The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation

Detalhes bibliográficos
Autor(a) principal: Bitencourt, Tamires A.
Data de Publicação: 2022
Outros Autores: Pessoni, André M., Oliveira, Bianca T. M., Alves, Lysangela Ronalte, Almeida, Fausto
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/54831
Resumo: Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Bioquímica e Imunologia. Ribeirão Preto, SP, Brasil.
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spelling Bitencourt, Tamires A.Pessoni, André M.Oliveira, Bianca T. M.Alves, Lysangela RonalteAlmeida, Fausto2022-09-21T17:18:49Z2022-09-21T17:18:49Z2022BITENCOURT, Tamires A. et al. The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation. Cells, v. 11, n. 2184, p. 1–11, 2022.2073-4409https://www.arca.fiocruz.br/handle/icict/5483110.3390/ cells11142184porMDPIMicosesRNAVias de SinalizaçãoMycosesSignal TransductionExtracellular VesiclesMicosisARNTransducción de SeñalVesículas ExtracelularesVésicules extracellulairesInfecções FúngicasÁcido RibonucleicoTransdução de SinaisVesículas ExtracelularesThe RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Bioquímica e Imunologia. Ribeirão Preto, SP, Brasil.Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Bioquímica e Imunologia. Ribeirão Preto, SP, Brasil.Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Bioquímica e Imunologia. Ribeirão Preto, SP, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Regulação da Expressão Gênica. Curitiba, PR, Brasil.Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Bioquímica e Imunologia. Ribeirão Preto, SP, Brasil.The role of extracellular vesicles (EVs) in interkingdom communication is widely accepted, and their role in intraspecies communication has been strengthened by recent research. Based on the regulation promoted by EV-associated molecules, the interactions between host and pathogens can reveal different pathways that ultimately affect infection outcomes. As a great part of the regulation is ascribable to RNA contained in EVs, many studies have focused on profiling RNAs in fungal and host EVs, tracking their accumulation during infection, and identifying potential target genes. Herein, we overview the main classes of RNA contained in fungal EVs and the biological processes regulated by these molecules, portraying a state-of-the-art picture of RNAs loaded in fungal EVs, while also raising several questions to drive future investigations. Our compiled data show unambiguously that EVs act as key elements in signaling pathways, and play a crucial role in pathosystems. A complete understanding of the processes that govern RNA content loading and trafficking, and its effect on recipient cells, will lead to improved technologies to ward off infectious agents that threaten human health.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83084https://www.arca.fiocruz.br/bitstream/icict/54831/1/license.txt783568c2893d2e25a99990b126be1772MD51ORIGINALcells-11-02184OK.pdfcells-11-02184OK.pdfapplication/pdf2453818https://www.arca.fiocruz.br/bitstream/icict/54831/2/cells-11-02184OK.pdfc20b2213586c068707a3c998246018adMD52icict/548312022-09-21 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dc.title.en_US.fl_str_mv The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation
title The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation
spellingShingle The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation
Bitencourt, Tamires A.
Micoses
RNA
Vias de Sinalização
Mycoses
Signal Transduction
Extracellular Vesicles
Micosis
ARN
Transducción de Señal
Vesículas Extracelulares
Vésicules extracellulaires
Infecções Fúngicas
Ácido Ribonucleico
Transdução de Sinais
Vesículas Extracelulares
title_short The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation
title_full The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation
title_fullStr The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation
title_full_unstemmed The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation
title_sort The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation
author Bitencourt, Tamires A.
author_facet Bitencourt, Tamires A.
Pessoni, André M.
Oliveira, Bianca T. M.
Alves, Lysangela Ronalte
Almeida, Fausto
author_role author
author2 Pessoni, André M.
Oliveira, Bianca T. M.
Alves, Lysangela Ronalte
Almeida, Fausto
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Bitencourt, Tamires A.
Pessoni, André M.
Oliveira, Bianca T. M.
Alves, Lysangela Ronalte
Almeida, Fausto
dc.subject.other.en_US.fl_str_mv Micoses
RNA
Vias de Sinalização
topic Micoses
RNA
Vias de Sinalização
Mycoses
Signal Transduction
Extracellular Vesicles
Micosis
ARN
Transducción de Señal
Vesículas Extracelulares
Vésicules extracellulaires
Infecções Fúngicas
Ácido Ribonucleico
Transdução de Sinais
Vesículas Extracelulares
dc.subject.en.en_US.fl_str_mv Mycoses
Signal Transduction
Extracellular Vesicles
dc.subject.es.en_US.fl_str_mv Micosis
ARN
Transducción de Señal
Vesículas Extracelulares
dc.subject.fr.en_US.fl_str_mv Vésicules extracellulaires
dc.subject.decs.en_US.fl_str_mv Infecções Fúngicas
Ácido Ribonucleico
Transdução de Sinais
Vesículas Extracelulares
description Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Bioquímica e Imunologia. Ribeirão Preto, SP, Brasil.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-09-21T17:18:49Z
dc.date.available.fl_str_mv 2022-09-21T17:18:49Z
dc.date.issued.fl_str_mv 2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BITENCOURT, Tamires A. et al. The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation. Cells, v. 11, n. 2184, p. 1–11, 2022.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/54831
dc.identifier.issn.en_US.fl_str_mv 2073-4409
dc.identifier.doi.none.fl_str_mv 10.3390/ cells11142184
identifier_str_mv BITENCOURT, Tamires A. et al. The RNA content of fungal extracellular vesicles: at the “cutting-edge” of pathophysiology regulation. Cells, v. 11, n. 2184, p. 1–11, 2022.
2073-4409
10.3390/ cells11142184
url https://www.arca.fiocruz.br/handle/icict/54831
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/54831/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/54831/2/cells-11-02184OK.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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