Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2016 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/22818 |
Resumo: | HHS National Institutes of Health (NIH) (R01-HL105704 and R21-AI120977). This work, including the efforts of Charles Y. Chiu, was funded by Abbott Laboratories. |
| id |
CRUZ_134cbfcfbac271f0f7f91d7df89fca17 |
|---|---|
| oai_identifier_str |
oai:www.arca.fiocruz.br:icict/22818 |
| network_acronym_str |
CRUZ |
| network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| repository_id_str |
2135 |
| spelling |
Sardi, Silvia InesSomasekar, SnehaNaccache, Samia N.Bandeira, Antonio Carlos de AlbuquerqueTauro, Laura BeatrizCampos, Gubio SoaresChiu, Charles Y2017-10-10T16:44:17Z2017-10-10T16:44:17Z2016SARDI, Silvia Ines et al. Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing. Journal of Clinical Microbiology, v. 54, n. 9, p. 2348-2353, 2016.0095-1137https://www.arca.fiocruz.br/handle/icict/2281810.1128/JCM.00877-16HHS National Institutes of Health (NIH) (R01-HL105704 and R21-AI120977). This work, including the efforts of Charles Y. Chiu, was funded by Abbott Laboratories.University Federal of Bahia. Health Institute of Science. Laboratory of Virology. Salvador, BA, Brazil.University of California. Department of Laboratory Medicine. San Francisco, California, USA / UCSF-Abbott Viral Diagnostics and Discovery Center. San Francisco, CA, USA.University of California. Department of Laboratory Medicine. San Francisco, California, USA / UCSF-Abbott Viral Diagnostics and Discovery Center. San Francisco, CA, USA.Aliança Hospital. Salvador, BA, Brazil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.University Federal of Bahia. Health Institute of Science. Laboratory of Virology. Salvador, BA, Brazil.University of California. Department of Laboratory Medicine. San Francisco, CA, USA / UCSF-Abbott Viral Diagnostics and Discovery Center. San Francisco, CA, USA / University of California,. Department of Medicine, Division of Infectious Diseases. San Francisco, CA, USA.Metagenomic next-generation sequencing (mNGS) of samples from 15 patients with documented Zika virus (ZIKV) infection in Bahia, Brazil, from April 2015 to January 2016 identified coinfections with chikungunya virus (CHIKV) in 2 of 15 ZIKV-positive cases by PCR (13.3%). While generally nonspecific, the clinical presentation corresponding to these two CHIKV/ZIKV coinfections reflected infection by the virus present at a higher titer. Aside from CHIKV and ZIKV, coinfections of other viral pathogens were not detected. The mNGS approach is promising for differential diagnosis of acute febrile illness and identification of coinfections, although targeted arbovirus screening may be sufficient in the current ZIKV outbreak setting.engAmerican Society for MicrobiologyVirus ZikaInfecção por vírus ZikaFebre ChikungunyaVirus ChikungunyaInfecçãoMetagenômicaHumanosAdultoBrasilZika VirusZika Virus InfectionChikungunya FeverChikungunya virusCoinfectionMetagenomicsHumansAdultBrazilCoinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencinginfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/22818/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALSardi SI Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil....pdfSardi SI Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil....pdfapplication/pdf2662780https://www.arca.fiocruz.br/bitstream/icict/22818/2/Sardi%20SI%20Coinfections%20of%20Zika%20and%20Chikungunya%20Viruses%20in%20Bahia%2c%20Brazil....pdf2a4cc2fe8855a267b29792428b2c6d17MD52TEXTSardi SI Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil....pdf.txtSardi SI Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil....pdf.txtExtracted texttext/plain33624https://www.arca.fiocruz.br/bitstream/icict/22818/3/Sardi%20SI%20Coinfections%20of%20Zika%20and%20Chikungunya%20Viruses%20in%20Bahia%2c%20Brazil....pdf.txt45c8f9f00b724ff80566dfd4a63ba5a2MD53icict/228182023-03-15 14:33:53.633oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:53Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing |
| title |
Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing |
| spellingShingle |
Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing Sardi, Silvia Ines Virus Zika Infecção por vírus Zika Febre Chikungunya Virus Chikungunya Infecção Metagenômica Humanos Adulto Brasil Zika Virus Zika Virus Infection Chikungunya Fever Chikungunya virus Coinfection Metagenomics Humans Adult Brazil |
| title_short |
Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing |
| title_full |
Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing |
| title_fullStr |
Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing |
| title_full_unstemmed |
Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing |
| title_sort |
Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing |
| author |
Sardi, Silvia Ines |
| author_facet |
Sardi, Silvia Ines Somasekar, Sneha Naccache, Samia N. Bandeira, Antonio Carlos de Albuquerque Tauro, Laura Beatriz Campos, Gubio Soares Chiu, Charles Y |
| author_role |
author |
| author2 |
Somasekar, Sneha Naccache, Samia N. Bandeira, Antonio Carlos de Albuquerque Tauro, Laura Beatriz Campos, Gubio Soares Chiu, Charles Y |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Sardi, Silvia Ines Somasekar, Sneha Naccache, Samia N. Bandeira, Antonio Carlos de Albuquerque Tauro, Laura Beatriz Campos, Gubio Soares Chiu, Charles Y |
| dc.subject.other.pt_BR.fl_str_mv |
Virus Zika Infecção por vírus Zika Febre Chikungunya Virus Chikungunya Infecção Metagenômica Humanos Adulto Brasil |
| topic |
Virus Zika Infecção por vírus Zika Febre Chikungunya Virus Chikungunya Infecção Metagenômica Humanos Adulto Brasil Zika Virus Zika Virus Infection Chikungunya Fever Chikungunya virus Coinfection Metagenomics Humans Adult Brazil |
| dc.subject.en.pt_BR.fl_str_mv |
Zika Virus Zika Virus Infection Chikungunya Fever Chikungunya virus Coinfection Metagenomics Humans Adult Brazil |
| description |
HHS National Institutes of Health (NIH) (R01-HL105704 and R21-AI120977). This work, including the efforts of Charles Y. Chiu, was funded by Abbott Laboratories. |
| publishDate |
2016 |
| dc.date.issued.fl_str_mv |
2016 |
| dc.date.accessioned.fl_str_mv |
2017-10-10T16:44:17Z |
| dc.date.available.fl_str_mv |
2017-10-10T16:44:17Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
SARDI, Silvia Ines et al. Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing. Journal of Clinical Microbiology, v. 54, n. 9, p. 2348-2353, 2016. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/22818 |
| dc.identifier.issn.pt_BR.fl_str_mv |
0095-1137 |
| dc.identifier.doi.none.fl_str_mv |
10.1128/JCM.00877-16 |
| identifier_str_mv |
SARDI, Silvia Ines et al. Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing. Journal of Clinical Microbiology, v. 54, n. 9, p. 2348-2353, 2016. 0095-1137 10.1128/JCM.00877-16 |
| url |
https://www.arca.fiocruz.br/handle/icict/22818 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
American Society for Microbiology |
| publisher.none.fl_str_mv |
American Society for Microbiology |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
| instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
| reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/22818/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/22818/2/Sardi%20SI%20Coinfections%20of%20Zika%20and%20Chikungunya%20Viruses%20in%20Bahia%2c%20Brazil....pdf https://www.arca.fiocruz.br/bitstream/icict/22818/3/Sardi%20SI%20Coinfections%20of%20Zika%20and%20Chikungunya%20Viruses%20in%20Bahia%2c%20Brazil....pdf.txt |
| bitstream.checksum.fl_str_mv |
5a560609d32a3863062d77ff32785d58 2a4cc2fe8855a267b29792428b2c6d17 45c8f9f00b724ff80566dfd4a63ba5a2 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1813008971021156352 |