Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2014 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/10411 |
Resumo: | Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. |
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Kozlowski, Aline GarciaCarneiro, Megmar Aparecida dos SantosMatos, Márcia Alves Dias deTeles, Sheila AraújoAraújo Filho, João AlvesOtsuki, KokoVicente, Ana Carolina PauloMartins, Regina Maria Bringel2015-05-19T13:26:08Z2015-05-19T13:26:08Z2014KOZLOWSKI, Aline Garcia et al. Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil. Mem Inst Oswaldo Cruz,v.109, n.1, p.118-121, Feb. 2014.1678-8060https://www.arca.fiocruz.br/handle/icict/1041110.1590/0074-0276130230engFundação Oswaldo CruzPrevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInstituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil .Universidade Federal de Goiás. Faculdade de Enfermagem. Goiânia, GO, Brasil.Instituto de Patologia Tropical e Saúde Pública / Hospital de Doenças Tropicais Anuar Auad. Goiânia, GO, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil .Human T-cell lymphotropic virus (HTLV) may impact the clinical course of tuberculosis (TB). Both infections are highly endemic in Brazil. The aim of this study was to assess the prevalence of HTLV-1/2 in TB patients in Central-West Brazil and to perform a genetic characterisation of the respective isolates. Of the 402 patients, six (1.49%) were positive for anti-HTLV and five (1.24%; 95% confidence interval: 0.46-3.05) were infected with HTLV-1/2. Genetic characterisation demonstrated that the four HTLV-1 isolates belonged to the Transcontinental subgroup A of the Cosmopolitan subtype a and that the HTLV-2 isolate belonged to subtype a (HTLV-2a/c). The prevalence of HTLV infection observed in this study is higher than that observed in local blood donors and the HTLV-1 and 2 subtypes identified are consistent with those circulating in Brazil.HTLV-1HTLV-2TuberculosisPrevalencePrevalênciaTuberculoseinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/10411/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALkoko_otsukietal_IOC_2014.pdfapplication/pdf295584https://www.arca.fiocruz.br/bitstream/icict/10411/2/koko_otsukietal_IOC_2014.pdfc1afb54601113dbadea5046dca7e1038MD52TEXTkoko_otsukietal_IOC_2014.pdf.txtkoko_otsukietal_IOC_2014.pdf.txtExtracted texttext/plain19390https://www.arca.fiocruz.br/bitstream/icict/10411/3/koko_otsukietal_IOC_2014.pdf.txtb34e5cb716127850e77b147ef5ee74a0MD53icict/104112022-06-24 12:19:33.793oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T15:19:33Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil |
| title |
Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil |
| spellingShingle |
Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil Kozlowski, Aline Garcia HTLV-1 HTLV-2 Tuberculosis Prevalence Prevalência Tuberculose |
| title_short |
Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil |
| title_full |
Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil |
| title_fullStr |
Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil |
| title_full_unstemmed |
Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil |
| title_sort |
Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil |
| author |
Kozlowski, Aline Garcia |
| author_facet |
Kozlowski, Aline Garcia Carneiro, Megmar Aparecida dos Santos Matos, Márcia Alves Dias de Teles, Sheila Araújo Araújo Filho, João Alves Otsuki, Koko Vicente, Ana Carolina Paulo Martins, Regina Maria Bringel |
| author_role |
author |
| author2 |
Carneiro, Megmar Aparecida dos Santos Matos, Márcia Alves Dias de Teles, Sheila Araújo Araújo Filho, João Alves Otsuki, Koko Vicente, Ana Carolina Paulo Martins, Regina Maria Bringel |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Kozlowski, Aline Garcia Carneiro, Megmar Aparecida dos Santos Matos, Márcia Alves Dias de Teles, Sheila Araújo Araújo Filho, João Alves Otsuki, Koko Vicente, Ana Carolina Paulo Martins, Regina Maria Bringel |
| dc.subject.en.pt_BR.fl_str_mv |
HTLV-1 HTLV-2 Tuberculosis Prevalence |
| topic |
HTLV-1 HTLV-2 Tuberculosis Prevalence Prevalência Tuberculose |
| dc.subject.decs.pt_BR.fl_str_mv |
Prevalência Tuberculose |
| description |
Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. |
| publishDate |
2014 |
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2014 |
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2015-05-19T13:26:08Z |
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2015-05-19T13:26:08Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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KOZLOWSKI, Aline Garcia et al. Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil. Mem Inst Oswaldo Cruz,v.109, n.1, p.118-121, Feb. 2014. |
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https://www.arca.fiocruz.br/handle/icict/10411 |
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1678-8060 |
| dc.identifier.doi.pt_BR.fl_str_mv |
10.1590/0074-0276130230 |
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KOZLOWSKI, Aline Garcia et al. Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil. Mem Inst Oswaldo Cruz,v.109, n.1, p.118-121, Feb. 2014. 1678-8060 10.1590/0074-0276130230 |
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