High interleukin 17 expression is correlated with better cardiac function in human Chagas disease

Detalhes bibliográficos
Autor(a) principal: Magalhães, Luisa Mourao Dias
Data de Publicação: 2013
Outros Autores: Villani, Fernanda Nobre Amaral, Nunes, Maria do Carmo Pereira, Gollob, Kenneth John, Rocha, Manoel Otavio da Costa, Dutra, Walderez Ornelas
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/30683
Resumo: 2020-01-01
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spelling Magalhães, Luisa Mourao DiasVillani, Fernanda Nobre AmaralNunes, Maria do Carmo PereiraGollob, Kenneth JohnRocha, Manoel Otavio da CostaDutra, Walderez Ornelas2018-12-18T18:38:50Z2018-12-18T18:38:50Z2013MAGALHÃES, Luisa Mourao Dias et al. High interleukin 17 expression is correlated with better cardiac function in human Chagas disease. J Infect Dis., v. 207, n. 4, p. 661-665, 20130022-1899https://www.arca.fiocruz.br/handle/icict/3068310.1093/infdis/jis724engOxford University PresscardiomiopatiaChagas diseaseIL-17imunoregulaçãopatologiaT. cruziTh17cardiomyopathydoença de chagasIL-17immunoregulationpathology;T. cruziTh17High interleukin 17 expression is correlated with better cardiac function in human Chagas diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-01-01Universidade Federal de Minas Gerais. Instituto de Ciências Biologicas. Departamento de Morphologia. Laboratorio de Interação Celular. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Instituto de Ciências Biologicas. Departamento de Morphologia. Laboratorio de Interação Celular. Belo Horizonte, MG, Brasil/ Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Doenças Infecciosas e Medicina Tropical. Belo Horizonte, MG, BrasilHospital Santa Casa. Belo Horizonte, MG, Brasil/Instituto Nacional de Ciência e Tecnologia e Doenças Tropicais. Belo Horizonte, MG, Brasil/Global Health Program, Center for Infectious Disease Research, SRI International, Menlo Park, CaliforniaUniversidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Doenças Infecciosas e Medicina Tropical. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Instituto de Ciências Biologicas. Departamento de Morphologia. Laboratorio de Interação Celular. Belo Horizonte, MG, Brasil/Instituto Nacional de Ciência e Tecnologia e Doenças Tropicais. Belo Horizonte, MG, Brasil/Global Health Program, Center for Infectious Disease Research, SRI International, Menlo Park, CaliforniaThis study was designed to investigate whether the expression of interleukin 17 (IL-17) is associated with the indeterminate or cardiac clinical forms of Chagas disease and whether IL-17 expression can be correlated with patients’ cardiac function. Our results demonstrated that cardiac Chagas patients have a lower intensity of expression of IL-17 by total lymphocytes and lower frequency of circulating T helper 17 cells. Correlative analysis showed that high IL-17 expression was associated with better cardiac function, as determined by left ventricular ejection fraction and left ventricular diastolic diameter values. Therefore, IL-17 expression can be a protective factor to prevent myocardial damage in human Chagas disease.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/30683/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALHigh Interleukin 17 Expression Is Correlated With Better Cardiac.pdfHigh Interleukin 17 Expression Is Correlated With Better Cardiac.pdfapplication/pdf2523867https://www.arca.fiocruz.br/bitstream/icict/30683/2/High%20Interleukin%2017%20Expression%20Is%20Correlated%20With%20Better%20Cardiac.pdf8632f0a8b6819ffb85414024de7364b5MD52TEXTHigh Interleukin 17 Expression Is Correlated With Better Cardiac.pdf.txtHigh Interleukin 17 Expression Is Correlated With Better Cardiac.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv High interleukin 17 expression is correlated with better cardiac function in human Chagas disease
title High interleukin 17 expression is correlated with better cardiac function in human Chagas disease
spellingShingle High interleukin 17 expression is correlated with better cardiac function in human Chagas disease
Magalhães, Luisa Mourao Dias
cardiomiopatia
Chagas disease
IL-17
imunoregulação
patologia
T. cruzi
Th17
cardiomyopathy
doença de chagas
IL-17
immunoregulation
pathology;
T. cruzi
Th17
title_short High interleukin 17 expression is correlated with better cardiac function in human Chagas disease
title_full High interleukin 17 expression is correlated with better cardiac function in human Chagas disease
title_fullStr High interleukin 17 expression is correlated with better cardiac function in human Chagas disease
title_full_unstemmed High interleukin 17 expression is correlated with better cardiac function in human Chagas disease
title_sort High interleukin 17 expression is correlated with better cardiac function in human Chagas disease
author Magalhães, Luisa Mourao Dias
author_facet Magalhães, Luisa Mourao Dias
Villani, Fernanda Nobre Amaral
Nunes, Maria do Carmo Pereira
Gollob, Kenneth John
Rocha, Manoel Otavio da Costa
Dutra, Walderez Ornelas
author_role author
author2 Villani, Fernanda Nobre Amaral
Nunes, Maria do Carmo Pereira
Gollob, Kenneth John
Rocha, Manoel Otavio da Costa
Dutra, Walderez Ornelas
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Magalhães, Luisa Mourao Dias
Villani, Fernanda Nobre Amaral
Nunes, Maria do Carmo Pereira
Gollob, Kenneth John
Rocha, Manoel Otavio da Costa
Dutra, Walderez Ornelas
dc.subject.other.pt_BR.fl_str_mv cardiomiopatia
Chagas disease
IL-17
imunoregulação
patologia
T. cruzi
Th17
topic cardiomiopatia
Chagas disease
IL-17
imunoregulação
patologia
T. cruzi
Th17
cardiomyopathy
doença de chagas
IL-17
immunoregulation
pathology;
T. cruzi
Th17
dc.subject.en.pt_BR.fl_str_mv cardiomyopathy
doença de chagas
IL-17
immunoregulation
pathology;
T. cruzi
Th17
description 2020-01-01
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2018-12-18T18:38:50Z
dc.date.available.fl_str_mv 2018-12-18T18:38:50Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MAGALHÃES, Luisa Mourao Dias et al. High interleukin 17 expression is correlated with better cardiac function in human Chagas disease. J Infect Dis., v. 207, n. 4, p. 661-665, 2013
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/30683
dc.identifier.issn.pt_BR.fl_str_mv 0022-1899
dc.identifier.doi.none.fl_str_mv 10.1093/infdis/jis724
identifier_str_mv MAGALHÃES, Luisa Mourao Dias et al. High interleukin 17 expression is correlated with better cardiac function in human Chagas disease. J Infect Dis., v. 207, n. 4, p. 661-665, 2013
0022-1899
10.1093/infdis/jis724
url https://www.arca.fiocruz.br/handle/icict/30683
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/30683/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/30683/2/High%20Interleukin%2017%20Expression%20Is%20Correlated%20With%20Better%20Cardiac.pdf
https://www.arca.fiocruz.br/bitstream/icict/30683/3/High%20Interleukin%2017%20Expression%20Is%20Correlated%20With%20Better%20Cardiac.pdf.txt
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