Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2008 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/28322 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil. |
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Lima Junior, J. C.Tran, T. M.Meyer, E. V. S.Singh, B.De Simone, Salvatore GiovanniSantos, F.Daniel-Ribeiro, Cláudio TadeuMoreno, A.Barnwell, J. W.Galinski, M. R.Ferreira, J. Oliveira2018-08-23T13:18:40Z2018-08-23T13:18:40Z2008LIMA JUNIOR, J. C. et al. Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals. Vaccine, v. 26, n. 51, p. 6645-6654, Dec. 2008.0264-410Xhttps://www.arca.fiocruz.br/handle/icict/2832210.1016/j.vaccine.2008.09.0291873-2518engElsevier 12 MonthsPlasmodium vivaxMaláriaVacinasNoroeste da AmazôniaPlasmodium vivaxMalVaccineMerozoite Surface Protein-9Northwestern AmazonNaturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individualsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil.Emory University. YerkesNational Primate Research Center. Emory Vaccine Center. Atlanta, GA, USA.Emory University. YerkesNational Primate Research Center. Emory Vaccine Center. Atlanta, GA, USA.Emory University. YerkesNational Primate Research Center. Emory Vaccine Center. Atlanta, GA, USA.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica de Proteínas e Peptídeos. Rio de Janeiro, RJ. Brasil / Universidade Federal Fluminense. Instituto de Biologia. Departamento de Bioquímica e Biologia Molecular. Niterói, RJ, Brasil.Laboratório Central de Saúde Pública de Rondônia. Departamento de Entomologia. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil.Emory University. YerkesNational Primate Research Center. Emory Vaccine Center. Atlanta, GA, USA / Emory University School of Medicine. Divisiond of Infectious Disease. Atlanta, GA, USA.Center for Disease Control and Prevention. Division of Parasitic Diseases. Atlanta, GA, USA.Emory University. YerkesNational Primate Research Center. Emory Vaccine Center. Atlanta, GA, USA / Emory University School of Medicine. Divisiond of Infectious Disease. Atlanta, GA, USA.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil.Antibody and T-cell reactivities to Plasmodium vivax merozoite surface protein 9 (PvMSP9) were evaluated in a cross-sectional study of individuals naturally exposed to malaria infections living in Ribeirinha, a native riverine community and in Colina, a transmigrant community, Rondonia, Brazil. The antibody responses to PvMSP9-RIRIIand PvMSP9-Nt domains in Ribeirinha were higher compared with Colina and correlated with age and time of malaria exposure. IgG2 was most prevalent for PvMSP9-RII in both communities, and IgG1 was the predominant isotype for PvMSP9-Nt and PvMSP9-RIRII in Ribeirinha. IFN-gamma and IL-4 predominated in Ribeirinha, while IFN-gamma predominated in Colina. Variation in exposure to P. vivax likely accounts for the differences observed in cytokine and antibody levels between the two populations studied.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/28322/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALJC_limajunior_etal_IOC_2008.pdfJC_limajunior_etal_IOC_2008.pdfapplication/pdf808681https://www.arca.fiocruz.br/bitstream/icict/28322/2/JC_limajunior_etal_IOC_2008.pdf2ce00e33f61c6c699d5c206955fa3bc1MD52TEXTJC_limajunior_etal_IOC_2008.pdf.txtJC_limajunior_etal_IOC_2008.pdf.txtExtracted texttext/plain67157https://www.arca.fiocruz.br/bitstream/icict/28322/3/JC_limajunior_etal_IOC_2008.pdf.txt24b63f8b4cdf56e32a5e3d9499277034MD53icict/283222019-01-10 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| dc.title.pt_BR.fl_str_mv |
Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals |
| title |
Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals |
| spellingShingle |
Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals Lima Junior, J. C. Plasmodium vivax Malária Vacinas Noroeste da Amazônia Plasmodium vivax Mal Vaccine Merozoite Surface Protein-9 Northwestern Amazon |
| title_short |
Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals |
| title_full |
Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals |
| title_fullStr |
Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals |
| title_full_unstemmed |
Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals |
| title_sort |
Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals |
| author |
Lima Junior, J. C. |
| author_facet |
Lima Junior, J. C. Tran, T. M. Meyer, E. V. S. Singh, B. De Simone, Salvatore Giovanni Santos, F. Daniel-Ribeiro, Cláudio Tadeu Moreno, A. Barnwell, J. W. Galinski, M. R. Ferreira, J. Oliveira |
| author_role |
author |
| author2 |
Tran, T. M. Meyer, E. V. S. Singh, B. De Simone, Salvatore Giovanni Santos, F. Daniel-Ribeiro, Cláudio Tadeu Moreno, A. Barnwell, J. W. Galinski, M. R. Ferreira, J. Oliveira |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Lima Junior, J. C. Tran, T. M. Meyer, E. V. S. Singh, B. De Simone, Salvatore Giovanni Santos, F. Daniel-Ribeiro, Cláudio Tadeu Moreno, A. Barnwell, J. W. Galinski, M. R. Ferreira, J. Oliveira |
| dc.subject.other.pt_BR.fl_str_mv |
Plasmodium vivax Malária Vacinas Noroeste da Amazônia |
| topic |
Plasmodium vivax Malária Vacinas Noroeste da Amazônia Plasmodium vivax Mal Vaccine Merozoite Surface Protein-9 Northwestern Amazon |
| dc.subject.en.pt_BR.fl_str_mv |
Plasmodium vivax Mal Vaccine Merozoite Surface Protein-9 Northwestern Amazon |
| description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil. |
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2008 |
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2008 |
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2018-08-23T13:18:40Z |
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2018-08-23T13:18:40Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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LIMA JUNIOR, J. C. et al. Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals. Vaccine, v. 26, n. 51, p. 6645-6654, Dec. 2008. |
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https://www.arca.fiocruz.br/handle/icict/28322 |
| dc.identifier.issn.pt_BR.fl_str_mv |
0264-410X |
| dc.identifier.doi.none.fl_str_mv |
10.1016/j.vaccine.2008.09.029 |
| dc.identifier.eissn.none.fl_str_mv |
1873-2518 |
| identifier_str_mv |
LIMA JUNIOR, J. C. et al. Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals. Vaccine, v. 26, n. 51, p. 6645-6654, Dec. 2008. 0264-410X 10.1016/j.vaccine.2008.09.029 1873-2518 |
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Elsevier 12 Months |
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Elsevier 12 Months |
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