Risk of Zika microcephaly correlates with features of maternal antibodies
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/36325 |
Resumo: | National Institutes of Health grants 5R01AI121207, R01TW009504, and R25TW009338 to A.I. Ko; National Institutes of Health pilot awards U19AI111825 and UL1TR001866 to D.F. Robbiani; National Institutes of Health grants R01AI037526, UM1AI100663, U19AI111825, UL1TR001866, and P01AI138938 to M.C. Nussenzweig; National Institutes of Health grants R01AI124690 and U19AI057229 (Cooperative Center for Human Immunology pilot project); The Rockefeller University Development Office and anonymous donors (to C.M. Rice); Fundação de Amparo `a Pesquisa do Estado da Bahia grant PET0021/2016 (to M.G. Reis); National Institutes of Health grant R21AI129479-Supplement (to K.K.A. Van Rompay) and the National Institutes of Health Office of Research Infrastructure Programs/OD (P51OD011107 to the CNPRC); the United States Food and Drug Administration contract HHSF223201610542P (to L.L. Coffey); National Institutes of Health grants R01AI100989 and R01AI133976 (to L. Rajagopal and K.M. Adams Waldorf); and National Institutes of Health grants AI083019 and AI104002 (to M. Gale Jr.) and grant P51OD010425 to the WaNPRC (to K.M. Adams Waldorf, J. Tisoncik-Go, and M. Gale Jr.). Studies at WNPRC were supported by DHHS/PHS/National Institutes of Health grant R01Al116382-01A1 (to D.H. O’Connor), in part by the National Institutes of Health Office of Research Infrastructure Programs/OD (grant P51OD011106) awarded toWNPRC, at a facility constructed in part with support from Research Facilities Improvement Programgrants RR15459-01 and RR020141-01; and National Institutes of Health core and pilot grant P51 OD011092 and grants R21-HD091032 and R01-HD08633 (to ONPRC). P.F.C. Vasconcelos was supported by Conselho Nacional de Desenvolvimento Cientifico e Tecnológico (projects 303999/2016-0, 439971/20016-0, and 440405/2016-5) and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Zika fast-track). |
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Robbiani, Davide F.Olsen, Priscilla C.Costa, FedericoWang, QiaoOliveira, Thiago YukioNery, NivisonAromolaran, AdeoluRosário, Mateus Santana doSacramento, Gielson Almeida doCruz, Jaqueline SilvaCunha, Antonio Ricardo KhouriWunder Junior, Elsio AugustoMattos, AdrianaFreitas, Bruno de PaulaSarno, ManoelArchanjo, GracindaDaltro, DinaCarvalho, Gustavo B. S.Pimentel, KleberSiqueira, Isadora Cristina deAlmeida, João R. M. deHenriques, Daniele FreitasLima, Juliana A.Vasconcelos, Pedro F. C.Babajew, Dennis SchaeferAzzopardi, Stephanie A.Bozzacco, LeoniaGazumyan, AnnaBelfort, RubensAlcântara, Ana P.Carvalho, GustavoMoreira, LiciaAraujo, KatiaciReis, Mitermayer Galvão dosKeesler, Rebekah I.Coffey, Lark L.Tisoncik-Go, JenniferGale, MichaelRajagopal, LakshmiWaldorf, Kristina M. AdamsDudley, Dawn M.Simmons, Heather A.Mejia, AndresO'Connor, David H.Steinbach, Rosemary J.Haese, NicoleSmith, JessicaLewis, AnneColgin, LoisRoberts, VictoriaFrias, AntonioKelleher, MeredithHirsch, AlecStreblow, Daniel N.Rice, Charles M.MacDonald, Margaret R.Almeida, Antonio R. P. deVan Rompay, Koen K. A.Ko, Albert IcksangNussenzweig, Michel C.2019-10-10T13:32:42Z2019-10-10T13:32:42Z2019ROBBIANI, Davide F. et al. Risk of Zika microcephaly correlates with features of maternal antibodies. Journal of Experimental Medicine, p. 1-14, Sept. 2019.0022-1007https://www.arca.fiocruz.br/handle/icict/3632510.1084/jem.20191061National Institutes of Health grants 5R01AI121207, R01TW009504, and R25TW009338 to A.I. Ko; National Institutes of Health pilot awards U19AI111825 and UL1TR001866 to D.F. Robbiani; National Institutes of Health grants R01AI037526, UM1AI100663, U19AI111825, UL1TR001866, and P01AI138938 to M.C. Nussenzweig; National Institutes of Health grants R01AI124690 and U19AI057229 (Cooperative Center for Human Immunology pilot project); The Rockefeller University Development Office and anonymous donors (to C.M. Rice); Fundação de Amparo `a Pesquisa do Estado da Bahia grant PET0021/2016 (to M.G. Reis); National Institutes of Health grant R21AI129479-Supplement (to K.K.A. Van Rompay) and the National Institutes of Health Office of Research Infrastructure Programs/OD (P51OD011107 to the CNPRC); the United States Food and Drug Administration contract HHSF223201610542P (to L.L. Coffey); National Institutes of Health grants R01AI100989 and R01AI133976 (to L. Rajagopal and K.M. Adams Waldorf); and National Institutes of Health grants AI083019 and AI104002 (to M. Gale Jr.) and grant P51OD010425 to the WaNPRC (to K.M. Adams Waldorf, J. Tisoncik-Go, and M. Gale Jr.). Studies at WNPRC were supported by DHHS/PHS/National Institutes of Health grant R01Al116382-01A1 (to D.H. O’Connor), in part by the National Institutes of Health Office of Research Infrastructure Programs/OD (grant P51OD011106) awarded toWNPRC, at a facility constructed in part with support from Research Facilities Improvement Programgrants RR15459-01 and RR020141-01; and National Institutes of Health core and pilot grant P51 OD011092 and grants R21-HD091032 and R01-HD08633 (to ONPRC). P.F.C. Vasconcelos was supported by Conselho Nacional de Desenvolvimento Cientifico e Tecnológico (projects 303999/2016-0, 439971/20016-0, and 440405/2016-5) and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Zika fast-track).The Rockefeller University. Laboratory of Molecular Immunology. New York, NY, USA.The Rockefeller University. Laboratory of Molecular Immunology. New York, NY, USA / Universidade Federal do Rio de Janeiro. Faculdade de Farmácia. Rio de Janeiro, RJ, Brasil.Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven / Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, Brasil.Fudan University. School of Basic Medical Sciences. Shanghai Medical College. Key Laboratory of Medical Molecular Virology. Shanghai, China.The Rockefeller University. Laboratory of Molecular Immunology. New York, NY, USA.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven.Secretaria de Saúde do Estado da Bahia. Hospital Geral Roberto Santos. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven.Secretaria de Saúde do Estado da Bahia. Hospital Geral Roberto Santos. Salvador, BA, Brasil.Secretaria de Saúde do Estado da Bahia. Hospital Geral Roberto Santos. Salvador, BA, Brasil / Universidade Federal de São Paulo. São Paulo, SP, Brasil.Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, Brasil.Secretaria de Saúde do Estado da Bahia. Hospital Geral Roberto Santos. Salvador, BA, Brasil.Secretaria de Saúde do Estado da Bahia. Hospital Geral Roberto Santos. Salvador, BA, Brasil.Secretaria de Saúde do Estado da Bahia. Hospital Geral Roberto Santos. Salvador, BA, Brasil.Secretaria de Saúde do Estado da Bahia. Hospital Geral Roberto Santos. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, Brasil.Ministério da Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.The Rockefeller University. Laboratory of Molecular Immunology. New York, NY.Universidade Federal do Rio de Janeiro. Faculdade de Farmácia. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Faculdade de Farmácia. Rio de Janeiro, RJ, Brasil.The Rockefeller University. Laboratory of Molecular Immunology. New York, NY, USA.Universidade Federal de São Paulo. São Paulo, SP, Brasil.Hospital Santo Amaro. Salvador, BA, Brasil.Hospital Santo Amaro. Salvador, BA, Brasil.Hospital Santo Amaro. Salvador, BA, Brasil.Hospital Aliança. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven / Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, Brasil.University of California. California National Primate Research Center. Davis, Davis, CA, USA.University of California. School of Veterinary Medicine. Department of Pathology, Microbiology, and Immunology. Davis, Davis, CA, USA.Washington National Primate Research Center. Seattle, WA, USA / University of Washington. Center for Innate Immunity and Immune Disease. Seattle, WA, USA / University of Washington. Department of Immunology. Seattle, WA, USA.Washington National Primate Research Center. Seattle, WA / University of Washington. Center for Innate Immunity and Immune Disease. Seattle, WA, USA / University of Washington. Department of Immunology. Seattle, WA, USA / University of Washington. Department of Global Health. Seattle, WA, USA.University of Washington. Department of Global Health. Seattle, WA, USA / University of Washington. Department of Pediatrics. Seattle, WA, USA / Seattle Children’s Research Institute. Center for Global Infectious Disease Research. Seattle, WA, USA.Washington National Primate Research Center. Seattle, WA, USA / University of Washington. Center for Innate Immunity and Immune Disease. Seattle, WA, USA / University of Washington. Department of Global Health. Seattle, WA, USA / University of Washington. Department of Obstetrics and Gynecology. Seattle, WA, USA.University of Wisconsin-Madison. Department of Pathology and Laboratory Medicine. Madison, WI, USA.University of Wisconsin-Madison. Wisconsin National Primate Research Center. Madison, WI, USA.University of Wisconsin-Madison. Wisconsin National Primate Research Center. Madison, WI, USA.University of Wisconsin-Madison. Department of Pathology and Laboratory Medicine. Madison, WI, USA.Oregon National Primate Research Center. Division of Reproductive and Developmental Sciences. Beaverton, OR, USA.Oregon National Primate Research Center. Division of Pathobiology and Immunology. Beaverton, OR, USA / Oregon Health and Science University. Vaccine and Gene Therapy Institute. Portland, OR, USA.Oregon Health and Science University. Vaccine and Gene Therapy Institute. Portland, OR, USA.Oregon National Primate Research Center. Pathology Services Unit, Division of Comparative Medicine. Beaverton, OR, USA.Oregon National Primate Research Center. Division of Pathobiology and Immunology. Beaverton, OR, USA.Oregon National Primate Research Center. Division of Reproductive and Developmental Sciences. Beaverton, OR, USA.Oregon National Primate Research Center. Division of Reproductive and Developmental Sciences. Beaverton, OR, USA / Oregon Health and Science University. Department of Obstetrics and Gynecology. Portland, OR, USA.Oregon National Primate Research Center. Division of Reproductive and Developmental Sciences. Beaverton, OR, USA.Oregon National Primate Research Center. Division of Pathobiology and Immunology. Beaverton, OR, USA / Oregon Health and Science University. Vaccine and Gene Therapy Institute. Portland, OR, USA.Oregon National Primate Research Center. Division of Pathobiology and Immunology. Beaverton, OR, USA / Oregon Health and Science University. Vaccine and Gene Therapy Institute. Portland, OR, USA.Universidade Federal do Rio de Janeiro. Faculdade de Farmácia. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Faculdade de Farmácia. Rio de Janeiro, RJ, Brasil.Universidade Federal da Bahia. Faculdade de Medicina. Instituto da Saúde Coletiva. Salvador, BA, Brasil.University of California. California National Primate Research Center. Davis, Davis, CA, USA / University of California. School of Veterinary Medicine. Department of Pathology, Microbiology, and Immunology. Davis, Davis, CA, USA.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, USA.The Rockefeller University. Laboratory of Molecular Immunology. New York, NY, USA / The Rockefeller University. Howard Hughes Medical Institute. New York, NY, USA.Zika virus (ZIKV) infection during pregnancy causes congenital abnormalities, including microcephaly. However, rates vary widely, and the contributing risk factors remain unclear. We examined the serum antibody response to ZIKV and other flaviviruses in Brazilian women giving birth during the 2015-2016 outbreak. Infected pregnancies with intermediate or higher ZIKV antibody enhancement titers were at increased risk to give birth to microcephalic infants compared with those with lower titers (P < 0.0001). Similarly, analysis of ZIKV-infected pregnant macaques revealed that fetal brain damage was more frequent in mothers with higher enhancement titers. Thus, features of the maternal antibodies are associated with and may contribute to the genesis of ZIKV-associated microcephaly.engRockefeller University PressVirus zikaMicrocefaliaFatores de riscoGravidezAnomalias CongênitasZika virusMicrocephalyRisk factorsPregnancyCongenital AbnormalitiesRisk of Zika microcephaly correlates with features of maternal antibodiesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/36325/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALRobbiani F D ...Risk.pdfRobbiani F D ...Risk.pdfapplication/pdf2296966https://www.arca.fiocruz.br/bitstream/icict/36325/2/Robbiani%20F%20D%20...Risk.pdf5e47aca9208f3f35c969fd82960279f4MD52TEXTRobbiani F D ...Risk.pdf.txtRobbiani F D ...Risk.pdf.txtExtracted 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InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:34:22Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Risk of Zika microcephaly correlates with features of maternal antibodies |
title |
Risk of Zika microcephaly correlates with features of maternal antibodies |
spellingShingle |
Risk of Zika microcephaly correlates with features of maternal antibodies Robbiani, Davide F. Virus zika Microcefalia Fatores de risco Gravidez Anomalias Congênitas Zika virus Microcephaly Risk factors Pregnancy Congenital Abnormalities |
title_short |
Risk of Zika microcephaly correlates with features of maternal antibodies |
title_full |
Risk of Zika microcephaly correlates with features of maternal antibodies |
title_fullStr |
Risk of Zika microcephaly correlates with features of maternal antibodies |
title_full_unstemmed |
Risk of Zika microcephaly correlates with features of maternal antibodies |
title_sort |
Risk of Zika microcephaly correlates with features of maternal antibodies |
author |
Robbiani, Davide F. |
author_facet |
Robbiani, Davide F. Olsen, Priscilla C. Costa, Federico Wang, Qiao Oliveira, Thiago Yukio Nery, Nivison Aromolaran, Adeolu Rosário, Mateus Santana do Sacramento, Gielson Almeida do Cruz, Jaqueline Silva Cunha, Antonio Ricardo Khouri Wunder Junior, Elsio Augusto Mattos, Adriana Freitas, Bruno de Paula Sarno, Manoel Archanjo, Gracinda Daltro, Dina Carvalho, Gustavo B. S. Pimentel, Kleber Siqueira, Isadora Cristina de Almeida, João R. M. de Henriques, Daniele Freitas Lima, Juliana A. Vasconcelos, Pedro F. C. Babajew, Dennis Schaefer Azzopardi, Stephanie A. Bozzacco, Leonia Gazumyan, Anna Belfort, Rubens Alcântara, Ana P. Carvalho, Gustavo Moreira, Licia Araujo, Katiaci Reis, Mitermayer Galvão dos Keesler, Rebekah I. Coffey, Lark L. Tisoncik-Go, Jennifer Gale, Michael Rajagopal, Lakshmi Waldorf, Kristina M. Adams Dudley, Dawn M. Simmons, Heather A. Mejia, Andres O'Connor, David H. Steinbach, Rosemary J. Haese, Nicole Smith, Jessica Lewis, Anne Colgin, Lois Roberts, Victoria Frias, Antonio Kelleher, Meredith Hirsch, Alec Streblow, Daniel N. Rice, Charles M. MacDonald, Margaret R. Almeida, Antonio R. P. de Van Rompay, Koen K. A. Ko, Albert Icksang Nussenzweig, Michel C. |
author_role |
author |
author2 |
Olsen, Priscilla C. Costa, Federico Wang, Qiao Oliveira, Thiago Yukio Nery, Nivison Aromolaran, Adeolu Rosário, Mateus Santana do Sacramento, Gielson Almeida do Cruz, Jaqueline Silva Cunha, Antonio Ricardo Khouri Wunder Junior, Elsio Augusto Mattos, Adriana Freitas, Bruno de Paula Sarno, Manoel Archanjo, Gracinda Daltro, Dina Carvalho, Gustavo B. S. Pimentel, Kleber Siqueira, Isadora Cristina de Almeida, João R. M. de Henriques, Daniele Freitas Lima, Juliana A. Vasconcelos, Pedro F. C. Babajew, Dennis Schaefer Azzopardi, Stephanie A. Bozzacco, Leonia Gazumyan, Anna Belfort, Rubens Alcântara, Ana P. Carvalho, Gustavo Moreira, Licia Araujo, Katiaci Reis, Mitermayer Galvão dos Keesler, Rebekah I. Coffey, Lark L. Tisoncik-Go, Jennifer Gale, Michael Rajagopal, Lakshmi Waldorf, Kristina M. Adams Dudley, Dawn M. Simmons, Heather A. Mejia, Andres O'Connor, David H. Steinbach, Rosemary J. Haese, Nicole Smith, Jessica Lewis, Anne Colgin, Lois Roberts, Victoria Frias, Antonio Kelleher, Meredith Hirsch, Alec Streblow, Daniel N. Rice, Charles M. MacDonald, Margaret R. Almeida, Antonio R. P. de Van Rompay, Koen K. A. Ko, Albert Icksang Nussenzweig, Michel C. |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Robbiani, Davide F. Olsen, Priscilla C. Costa, Federico Wang, Qiao Oliveira, Thiago Yukio Nery, Nivison Aromolaran, Adeolu Rosário, Mateus Santana do Sacramento, Gielson Almeida do Cruz, Jaqueline Silva Cunha, Antonio Ricardo Khouri Wunder Junior, Elsio Augusto Mattos, Adriana Freitas, Bruno de Paula Sarno, Manoel Archanjo, Gracinda Daltro, Dina Carvalho, Gustavo B. S. Pimentel, Kleber Siqueira, Isadora Cristina de Almeida, João R. M. de Henriques, Daniele Freitas Lima, Juliana A. Vasconcelos, Pedro F. C. Babajew, Dennis Schaefer Azzopardi, Stephanie A. Bozzacco, Leonia Gazumyan, Anna Belfort, Rubens Alcântara, Ana P. Carvalho, Gustavo Moreira, Licia Araujo, Katiaci Reis, Mitermayer Galvão dos Keesler, Rebekah I. Coffey, Lark L. Tisoncik-Go, Jennifer Gale, Michael Rajagopal, Lakshmi Waldorf, Kristina M. Adams Dudley, Dawn M. Simmons, Heather A. Mejia, Andres O'Connor, David H. Steinbach, Rosemary J. Haese, Nicole Smith, Jessica Lewis, Anne Colgin, Lois Roberts, Victoria Frias, Antonio Kelleher, Meredith Hirsch, Alec Streblow, Daniel N. Rice, Charles M. MacDonald, Margaret R. Almeida, Antonio R. P. de Van Rompay, Koen K. A. Ko, Albert Icksang Nussenzweig, Michel C. |
dc.subject.other.pt_BR.fl_str_mv |
Virus zika Microcefalia Fatores de risco Gravidez Anomalias Congênitas |
topic |
Virus zika Microcefalia Fatores de risco Gravidez Anomalias Congênitas Zika virus Microcephaly Risk factors Pregnancy Congenital Abnormalities |
dc.subject.en.pt_BR.fl_str_mv |
Zika virus Microcephaly Risk factors Pregnancy Congenital Abnormalities |
description |
National Institutes of Health grants 5R01AI121207, R01TW009504, and R25TW009338 to A.I. Ko; National Institutes of Health pilot awards U19AI111825 and UL1TR001866 to D.F. Robbiani; National Institutes of Health grants R01AI037526, UM1AI100663, U19AI111825, UL1TR001866, and P01AI138938 to M.C. Nussenzweig; National Institutes of Health grants R01AI124690 and U19AI057229 (Cooperative Center for Human Immunology pilot project); The Rockefeller University Development Office and anonymous donors (to C.M. Rice); Fundação de Amparo `a Pesquisa do Estado da Bahia grant PET0021/2016 (to M.G. Reis); National Institutes of Health grant R21AI129479-Supplement (to K.K.A. Van Rompay) and the National Institutes of Health Office of Research Infrastructure Programs/OD (P51OD011107 to the CNPRC); the United States Food and Drug Administration contract HHSF223201610542P (to L.L. Coffey); National Institutes of Health grants R01AI100989 and R01AI133976 (to L. Rajagopal and K.M. Adams Waldorf); and National Institutes of Health grants AI083019 and AI104002 (to M. Gale Jr.) and grant P51OD010425 to the WaNPRC (to K.M. Adams Waldorf, J. Tisoncik-Go, and M. Gale Jr.). Studies at WNPRC were supported by DHHS/PHS/National Institutes of Health grant R01Al116382-01A1 (to D.H. O’Connor), in part by the National Institutes of Health Office of Research Infrastructure Programs/OD (grant P51OD011106) awarded toWNPRC, at a facility constructed in part with support from Research Facilities Improvement Programgrants RR15459-01 and RR020141-01; and National Institutes of Health core and pilot grant P51 OD011092 and grants R21-HD091032 and R01-HD08633 (to ONPRC). P.F.C. Vasconcelos was supported by Conselho Nacional de Desenvolvimento Cientifico e Tecnológico (projects 303999/2016-0, 439971/20016-0, and 440405/2016-5) and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Zika fast-track). |
publishDate |
2019 |
dc.date.accessioned.fl_str_mv |
2019-10-10T13:32:42Z |
dc.date.available.fl_str_mv |
2019-10-10T13:32:42Z |
dc.date.issued.fl_str_mv |
2019 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
ROBBIANI, Davide F. et al. Risk of Zika microcephaly correlates with features of maternal antibodies. Journal of Experimental Medicine, p. 1-14, Sept. 2019. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/36325 |
dc.identifier.issn.pt_BR.fl_str_mv |
0022-1007 |
dc.identifier.doi.none.fl_str_mv |
10.1084/jem.20191061 |
identifier_str_mv |
ROBBIANI, Davide F. et al. Risk of Zika microcephaly correlates with features of maternal antibodies. Journal of Experimental Medicine, p. 1-14, Sept. 2019. 0022-1007 10.1084/jem.20191061 |
url |
https://www.arca.fiocruz.br/handle/icict/36325 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Rockefeller University Press |
publisher.none.fl_str_mv |
Rockefeller University Press |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
collection |
Repositório Institucional da FIOCRUZ (ARCA) |
bitstream.url.fl_str_mv |
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repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
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