Melo, Gisely Cardoso de; Siqueira, André Machado; Val, Fernando; Daniel-Ribeiro, Cláudio Tadeu; Lacerda, Marcus Vinicius Guimarães

Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes

Detalhes bibliográficos
Autor(a) principal:	Monteiro, Wuelton Marcelo
Data de Publicação:	2020
Outros Autores:	Sousa, Jose Diego Brito, Silva, Djane Baía da, Melo, Gisely Cardoso de, Siqueira, André Machado, Val, Fernando, Daniel-Ribeiro, Cláudio Tadeu, Lacerda, Marcus Vinicius Guimarães
Tipo de documento:	Artigo
Idioma:	eng
Título da fonte:	Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo:	https://www.arca.fiocruz.br/handle/icict/40754
Resumo:	Devido a pandemia mundial do COVID-19, o artigo da revista foi liberado em acesso aberto durante o ano de 2020, visando divulgação e disseminação.

Metadados do item

id	CRUZ_087117fac575fbed84cc58f738fa9be6
oai_identifier_str	oai:www.arca.fiocruz.br:icict/40754
network_acronym_str	CRUZ
network_name_str	Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str	2135
spelling	Monteiro, Wuelton MarceloSousa, Jose Diego BritoSilva, Djane Baía daMelo, Gisely Cardoso deSiqueira, André MachadoVal, FernandoDaniel-Ribeiro, Cláudio TadeuLacerda, Marcus Vinicius Guimarães2020-04-14T18:55:35Z2020-04-14T18:55:35Z2020MONTEIRO, Wuelton Marcelo et al. Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes. Revista da Sociedade Brasileria de Medicina Tropical, Uberaba, v. 53, p. 1-3, 2020.0037-8682https://www.arca.fiocruz.br/handle/icict/4075410.1590/0037-8682-0155-20201678-9849Devido a pandemia mundial do COVID-19, o artigo da revista foi liberado em acesso aberto durante o ano de 2020, visando divulgação e disseminação.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Departamento de Ensino e Pesquisa. Manaus, AM, Brasil. / Universidade do Estado do Amazonas. Programa de Pós-Graduação em Medicina Tropical. Manaus, AM, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Departamento de Ensino e Pesquisa. Manaus, AM, Brasil. / Universidade do Estado do Amazonas. Programa de Pós-Graduação em Medicina Tropical. Manaus, AM, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Departamento de Ensino e Pesquisa. Manaus, AM, Brasil. / Universidade do Estado do Amazonas. Programa de Pós-Graduação em Medicina Tropical. Manaus, AM, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Departamento de Ensino e Pesquisa. Manaus, AM, Brasil. / Universidade do Estado do Amazonas. Programa de Pós-Graduação em Medicina Tropical. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Carlos Chagas. Rio de Janeiro, RJ, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Departamento de Ensino e Pesquisa. Manaus, AM, Brasil. / Universidade do Estado do Amazonas. Programa de Pós-Graduação em Medicina Tropical. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Departamento de Ensino e Pesquisa. Manaus, AM, Brasil / Fundação Oswaldo Cruz. Instituto de Pesquisas Leônidas e Maria Deane. Manaus, AM, Brasil.engSociedade Brasileira de Medicina TropicalCOVID-19ChloroquineEnsaios clínicosPesquisaCoronavírusCOVID-19Clinical trialsChloroquineResearchCoronavirusDriving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/40754/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALClaudioTD_Ribeiro_AndréSiqueira_etal_IOC_2020.pdfClaudioTD_Ribeiro_AndréSiqueira_etal_IOC_2020.pdfapplication/pdf896127https://www.arca.fiocruz.br/bitstream/icict/40754/2/ClaudioTD_Ribeiro_Andr%c3%a9Siqueira_etal_IOC_2020.pdf183ab44694e4dd1a794246ba27c74c25MD52TEXTClaudioTD_Ribeiro_AndréSiqueira_etal_IOC_2020.pdf.txtClaudioTD_Ribeiro_AndréSiqueira_etal_IOC_2020.pdf.txtExtracted texttext/plain11368https://www.arca.fiocruz.br/bitstream/icict/40754/3/ClaudioTD_Ribeiro_Andr%c3%a9Siqueira_etal_IOC_2020.pdf.txtd3f9cd89b3f54e69d655aacf0df9cf30MD53icict/407542020-04-15 15:05:38.604oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352020-04-15T18:05:38Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv	Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes
title	Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes
spellingShingle	Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes Monteiro, Wuelton Marcelo COVID-19 Chloroquine Ensaios clínicos Pesquisa Coronavírus COVID-19 Clinical trials Chloroquine Research Coronavirus
title_short	Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes
title_full	Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes
title_fullStr	Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes
title_full_unstemmed	Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes
title_sort	Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes
author	Monteiro, Wuelton Marcelo
author_facet	Monteiro, Wuelton Marcelo Sousa, Jose Diego Brito Silva, Djane Baía da Melo, Gisely Cardoso de Siqueira, André Machado Val, Fernando Daniel-Ribeiro, Cláudio Tadeu Lacerda, Marcus Vinicius Guimarães
author_role	author
author2	Sousa, Jose Diego Brito Silva, Djane Baía da Melo, Gisely Cardoso de Siqueira, André Machado Val, Fernando Daniel-Ribeiro, Cláudio Tadeu Lacerda, Marcus Vinicius Guimarães
author2_role	author author author author author author author
dc.contributor.author.fl_str_mv	Monteiro, Wuelton Marcelo Sousa, Jose Diego Brito Silva, Djane Baía da Melo, Gisely Cardoso de Siqueira, André Machado Val, Fernando Daniel-Ribeiro, Cláudio Tadeu Lacerda, Marcus Vinicius Guimarães
dc.subject.other.pt_BR.fl_str_mv	COVID-19 Chloroquine Ensaios clínicos Pesquisa Coronavírus
topic	COVID-19 Chloroquine Ensaios clínicos Pesquisa Coronavírus COVID-19 Clinical trials Chloroquine Research Coronavirus
dc.subject.en.pt_BR.fl_str_mv	COVID-19 Clinical trials Chloroquine Research Coronavirus
description	Devido a pandemia mundial do COVID-19, o artigo da revista foi liberado em acesso aberto durante o ano de 2020, visando divulgação e disseminação.
publishDate	2020
dc.date.accessioned.fl_str_mv	2020-04-14T18:55:35Z
dc.date.available.fl_str_mv	2020-04-14T18:55:35Z
dc.date.issued.fl_str_mv	2020
dc.type.status.fl_str_mv	info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv	info:eu-repo/semantics/article
format	article
status_str	publishedVersion
dc.identifier.citation.fl_str_mv	MONTEIRO, Wuelton Marcelo et al. Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes. Revista da Sociedade Brasileria de Medicina Tropical, Uberaba, v. 53, p. 1-3, 2020.
dc.identifier.uri.fl_str_mv	https://www.arca.fiocruz.br/handle/icict/40754
dc.identifier.issn.pt_BR.fl_str_mv	0037-8682
dc.identifier.doi.none.fl_str_mv	10.1590/0037-8682-0155-2020
dc.identifier.eissn.none.fl_str_mv	1678-9849
identifier_str_mv	MONTEIRO, Wuelton Marcelo et al. Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes. Revista da Sociedade Brasileria de Medicina Tropical, Uberaba, v. 53, p. 1-3, 2020. 0037-8682 10.1590/0037-8682-0155-2020 1678-9849
url	https://www.arca.fiocruz.br/handle/icict/40754
dc.language.iso.fl_str_mv	eng
language	eng
dc.rights.driver.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.publisher.none.fl_str_mv	Sociedade Brasileira de Medicina Tropical
publisher.none.fl_str_mv	Sociedade Brasileira de Medicina Tropical
dc.source.none.fl_str_mv	reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ
instname_str	Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str	FIOCRUZ
institution	FIOCRUZ
reponame_str	Repositório Institucional da FIOCRUZ (ARCA)
collection	Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv	https://www.arca.fiocruz.br/bitstream/icict/40754/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/40754/2/ClaudioTD_Ribeiro_Andr%c3%a9Siqueira_etal_IOC_2020.pdf https://www.arca.fiocruz.br/bitstream/icict/40754/3/ClaudioTD_Ribeiro_Andr%c3%a9Siqueira_etal_IOC_2020.pdf.txt
bitstream.checksum.fl_str_mv	5a560609d32a3863062d77ff32785d58 183ab44694e4dd1a794246ba27c74c25 d3f9cd89b3f54e69d655aacf0df9cf30
bitstream.checksumAlgorithm.fl_str_mv	MD5 MD5 MD5
repository.name.fl_str_mv	Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv	repositorio.arca@fiocruz.br
_version_	1798324733527195648

Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes

Registros relacionados