Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL)

Detalhes bibliográficos
Autor(a) principal: Costa, Af Ali Uthant Moreira Lima da
Data de Publicação: 2004
Outros Autores: Saldanha, Ana Cristina Rodrigues, Leite, Bruno M. C., Ramos, Bruno, Junior, Ibraim A., Noronha, Almério Libório Lopes de, Bafica, Andre Luiz Barbosa, Barral, Aldina Maria Prado, Corbett, Carlos Eduardo Pereira, Costa, Jackson Mauricio Lopes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: doi:10.1016/j.actatropica.2005.06.016
Texto Completo: https://www.arca.fiocruz.br/handle/icict/2820
Resumo: Federal University of Maranhão. Nucleus of Tropical Pathology and Social Medicine. São Luís, MA, Brasil.
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spelling Costa, Af Ali Uthant Moreira Lima daSaldanha, Ana Cristina RodriguesLeite, Bruno M. C.Ramos, BrunoJunior, Ibraim A.Noronha, Almério Libório Lopes deBafica, Andre Luiz BarbosaBarral, Aldina Maria PradoCorbett, Carlos Eduardo PereiraCosta, Jackson Mauricio Lopes2011-08-30T18:15:23Z2011-08-30T18:15:23Z2004COSTA, Af Ali Uthant Moreira Lima da et al. Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL). Acta Tropica, v.96, n. 1, p. 9-15, 2005.1873-6254https://www.arca.fiocruz.br/handle/icict/2820doi:10.1016/j.actatropica.2005.06.016engAdolescenteAdultoOsso e OssosFemininoHumanosLeishmaniose Tegumentar DifusaMasculinoDiffuse cutaneous LeishmaniasisBone alterationsScintigraphyImaging examsImaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFederal University of Maranhão. Nucleus of Tropical Pathology and Social Medicine. São Luís, MA, Brasil.Federal University of Maranhão. Nucleus of Tropical Pathology and Social Medicine. São Luís, MA, Brasil.Nuclear Medicine Service. Nuclear Maranhão Clinic. São Luis, MA, Brazil.Nuclear Medicine Service. Nuclear Maranhão Clinic. São Luis, MA, Brazil.Nuclear Medicine Service. Nuclear Maranhão Clinic. São Luis, MA, Brazil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brazil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brazil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brazil.University of São Paulo. Laboratory of Immunopathology (LIM-50). São Paulo, SP, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brazil.We studied bone lesion alterations in three patients with diffuse cutaneous leishmaniasis (DCL) by imaging exams (radiography and scintigraphy) and histopathology. Two patients had bone lesions of distal extremities of hands and feet, and one infiltrating plaques in the skin. The study was conducted at three specialized centers (Presidente Dutra Hospital/Nucleus of Tropical Pathology, UFMA-MA; Gonc¸alo Moniz Research Center-FIOCRUZ-BA; Laboratory of Pathology of Infectious Diseases (LIM-50), University of S˜ao Paulo, SP). Three-phase bone scintigraphy demonstrated high sensitivity and specificity for bone lesions, showing increased uptake of the radiopharmaceutical at sites of active lesions. In contrast, radiography demonstrated lytic lesions, cortical destruction and local osteopenia of the bone extremeties in two patients. Histopathological analysis showed sequestration with presence of amastigote forms of Leishmania (osteomyelitis), mononuclear cells and macrophages containing amastigote forms of Leishmania in one patient. These preliminary data indicate that imaging exams (radiography and scintigraphy) are important in the evaluation of bone lesions in diffuse cutaneous leishmaniasis and should be included in the routine histopathological diagnosis of the disease and follow-up of bone lesionsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALCosta AA Imaging exams of bone....pdfCosta AA Imaging exams of bone....pdfapplication/pdf194017https://www.arca.fiocruz.br/bitstream/icict/2820/1/Costa%20AA%20Imaging%20exams%20of%20bone....pdf362322b9ce5037335fdb810d85041da2MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/2820/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTCosta AA Imaging exams of bone....pdf.txtCosta AA Imaging exams of bone....pdf.txtExtracted texttext/plain23730https://www.arca.fiocruz.br/bitstream/icict/2820/5/Costa%20AA%20Imaging%20exams%20of%20bone....pdf.txt07cf30b1eea8a01df8fd1d2e0b58c715MD55THUMBNAILCosta AA Imaging exams of bone....pdf.jpgCosta AA Imaging exams of bone....pdf.jpgGenerated Thumbnailimage/jpeg1191https://www.arca.fiocruz.br/bitstream/icict/2820/4/Costa%20AA%20Imaging%20exams%20of%20bone....pdf.jpg1ad3066736938b58775f63d00c322135MD54icict/28202023-03-15 14:33:26.44oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:26Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL)
title Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL)
spellingShingle Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL)
Costa, Af Ali Uthant Moreira Lima da
Adolescente
Adulto
Osso e Ossos
Feminino
Humanos
Leishmaniose Tegumentar Difusa
Masculino
Diffuse cutaneous Leishmaniasis
Bone alterations
Scintigraphy
Imaging exams
title_short Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL)
title_full Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL)
title_fullStr Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL)
title_full_unstemmed Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL)
title_sort Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL)
author Costa, Af Ali Uthant Moreira Lima da
author_facet Costa, Af Ali Uthant Moreira Lima da
Saldanha, Ana Cristina Rodrigues
Leite, Bruno M. C.
Ramos, Bruno
Junior, Ibraim A.
Noronha, Almério Libório Lopes de
Bafica, Andre Luiz Barbosa
Barral, Aldina Maria Prado
Corbett, Carlos Eduardo Pereira
Costa, Jackson Mauricio Lopes
author_role author
author2 Saldanha, Ana Cristina Rodrigues
Leite, Bruno M. C.
Ramos, Bruno
Junior, Ibraim A.
Noronha, Almério Libório Lopes de
Bafica, Andre Luiz Barbosa
Barral, Aldina Maria Prado
Corbett, Carlos Eduardo Pereira
Costa, Jackson Mauricio Lopes
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Costa, Af Ali Uthant Moreira Lima da
Saldanha, Ana Cristina Rodrigues
Leite, Bruno M. C.
Ramos, Bruno
Junior, Ibraim A.
Noronha, Almério Libório Lopes de
Bafica, Andre Luiz Barbosa
Barral, Aldina Maria Prado
Corbett, Carlos Eduardo Pereira
Costa, Jackson Mauricio Lopes
dc.subject.other.pt_BR.fl_str_mv Adolescente
Adulto
Osso e Ossos
Feminino
Humanos
Leishmaniose Tegumentar Difusa
Masculino
topic Adolescente
Adulto
Osso e Ossos
Feminino
Humanos
Leishmaniose Tegumentar Difusa
Masculino
Diffuse cutaneous Leishmaniasis
Bone alterations
Scintigraphy
Imaging exams
dc.subject.en.pt_BR.fl_str_mv Diffuse cutaneous Leishmaniasis
Bone alterations
Scintigraphy
Imaging exams
description Federal University of Maranhão. Nucleus of Tropical Pathology and Social Medicine. São Luís, MA, Brasil.
publishDate 2004
dc.date.issued.fl_str_mv 2004
dc.date.accessioned.fl_str_mv 2011-08-30T18:15:23Z
dc.date.available.fl_str_mv 2011-08-30T18:15:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv COSTA, Af Ali Uthant Moreira Lima da et al. Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL). Acta Tropica, v.96, n. 1, p. 9-15, 2005.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/2820
dc.identifier.issn.none.fl_str_mv 1873-6254
dc.identifier.doi.none.fl_str_mv doi:10.1016/j.actatropica.2005.06.016
identifier_str_mv COSTA, Af Ali Uthant Moreira Lima da et al. Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL). Acta Tropica, v.96, n. 1, p. 9-15, 2005.
1873-6254
doi:10.1016/j.actatropica.2005.06.016
url https://www.arca.fiocruz.br/handle/icict/2820
dc.language.iso.fl_str_mv eng
language eng
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instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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