Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/41186 |
Resumo: | Fundação de Dermatologia Tropical e Venereologia Alfredo da Matta. Manaus, AM, Brasil. |
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Cruz, RossileneBührer-Sékula, SamiraPenna, Maria Lucia FernandesPenna, Gerson OliveiraTalhari, Sinésio2020-05-11T18:26:12Z2020-05-11T18:26:12Z2017CRUZ, Rossilene Conceição da Silva. Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 92, n. 6, p. 761-673, nov./dec. 2017.1806-4841https://www.arca.fiocruz.br/handle/icict/4118610.1590/abd1806-4841.20176724engSociedade Brasileira de DermatologiaClofazimineDapsoneDrug Therapy, CombinationLeprostatic AgentsLeprosyPatient SatisfactionRifampinTreatment OutcomeCombined modality therapyDrug combinationsLeprosyTherapeuticsClofaziminaDapsonaHansenostáticosHanseníaseSatisfação do PacienteRifampinaResultado do TratamentoLeprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patientsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação de Dermatologia Tropical e Venereologia Alfredo da Matta. Manaus, AM, Brasil.Universidade Federal do Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil.Universidade Federal Fluminense. Departamento de Epidemiologia e Bioestatística. Niterói, RJ, Brasil.Universidade de Brasília. Faculdade de Medicina. Núcleo de Medicina Tropical. Brasília, DF, Brasil / Fundação Oswaldo Cruz. Fiocruz Brasília. Brasília, DF, Brasil.Universidade Nilton Lins. Manaus, AM, Brasil / Universidade Estadual do Amazonas. Manaus, AM, Brasil.In this review, the most relevant and current epidemiological data, the main clinical, laboratory and therapeutical aspects of leprosy are presented. Detailed discussion of the main drugs used for leprosy treatment, their most relevant adverse effects, evolution of the therapeutic regimen, from dapsone as a monotherapy to the proposed polychemotherapy by World Health Organization (WHO) can be found in this CME. We specifically highlight the drug acceptability, reduction in treatment duration and the most recent proposal of a single therapeutic regimen, with a fixed six months duration, for all clinical presentations, regardless of their classification.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83074https://www.arca.fiocruz.br/bitstream/icict/41186/1/license.txtd3e717dbb24bfc607ede047f44d29a0eMD51ORIGINALve_Gerson_Penna_etal.pdfve_Gerson_Penna_etal.pdfapplication/pdf1472745https://www.arca.fiocruz.br/bitstream/icict/41186/2/ve_Gerson_Penna_etal.pdf0b7d9fcdccb4f9d730e983efe23154abMD52TEXTve_Gerson_Penna_etal.pdf.txtve_Gerson_Penna_etal.pdf.txtExtracted texttext/plain70267https://www.arca.fiocruz.br/bitstream/icict/41186/3/ve_Gerson_Penna_etal.pdf.txt4b5692d5bbb42d785cb5dde35bc4001dMD53icict/411862020-05-12 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| dc.title.pt_BR.fl_str_mv |
Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients |
| title |
Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients |
| spellingShingle |
Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients Cruz, Rossilene Clofazimine Dapsone Drug Therapy, Combination Leprostatic Agents Leprosy Patient Satisfaction Rifampin Treatment Outcome Combined modality therapy Drug combinations Leprosy Therapeutics Clofazimina Dapsona Hansenostáticos Hanseníase Satisfação do Paciente Rifampina Resultado do Tratamento |
| title_short |
Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients |
| title_full |
Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients |
| title_fullStr |
Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients |
| title_full_unstemmed |
Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients |
| title_sort |
Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients |
| author |
Cruz, Rossilene |
| author_facet |
Cruz, Rossilene Bührer-Sékula, Samira Penna, Maria Lucia Fernandes Penna, Gerson Oliveira Talhari, Sinésio |
| author_role |
author |
| author2 |
Bührer-Sékula, Samira Penna, Maria Lucia Fernandes Penna, Gerson Oliveira Talhari, Sinésio |
| author2_role |
author author author author |
| dc.contributor.author.fl_str_mv |
Cruz, Rossilene Bührer-Sékula, Samira Penna, Maria Lucia Fernandes Penna, Gerson Oliveira Talhari, Sinésio |
| dc.subject.mesh.pt_BR.fl_str_mv |
Clofazimine Dapsone Drug Therapy, Combination Leprostatic Agents Leprosy Patient Satisfaction Rifampin Treatment Outcome |
| topic |
Clofazimine Dapsone Drug Therapy, Combination Leprostatic Agents Leprosy Patient Satisfaction Rifampin Treatment Outcome Combined modality therapy Drug combinations Leprosy Therapeutics Clofazimina Dapsona Hansenostáticos Hanseníase Satisfação do Paciente Rifampina Resultado do Tratamento |
| dc.subject.en.pt_BR.fl_str_mv |
Combined modality therapy Drug combinations Leprosy Therapeutics |
| dc.subject.decs.pt_BR.fl_str_mv |
Clofazimina Dapsona Hansenostáticos Hanseníase Satisfação do Paciente Rifampina Resultado do Tratamento |
| description |
Fundação de Dermatologia Tropical e Venereologia Alfredo da Matta. Manaus, AM, Brasil. |
| publishDate |
2017 |
| dc.date.issued.fl_str_mv |
2017 |
| dc.date.accessioned.fl_str_mv |
2020-05-11T18:26:12Z |
| dc.date.available.fl_str_mv |
2020-05-11T18:26:12Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.citation.fl_str_mv |
CRUZ, Rossilene Conceição da Silva. Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 92, n. 6, p. 761-673, nov./dec. 2017. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/41186 |
| dc.identifier.issn.pt_BR.fl_str_mv |
1806-4841 |
| dc.identifier.doi.none.fl_str_mv |
10.1590/abd1806-4841.20176724 |
| identifier_str_mv |
CRUZ, Rossilene Conceição da Silva. Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 92, n. 6, p. 761-673, nov./dec. 2017. 1806-4841 10.1590/abd1806-4841.20176724 |
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https://www.arca.fiocruz.br/handle/icict/41186 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Sociedade Brasileira de Dermatologia |
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Sociedade Brasileira de Dermatologia |
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reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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