Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4'-di-O-methylisoscutellarein

Detalhes bibliográficos
Autor(a) principal: Teles, Yanna C. F.
Data de Publicação: 2015
Outros Autores: Ribeiro Filho, Jaime, Bozza, Patrícia T., Agra, Maria de Fátima, Siheri, Weam, Igoli, John O., Gray, Alexander I., Souza, Maria de Fátima V. de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/40928
Resumo: Acesso aberto em 23/04/2020 - https://doi.org/10.1080/14786419.2015.1081196
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spelling Teles, Yanna C. F.Ribeiro Filho, JaimeBozza, Patrícia T.Agra, Maria de FátimaSiheri, WeamIgoli, John O.Gray, Alexander I.Souza, Maria de Fátima V. de2020-04-23T13:02:10Z2020-04-23T13:02:10Z2015TELES, Yanna C. F. et al. Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4′-di-Omethylisoscutellarein. Natural Product Research, v. 30, n. 16, p. 1880-1884, 11 Sept. 2015.1478-6419https://www.arca.fiocruz.br/handle/icict/4092810.1080/14786419.2015.10811961478-6427Acesso aberto em 23/04/2020 - https://doi.org/10.1080/14786419.2015.1081196Universidade Federal da Paraíba. Centro de Ciências da Saúde. Pós-Graduação em Desenvolvimento e Inovação Tecnológica em Medicamentos. João Pessoa, PB, Brasil.Faculdade Leão Sampaio. Juazeiro do Norte, CE, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Universidade Federal da Paraíba. Centro de Biotecnologia. João Pessoa, PB, Brasil.University of Strathclyde. Strathclyde Institute of Pharmacy and Biomedical Sciences. Glasgow, UK.University of Strathclyde. Strathclyde Institute of Pharmacy and Biomedical Sciences. Glasgow, UK.University of Strathclyde. Strathclyde Institute of Pharmacy and Biomedical Sciences. Glasgow, UK.Universidade Federal da Paraíba. Centro de Ciências da Saúde. Pós-Graduação em Desenvolvimento e Inovação Tecnológica em Medicamentos. João Pessoa, PB, Brasil.This study reports the first phenolics from Wissadula genus (Malvaceae) and the anti-inflammatory activity of 7,4'-di-O-methylisoscutellarein. Using chromatographic methods, five phenolic compounds were isolated from aerial parts of Wissadula periplocifolia (L.) C. Presl. The compounds were identified as 4-hydroxybenzoic acid, 3-hydroxybenzoic acid, trans-cinnamic acid, tamgermanetin and 7,4'-di-O-methylisoscutellarein using spectroscopic methods. The flavone 7,4'-di-O-methylisoscutellarein showed anti-inflammatory activity by inhibiting neutrophils recruitment in a mice model of pleurisy and by decreasing significantly the production of cytokines IL-1β and TNF-α.engTaylor and FrancisMalvaceaeWissadula periplocifoliaAtividade anti-inflamatóriaMalvaceaeWissadula periplocifolia7,4′-di-OmethylisoscutellareinAntiinflammatory activityPhenolic constituents from Wissadula periplocifolia (L.) C. 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dc.title.en.fl_str_mv Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4'-di-O-methylisoscutellarein
title Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4'-di-O-methylisoscutellarein
spellingShingle Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4'-di-O-methylisoscutellarein
Teles, Yanna C. F.
Malvaceae
Wissadula periplocifolia
Atividade anti-inflamatória
Malvaceae
Wissadula periplocifolia
7,4′-di-Omethylisoscutellarein
Antiinflammatory activity
title_short Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4'-di-O-methylisoscutellarein
title_full Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4'-di-O-methylisoscutellarein
title_fullStr Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4'-di-O-methylisoscutellarein
title_full_unstemmed Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4'-di-O-methylisoscutellarein
title_sort Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4'-di-O-methylisoscutellarein
author Teles, Yanna C. F.
author_facet Teles, Yanna C. F.
Ribeiro Filho, Jaime
Bozza, Patrícia T.
Agra, Maria de Fátima
Siheri, Weam
Igoli, John O.
Gray, Alexander I.
Souza, Maria de Fátima V. de
author_role author
author2 Ribeiro Filho, Jaime
Bozza, Patrícia T.
Agra, Maria de Fátima
Siheri, Weam
Igoli, John O.
Gray, Alexander I.
Souza, Maria de Fátima V. de
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Teles, Yanna C. F.
Ribeiro Filho, Jaime
Bozza, Patrícia T.
Agra, Maria de Fátima
Siheri, Weam
Igoli, John O.
Gray, Alexander I.
Souza, Maria de Fátima V. de
dc.subject.other.pt_BR.fl_str_mv Malvaceae
Wissadula periplocifolia
Atividade anti-inflamatória
topic Malvaceae
Wissadula periplocifolia
Atividade anti-inflamatória
Malvaceae
Wissadula periplocifolia
7,4′-di-Omethylisoscutellarein
Antiinflammatory activity
dc.subject.en.en.fl_str_mv Malvaceae
Wissadula periplocifolia
7,4′-di-Omethylisoscutellarein
Antiinflammatory activity
description Acesso aberto em 23/04/2020 - https://doi.org/10.1080/14786419.2015.1081196
publishDate 2015
dc.date.issued.fl_str_mv 2015
dc.date.accessioned.fl_str_mv 2020-04-23T13:02:10Z
dc.date.available.fl_str_mv 2020-04-23T13:02:10Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TELES, Yanna C. F. et al. Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4′-di-Omethylisoscutellarein. Natural Product Research, v. 30, n. 16, p. 1880-1884, 11 Sept. 2015.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/40928
dc.identifier.issn.pt_BR.fl_str_mv 1478-6419
dc.identifier.doi.pt_BR.fl_str_mv 10.1080/14786419.2015.1081196
dc.identifier.eissn.pt_BR.fl_str_mv 1478-6427
identifier_str_mv TELES, Yanna C. F. et al. Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4′-di-Omethylisoscutellarein. Natural Product Research, v. 30, n. 16, p. 1880-1884, 11 Sept. 2015.
1478-6419
10.1080/14786419.2015.1081196
1478-6427
url https://www.arca.fiocruz.br/handle/icict/40928
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Taylor and Francis
publisher.none.fl_str_mv Taylor and Francis
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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