SARS‑CoV‑2 genomic surveillance in Rondônia, Brazilian Western Amazon
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/47270 |
Resumo: | Fundação Oswaldo Cruz. Porto Velho, RO, Brasil / Rondônia Central Public Health Laboratory. Porto Velho, RO, Brasil. |
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Botelho-Souza, Luan FelipoLima, Felipe Souza NogueiraRoca, Tárcio PeixotoNaveca, Felipe GomesSantos, Alcione de Oliveria dosMaia, Adriana Cristina SalvadorSilva, Cicileia Correia daMendonça, Aline Linhares Ferreira de MeloLugtenburg, Celina Aparecida BertoniAzzi, Camila Flávia GomesFontes, Juliana Loca FurtadoCavalcante, SuelenRampazzo, Rita de Cássia PontelloSantos, Caio Henrique NemethGuimarães, Alice Paula Di SabatinoMáximo, Fernando RodriguesSalcedo, Juan Miguel VillalobosVieira, Deusilene Souza2021-05-20T14:07:54Z2021-05-20T14:07:54Z2021BOTELHO-SOUZA, Luan Felipo et al. SARS-CoV-2 genomic surveillance in Rondônia, Brazilian Western Amazon. Scientific Reports, v. 11, p. 1-12, 2021.2045-2322https://www.arca.fiocruz.br/handle/icict/4727010.1038/s41598-021-83203-2engScientific ReportsSARS‑CoV‑2 genomic surveillance in Rondônia, Brazilian Western Amazoninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Porto Velho, RO, Brasil / Rondônia Central Public Health Laboratory. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Porto Velho, RO, Brasil / Federal University of Rondônia. Postgraduate Program in Experimental Biology. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Porto Velho, RO, Brasil / Federal University of Rondônia. Postgraduate Program in Experimental Biology. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Leônidas and Maria Deane Institute. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Porto Velho, RO, Brasil / Rondônia Central Public Health Laboratory. Porto Velho, RO, Brasil.Rondônia State Government. State Health Secretariat. Porto Velho, RO, Brasil.Rondônia State Government. State Health Secretariat. Porto Velho, RO, Brasil.Rondônia State Government. State Health Secretariat. Porto Velho, RO, Brasil.Rondônia Central Public Health Laboratory. Porto Velho, RO, Brasil / Rondônia State Government, State Health Secretariat. Porto Velho, RO, Brasil.Rondônia State Government. State Health Secretariat. Porto Velho, RO, Brasil.Rondônia Central Public Health Laboratory. Porto Velho, RO, Brasil / Rondônia State Government, State Health Secretariat. Porto Velho, RO, Brasil.Rondônia Central Public Health Laboratory. Porto Velho, RO, Brasil / Rondônia State Government, State Health Secretariat. Porto Velho, RO, Brasil.Institute of Molecular Biology of Paraná. Curitiba, PR, Brasil.Rondônia State Government. State Health Secretariat. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Porto Velho, RO, Brasil.Rondônia State Government. State Health Secretariat. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Porto Velho, RO, Brasil / Tropical Medicine Research Center of Rondônia. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Porto Velho, RO, Brasil / Tropical Medicine Research Center of Rondônia. Porto Velho, RO, Brasil.SARS-CoV-2 has spread rapidly around the world, with Brazil currently considered an epicenter of the pandemic. The Northern region has the second highest incidence coefficient, as well as the third highest mortality rate in the country. This study aimed to investigate information about the evolutionary history of epidemic spread and genetic aspects of strains isolated on the Western Amazon, in the State of Rondônia, Brazil. It was possible to detect a total of 22 mutations. Some of these alterations may possibly be related to effects on transmissibility, the fidelity of RNA replication, the ability of cancer patients to respond to infection, beyond a mutation that emerged after the introduction of SARS-CoV-2 in Rondônia. At least two events of introduction were detected, corresponding to the B.1 and B.1.1 European lineages. An introduction was observed possibly through Argentina, where strains originated that circulated in the Minas Gerais and Ceará Brazilian states, prior to Rondônia (B.1.), as well as through the Minas Gerais state and the Federal District, which gave rise to strains that spread to Rondônia, from the capital to more rural parts of the state (B.1.1.). The findings show the need to monitor the genetic epidemiology of COVID-19, in order to surveil the virus’s evolution, dispersion and diversity.SARS-CoV-2Genomic surveillanceBrazilian Western AmazonCOVID-19info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALSARS-CoV-2 genomic surveillance in Rondônia, Brazilian Western Amazon.pdfSARS-CoV-2 genomic surveillance in Rondônia, Brazilian Western Amazon.pdfapplication/pdf4366339https://www.arca.fiocruz.br/bitstream/icict/47270/2/SARS-CoV-2%20genomic%20surveillance%20in%20Rond%c3%b4nia%2c%20Brazilian%20Western%20Amazon.pdf3c3a63a74de4121a5ee00f8e2105931eMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/47270/3/license.txt5a560609d32a3863062d77ff32785d58MD53TEXTSARS-CoV-2 genomic surveillance in Rondônia, Brazilian Western Amazon.pdf.txtSARS-CoV-2 genomic surveillance in Rondônia, Brazilian 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| dc.title.pt_BR.fl_str_mv |
SARS‑CoV‑2 genomic surveillance in Rondônia, Brazilian Western Amazon |
| title |
SARS‑CoV‑2 genomic surveillance in Rondônia, Brazilian Western Amazon |
| spellingShingle |
SARS‑CoV‑2 genomic surveillance in Rondônia, Brazilian Western Amazon Botelho-Souza, Luan Felipo SARS-CoV-2 Genomic surveillance Brazilian Western Amazon COVID-19 |
| title_short |
SARS‑CoV‑2 genomic surveillance in Rondônia, Brazilian Western Amazon |
| title_full |
SARS‑CoV‑2 genomic surveillance in Rondônia, Brazilian Western Amazon |
| title_fullStr |
SARS‑CoV‑2 genomic surveillance in Rondônia, Brazilian Western Amazon |
| title_full_unstemmed |
SARS‑CoV‑2 genomic surveillance in Rondônia, Brazilian Western Amazon |
| title_sort |
SARS‑CoV‑2 genomic surveillance in Rondônia, Brazilian Western Amazon |
| author |
Botelho-Souza, Luan Felipo |
| author_facet |
Botelho-Souza, Luan Felipo Lima, Felipe Souza Nogueira Roca, Tárcio Peixoto Naveca, Felipe Gomes Santos, Alcione de Oliveria dos Maia, Adriana Cristina Salvador Silva, Cicileia Correia da Mendonça, Aline Linhares Ferreira de Melo Lugtenburg, Celina Aparecida Bertoni Azzi, Camila Flávia Gomes Fontes, Juliana Loca Furtado Cavalcante, Suelen Rampazzo, Rita de Cássia Pontello Santos, Caio Henrique Nemeth Guimarães, Alice Paula Di Sabatino Máximo, Fernando Rodrigues Salcedo, Juan Miguel Villalobos Vieira, Deusilene Souza |
| author_role |
author |
| author2 |
Lima, Felipe Souza Nogueira Roca, Tárcio Peixoto Naveca, Felipe Gomes Santos, Alcione de Oliveria dos Maia, Adriana Cristina Salvador Silva, Cicileia Correia da Mendonça, Aline Linhares Ferreira de Melo Lugtenburg, Celina Aparecida Bertoni Azzi, Camila Flávia Gomes Fontes, Juliana Loca Furtado Cavalcante, Suelen Rampazzo, Rita de Cássia Pontello Santos, Caio Henrique Nemeth Guimarães, Alice Paula Di Sabatino Máximo, Fernando Rodrigues Salcedo, Juan Miguel Villalobos Vieira, Deusilene Souza |
| author2_role |
author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Botelho-Souza, Luan Felipo Lima, Felipe Souza Nogueira Roca, Tárcio Peixoto Naveca, Felipe Gomes Santos, Alcione de Oliveria dos Maia, Adriana Cristina Salvador Silva, Cicileia Correia da Mendonça, Aline Linhares Ferreira de Melo Lugtenburg, Celina Aparecida Bertoni Azzi, Camila Flávia Gomes Fontes, Juliana Loca Furtado Cavalcante, Suelen Rampazzo, Rita de Cássia Pontello Santos, Caio Henrique Nemeth Guimarães, Alice Paula Di Sabatino Máximo, Fernando Rodrigues Salcedo, Juan Miguel Villalobos Vieira, Deusilene Souza |
| dc.subject.en.pt_BR.fl_str_mv |
SARS-CoV-2 Genomic surveillance Brazilian Western Amazon COVID-19 |
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SARS-CoV-2 Genomic surveillance Brazilian Western Amazon COVID-19 |
| description |
Fundação Oswaldo Cruz. Porto Velho, RO, Brasil / Rondônia Central Public Health Laboratory. Porto Velho, RO, Brasil. |
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2021 |
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2021-05-20T14:07:54Z |
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2021-05-20T14:07:54Z |
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2021 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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BOTELHO-SOUZA, Luan Felipo et al. SARS-CoV-2 genomic surveillance in Rondônia, Brazilian Western Amazon. Scientific Reports, v. 11, p. 1-12, 2021. |
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https://www.arca.fiocruz.br/handle/icict/47270 |
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2045-2322 |
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10.1038/s41598-021-83203-2 |
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BOTELHO-SOUZA, Luan Felipo et al. SARS-CoV-2 genomic surveillance in Rondônia, Brazilian Western Amazon. Scientific Reports, v. 11, p. 1-12, 2021. 2045-2322 10.1038/s41598-021-83203-2 |
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