The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study

Detalhes bibliográficos
Autor(a) principal: Cuadros, Diego F.
Data de Publicação: 2022
Outros Autores: Oliveira, Tulio de, Gräf, Tiago, Junqueira, Dennis M., Wilkinson, Eduan, Lemey, Philippe, Bärnighausen, Till, Kim, Hae-Young, Tanser, Frank
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/52093
Resumo: Instituto de Saúde. Instituto de Pesquisa em Saúde da África Sistema de Informação de Vigilância Demográfica e Programa de Intervenção Populacional. Wellcome Trust. Departamento de Ciência da África do Sul e Tecnologia e hospedado pelo sul-africano Conselho de Pesquisa Médica.
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spelling Cuadros, Diego F.Oliveira, Tulio deGräf, TiagoJunqueira, Dennis M.Wilkinson, EduanLemey, PhilippeBärnighausen, TillKim, Hae-YoungTanser, Frank2022-04-07T17:24:40Z2022-04-07T17:24:40Z2022CUADROS, Diego F. et al. The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study. PLOS Global Public Health, v. 2, n. 2, 2022.2767-3375https://www.arca.fiocruz.br/handle/icict/5209310.1371/journal.pgph.0000105Instituto de Saúde. Instituto de Pesquisa em Saúde da África Sistema de Informação de Vigilância Demográfica e Programa de Intervenção Populacional. Wellcome Trust. Departamento de Ciência da África do Sul e Tecnologia e hospedado pelo sul-africano Conselho de Pesquisa Médica.Department of Geography and Geographic Information Science. University of Cincinnati. Cincinnati, OH, United States of America / Health Geography and Disease Modeling Laboratory. University of Cincinnati. Cincinnati, OH, United States of America.KwaZulu-Natal Research Innovation and Sequencing Platform. Nelson R Mandela School of Medicine. University of KwaZulu-Natal. Durban, South Africa / School of Laboratory Medicine and Medical Science. Department of Health SciencesKwaZulu-Natal Research Innovation and Sequencing Platform. Nelson R Mandela School of Medicine. University of KwaZulu-Natal. Durban, South Africa / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.KwaZulu-Natal Research Innovation and Sequencing Platform. Nelson R Mandela School of Medicine. University of KwaZulu-Natal. Durban, South Africa / School of Laboratory Medicine and Medical Science. Department of Health Sciences. University of KwaZulu-Natal. Durban, South Africa.KwaZulu-Natal Research Innovation and Sequencing Platform. Nelson R Mandela School of Medicine. University of KwaZulu-Natal. Durban, South Africa / School of Laboratory Medicine and Medical Science. Department of Health Sciences. University of KwaZulu-Natal. Durban, South Africa.Department of Microbiology and Immunology. Rega Institute for Medical Research. University of Leuven, Leuven, Belgium.Africa Health Research Institute. University of KwaZulu-Natal. Durban, South Africa / Heidelberg Institute for Public Health. University of Heidelberg. Heidelberg, Germany / Department of Global Health and Population. Harvard T.H. Chan School of Public Health. Boston, MA, United States of America.Africa Health Research Institute. University of KwaZulu-Natal. Durban, South Africa / Department of Population Health. New York University Grossman School of Medicine. New York, NY, United States of America.Africa Health Research Institute. University of KwaZulu-Natal. Durban, South Africa / School of Nursing and Public Health. University of KwaZulu-Natal. Durban, South Africa / Lincoln International Institute for Rural Health. University of Lincoln, Lincoln, United Kingdom / Centre for the AIDS Programme of Research in South Africa. University of KwaZulu-Natal. Durban, South Africa.In this study, we hypothesize that HIV geographical clusters (geospatial areas with significantly higher numbers of HIV positive individuals) can behave as the highly connected nodes in the transmission network. Using data come from one of the most comprehensive demographic surveillance systems in Africa, we found that more than 70% of the HIV transmission links identified were directly connected to an HIV geographical cluster located in a peri-urban area. Moreover, we identified a single central large community of highly connected nodes located within the HIV cluster. This module was composed by nodes highly connected among them, forming a central structure of the network that was also connected with the small sparser modules located outside of the HIV geographical cluster. Our study supports the evidence of the high level of connectivity between HIV geographical high-risk populations and the entire community.engPublic Library of ScienceHIVTransmissão de Doença InfecciosaÁfricaHIVDisease Transmission, InfectiousAfricaVIHTransmisión de Enfermedad InfecciosaÁfricaVIH (Virus de l'Immunodéficience Humaine)Transmission de maladie infectieuseAfriqueThe role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/52093/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALCuadros, Diego F. - The role of high-risk geographies.pdfCuadros, Diego F. - The role of high-risk geographies.pdfapplication/pdf1508185https://www.arca.fiocruz.br/bitstream/icict/52093/2/Cuadros%2c%20Diego%20F.%20-%20The%20role%20of%20high-risk%20geographies.pdff6672a6b9978a2b5272b52b8fbb9bc2bMD52icict/520932023-03-15 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dc.title.pt_BR.fl_str_mv The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study
title The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study
spellingShingle The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study
Cuadros, Diego F.
HIV
Transmissão de Doença Infecciosa
África
HIV
Disease Transmission, Infectious
Africa
VIH
Transmisión de Enfermedad Infecciosa
África
VIH (Virus de l'Immunodéficience Humaine)
Transmission de maladie infectieuse
Afrique
title_short The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study
title_full The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study
title_fullStr The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study
title_full_unstemmed The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study
title_sort The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study
author Cuadros, Diego F.
author_facet Cuadros, Diego F.
Oliveira, Tulio de
Gräf, Tiago
Junqueira, Dennis M.
Wilkinson, Eduan
Lemey, Philippe
Bärnighausen, Till
Kim, Hae-Young
Tanser, Frank
author_role author
author2 Oliveira, Tulio de
Gräf, Tiago
Junqueira, Dennis M.
Wilkinson, Eduan
Lemey, Philippe
Bärnighausen, Till
Kim, Hae-Young
Tanser, Frank
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cuadros, Diego F.
Oliveira, Tulio de
Gräf, Tiago
Junqueira, Dennis M.
Wilkinson, Eduan
Lemey, Philippe
Bärnighausen, Till
Kim, Hae-Young
Tanser, Frank
dc.subject.other.pt_BR.fl_str_mv HIV
Transmissão de Doença Infecciosa
África
topic HIV
Transmissão de Doença Infecciosa
África
HIV
Disease Transmission, Infectious
Africa
VIH
Transmisión de Enfermedad Infecciosa
África
VIH (Virus de l'Immunodéficience Humaine)
Transmission de maladie infectieuse
Afrique
dc.subject.en.pt_BR.fl_str_mv HIV
Disease Transmission, Infectious
Africa
dc.subject.es.pt_BR.fl_str_mv VIH
Transmisión de Enfermedad Infecciosa
África
dc.subject.fr.pt_BR.fl_str_mv VIH (Virus de l'Immunodéficience Humaine)
Transmission de maladie infectieuse
Afrique
description Instituto de Saúde. Instituto de Pesquisa em Saúde da África Sistema de Informação de Vigilância Demográfica e Programa de Intervenção Populacional. Wellcome Trust. Departamento de Ciência da África do Sul e Tecnologia e hospedado pelo sul-africano Conselho de Pesquisa Médica.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-04-07T17:24:40Z
dc.date.available.fl_str_mv 2022-04-07T17:24:40Z
dc.date.issued.fl_str_mv 2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv CUADROS, Diego F. et al. The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study. PLOS Global Public Health, v. 2, n. 2, 2022.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/52093
dc.identifier.issn.pt_BR.fl_str_mv 2767-3375
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pgph.0000105
identifier_str_mv CUADROS, Diego F. et al. The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: a spatial molecular epidemiology study. PLOS Global Public Health, v. 2, n. 2, 2022.
2767-3375
10.1371/journal.pgph.0000105
url https://www.arca.fiocruz.br/handle/icict/52093
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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