Seroprevalence of Chikungunya Virus in a rural community in Brazil

Detalhes bibliográficos
Autor(a) principal: Cunha, Rivaldo V.
Data de Publicação: 2017
Outros Autores: Trinta, Karen S., Montalbano, Camila A., Sucupira, Michel V. F., Lima, Maricelia M. de, Marques, Erenilde, Romanholi, Izilyanne H., Croda, Julio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/17793
Resumo: Universidade Federal do Mato Grosso do Sul. Faculdade de Medicina. Campo Grande, MS, Brasil / 2 Fundação Oswaldo Cruz Mato Grosso do Sul. Campo Grande, MS, Brasil.
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spelling Cunha, Rivaldo V.Trinta, Karen S.Montalbano, Camila A.Sucupira, Michel V. F.Lima, Maricelia M. deMarques, ErenildeRomanholi, Izilyanne H.Croda, Julio2017-02-13T11:34:39Z2017-02-13T11:34:39Z2017CUNHA, Rivaldo V. et al. Seroprevalence of Chikungunya Virus in a Rural Community in Brazil. PLOS Neglected Tropical Diseases, San Francisco, CA, p. 1-11, Jan. 20, 2017.1935-2735https://www.arca.fiocruz.br/handle/icict/1779310.1371/journal.pntd.0005319engPLOS Blogs NetworkVírus Chikungunya (CHIKV)EpidemiaFebre de ChikungunyaCHIKVChikungunya virus (CHIKV)EpidemicChikungunya FeverCHIKVVírus ChikungunyaFebre de ChikungunyaEpidemiasSeroprevalence of Chikungunya Virus in a rural community in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Mato Grosso do Sul. Faculdade de Medicina. Campo Grande, MS, Brasil / 2 Fundação Oswaldo Cruz Mato Grosso do Sul. Campo Grande, MS, Brasil.Fundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, Brasil.Universidade Federal do Mato Grosso do Sul. Faculdade de Medicina. Campo Grande, MS, Brasil.Fundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, Brasil.Departamento Municipal de Saúde de Feira de Santana. Feira de Santana, BA, Brasil / Universidade de Feira de Santana, Feira de Santana, BA, Brasil.Universidade de Feira de Santana, Feira de Santana, BA, Brasil.Universidade Federal do Mato Grosso do Sul. Faculdade de Medicina. Campo Grande, MS, Brasil.Fundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, Brasil / Universidade Federal do Mato Grosso do Sul. Faculdade de Ciências da Saúde. Campo Grande, MS, BrasilBackground: The emergence of the Chikungunya virus (CHIKV) is currently expanding. In 2015, 38,332 cases of Chikungunya were reported to the Brazilian epidemiological surveillance system. Eighteen months after notification of the first case in the city of Feira de Santana, we conducted the first serosurvey to define the magnitude of transmission in a rural community in Brazil. Methodology/Main findings: The serosurvey was conducted in a random sample of 450 residences in the Chapada district, located 100 kilometers from Feira de Santana. We administered questionnaires and tested 120 sera from Chapada district residents for CHIKV IgM- and IgG-specific antibodies. An individual with CHIKV infection was defined as any person with CHIKV IgM or IgG antibodies detected in the serum. One Hundred cases of Chikungunya were reported after prolonged rainfall, which reinforced the relationship between the rainfall index and CHIKV transmission. Eighteen months after the start of the outbreak, we identified a seroprevalence of 20% (95% CI, 15.4±35%). CHIKV IgG- and IgM-specific antibodies were detected in 22/120 (18.3%) and 6/120 (5.0%) individuals, respectively. Among seropositive patients, 13/24 (54.2%) reported fever and joint pain over the previous two years (p<0.01). The rate of symptomatic CHIKV infection was 40.7%. Conclusions/Significance: We identified a moderate seroprevalence of Chikungunya in the Chapada district, and in half of the confirmed CHIKV infections, patients reported arthralgia and fever over the previous two years.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/17793/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALSeroprevalence of Chikungunya Virus in a Rural Community in Brazil.pdfSeroprevalence of Chikungunya Virus in a Rural Community in Brazil.pdfapplication/pdf669769https://www.arca.fiocruz.br/bitstream/icict/17793/2/Seroprevalence%20of%20Chikungunya%20Virus%20in%20a%20Rural%20Community%20in%20Brazil.pdfb819035da8ba6d8c6afb63fc773bb492MD52TEXTSeroprevalence of Chikungunya Virus in a Rural Community in Brazil.pdf.txtSeroprevalence of Chikungunya Virus in a Rural Community 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dc.title.pt_BR.fl_str_mv Seroprevalence of Chikungunya Virus in a rural community in Brazil
title Seroprevalence of Chikungunya Virus in a rural community in Brazil
spellingShingle Seroprevalence of Chikungunya Virus in a rural community in Brazil
Cunha, Rivaldo V.
Vírus Chikungunya (CHIKV)
Epidemia
Febre de Chikungunya
CHIKV
Chikungunya virus (CHIKV)
Epidemic
Chikungunya Fever
CHIKV
Vírus Chikungunya
Febre de Chikungunya
Epidemias
title_short Seroprevalence of Chikungunya Virus in a rural community in Brazil
title_full Seroprevalence of Chikungunya Virus in a rural community in Brazil
title_fullStr Seroprevalence of Chikungunya Virus in a rural community in Brazil
title_full_unstemmed Seroprevalence of Chikungunya Virus in a rural community in Brazil
title_sort Seroprevalence of Chikungunya Virus in a rural community in Brazil
author Cunha, Rivaldo V.
author_facet Cunha, Rivaldo V.
Trinta, Karen S.
Montalbano, Camila A.
Sucupira, Michel V. F.
Lima, Maricelia M. de
Marques, Erenilde
Romanholi, Izilyanne H.
Croda, Julio
author_role author
author2 Trinta, Karen S.
Montalbano, Camila A.
Sucupira, Michel V. F.
Lima, Maricelia M. de
Marques, Erenilde
Romanholi, Izilyanne H.
Croda, Julio
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cunha, Rivaldo V.
Trinta, Karen S.
Montalbano, Camila A.
Sucupira, Michel V. F.
Lima, Maricelia M. de
Marques, Erenilde
Romanholi, Izilyanne H.
Croda, Julio
dc.subject.other.pt_BR.fl_str_mv Vírus Chikungunya (CHIKV)
Epidemia
Febre de Chikungunya
CHIKV
topic Vírus Chikungunya (CHIKV)
Epidemia
Febre de Chikungunya
CHIKV
Chikungunya virus (CHIKV)
Epidemic
Chikungunya Fever
CHIKV
Vírus Chikungunya
Febre de Chikungunya
Epidemias
dc.subject.en.pt_BR.fl_str_mv Chikungunya virus (CHIKV)
Epidemic
Chikungunya Fever
CHIKV
dc.subject.decs.pt_BR.fl_str_mv Vírus Chikungunya
Febre de Chikungunya
Epidemias
description Universidade Federal do Mato Grosso do Sul. Faculdade de Medicina. Campo Grande, MS, Brasil / 2 Fundação Oswaldo Cruz Mato Grosso do Sul. Campo Grande, MS, Brasil.
publishDate 2017
dc.date.accessioned.fl_str_mv 2017-02-13T11:34:39Z
dc.date.available.fl_str_mv 2017-02-13T11:34:39Z
dc.date.issued.fl_str_mv 2017
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CUNHA, Rivaldo V. et al. Seroprevalence of Chikungunya Virus in a Rural Community in Brazil. PLOS Neglected Tropical Diseases, San Francisco, CA, p. 1-11, Jan. 20, 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/17793
dc.identifier.issn.pt_BR.fl_str_mv 1935-2735
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pntd.0005319
identifier_str_mv CUNHA, Rivaldo V. et al. Seroprevalence of Chikungunya Virus in a Rural Community in Brazil. PLOS Neglected Tropical Diseases, San Francisco, CA, p. 1-11, Jan. 20, 2017.
1935-2735
10.1371/journal.pntd.0005319
url https://www.arca.fiocruz.br/handle/icict/17793
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv PLOS Blogs Network
publisher.none.fl_str_mv PLOS Blogs Network
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/17793/1/license.txt
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