XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis

Detalhes bibliográficos
Autor(a) principal: Boons, Eline
Data de Publicação: 2021
Outros Autores: Nogueira, Tatiane C., Dierckx, Tim, Menezes, Soraya Maria, Jacquemyn, Maarten, Tamir, Sharon, Landesman, Yosef, Vallve, Maria Lourdes Farré, Bittencourt, Achiléa Lisboa Candido, Kataoka, Keisuke, Ogawa, Seishi, Snoeck, Robert, Andrei, Graciela, Van Weyenbergh, Johan, Daelemans, Dirk
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/48626
Resumo: Vallve, Maria Lourdes Farré. Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. 1KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000 Leuven, Belgium. 2KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute, B-3000 Leuven, Belgium. 3Karyopharm Therapeutics, Newton, MA, USA. 4Instituto de Pesquisa Goncalo Moniz, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Bahia, Brazil. 5HUPES, Federal University of Bahia (UFBA), Salvador-Bahia, Brazil. 6Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan
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spelling Boons, ElineNogueira, Tatiane C.Dierckx, TimMenezes, Soraya MariaJacquemyn, MaartenTamir, SharonLandesman, YosefVallve, Maria Lourdes FarréBittencourt, Achiléa Lisboa CandidoKataoka, KeisukeOgawa, SeishiSnoeck, RobertAndrei, GracielaVan Weyenbergh, JohanDaelemans, Dirk2021-08-16T11:34:47Z2021-08-16T11:34:47Z2021BOONS, Eline et al. XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis. Blood Cancer Journal, v. 11, p. 1-5, 2021.2044-5385https://www.arca.fiocruz.br/handle/icict/4862610.1038/s41408-021-00409-310.1038/s41408-021-00409-3Vallve, Maria Lourdes Farré. Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. 1KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000 Leuven, Belgium. 2KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute, B-3000 Leuven, Belgium. 3Karyopharm Therapeutics, Newton, MA, USA. 4Instituto de Pesquisa Goncalo Moniz, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Bahia, Brazil. 5HUPES, Federal University of Bahia (UFBA), Salvador-Bahia, Brazil. 6Department of Pathology and Tumor Biology, Kyoto University, Kyoto, JapanFWO (grant G0D6817N) and KU Leuven (“Vaast Leysen Leerstoel voor Infectieziekten in Ontwikkelingslanden”). S.O. is supported by Grant-in-Aid from the Japan Agency for Medical Research and Development [JP119cm0106501h0004, JP119cm0106501h0004], Grant-in-Aid for Scientific Research (KAKENHI 15H05909).KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000. Leuven, Belgium.KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000. Leuven, Belgium.KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute, B-3000. Leuven, Belgium.KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute, B-3000. Leuven, Belgium.KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000. Leuven, Belgium.Karyopharm Therapeutics. Newton, MA, USA.Karyopharm Therapeutics. Newton, MA, USA.Oswaldo Cruz Foundation. Instituto de Pesquisa Gonçalo Moniz. Salvador, BA, Brazil.Federal University of Bahia. HUPES. Salvador, BA, Brazil.Kyoto University. Department of Pathology and Tumor Biology. Kyoto, Japan. .Kyoto University. Department of Pathology and Tumor Biology. Kyoto, Japan.KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000. Leuven, Belgium.KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000. Leuven, Belgium.KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute, B-3000. Leuven, Belgium.KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000. Leuven, Belgium.engSpringer NatureLeucemia de Células TLinfoma Difuso de Grandes Células BNeoplasiasVírus Linfotrópico T Tipo 1 HumanoLeukemia, TCellLymphoma, Large B-Cell, DiffuseNeoplasmsHuman T-lymphotropic virus 1XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/48626/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALBoons, Eline XPO1 inhibitors....pdfBoons, Eline XPO1 inhibitors....pdfapplication/pdf666820https://www.arca.fiocruz.br/bitstream/icict/48626/2/Boons%2c%20Eline%20XPO1%20inhibitors....pdf85bcca182536fc847f6abab4bdeab1a3MD52TEXTBoons, Eline XPO1 inhibitors....pdf.txtBoons, 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dc.title.pt_BR.fl_str_mv XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis
title XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis
spellingShingle XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis
Boons, Eline
Leucemia de Células T
Linfoma Difuso de Grandes Células B
Neoplasias
Vírus Linfotrópico T Tipo 1 Humano
Leukemia, TCell
Lymphoma, Large B-Cell, Diffuse
Neoplasms
Human T-lymphotropic virus 1
title_short XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis
title_full XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis
title_fullStr XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis
title_full_unstemmed XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis
title_sort XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis
author Boons, Eline
author_facet Boons, Eline
Nogueira, Tatiane C.
Dierckx, Tim
Menezes, Soraya Maria
Jacquemyn, Maarten
Tamir, Sharon
Landesman, Yosef
Vallve, Maria Lourdes Farré
Bittencourt, Achiléa Lisboa Candido
Kataoka, Keisuke
Ogawa, Seishi
Snoeck, Robert
Andrei, Graciela
Van Weyenbergh, Johan
Daelemans, Dirk
author_role author
author2 Nogueira, Tatiane C.
Dierckx, Tim
Menezes, Soraya Maria
Jacquemyn, Maarten
Tamir, Sharon
Landesman, Yosef
Vallve, Maria Lourdes Farré
Bittencourt, Achiléa Lisboa Candido
Kataoka, Keisuke
Ogawa, Seishi
Snoeck, Robert
Andrei, Graciela
Van Weyenbergh, Johan
Daelemans, Dirk
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Boons, Eline
Nogueira, Tatiane C.
Dierckx, Tim
Menezes, Soraya Maria
Jacquemyn, Maarten
Tamir, Sharon
Landesman, Yosef
Vallve, Maria Lourdes Farré
Bittencourt, Achiléa Lisboa Candido
Kataoka, Keisuke
Ogawa, Seishi
Snoeck, Robert
Andrei, Graciela
Van Weyenbergh, Johan
Daelemans, Dirk
dc.subject.other.pt_BR.fl_str_mv Leucemia de Células T
Linfoma Difuso de Grandes Células B
Neoplasias
Vírus Linfotrópico T Tipo 1 Humano
topic Leucemia de Células T
Linfoma Difuso de Grandes Células B
Neoplasias
Vírus Linfotrópico T Tipo 1 Humano
Leukemia, TCell
Lymphoma, Large B-Cell, Diffuse
Neoplasms
Human T-lymphotropic virus 1
dc.subject.en.pt_BR.fl_str_mv Leukemia, TCell
Lymphoma, Large B-Cell, Diffuse
Neoplasms
Human T-lymphotropic virus 1
description Vallve, Maria Lourdes Farré. Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. 1KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000 Leuven, Belgium. 2KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute, B-3000 Leuven, Belgium. 3Karyopharm Therapeutics, Newton, MA, USA. 4Instituto de Pesquisa Goncalo Moniz, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Bahia, Brazil. 5HUPES, Federal University of Bahia (UFBA), Salvador-Bahia, Brazil. 6Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-08-16T11:34:47Z
dc.date.available.fl_str_mv 2021-08-16T11:34:47Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv BOONS, Eline et al. XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis. Blood Cancer Journal, v. 11, p. 1-5, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/48626
dc.identifier.issn.pt_BR.fl_str_mv 2044-5385
dc.identifier.doi.pt_BR.fl_str_mv 10.1038/s41408-021-00409-3
dc.identifier.eissn.none.fl_str_mv 10.1038/s41408-021-00409-3
identifier_str_mv BOONS, Eline et al. XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53- mediated caspase-dependent apoptosis. Blood Cancer Journal, v. 11, p. 1-5, 2021.
2044-5385
10.1038/s41408-021-00409-3
url https://www.arca.fiocruz.br/handle/icict/48626
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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