Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects

Detalhes bibliográficos
Autor(a) principal: Lima, Lyana Rodrigues Pinto
Data de Publicação: 2018
Outros Autores: Araújo, Nathália Alves de, Guterres, Alexandro, Pilotto, José Henrique, Niel, Christian, Paula, Vanessa Salete de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/30558
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ. Brasil.
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spelling Lima, Lyana Rodrigues PintoAraújo, Nathália Alves deGuterres, AlexandroPilotto, José HenriqueNiel, ChristianPaula, Vanessa Salete de2018-12-13T10:15:27Z2018-12-13T10:15:27Z2018LIMA, Lyana Rodrigues Pinto; et al. Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects. Mem Inst Oswaldo Cruz, v..113, n.12, e180328, 4p, 2018.0074-0276https://www.arca.fiocruz.br/handle/icict/305581678-8060engFundação Oswaldo Cruz. Instituto Oswaldo CruzBrasilCo-infecçãoglycoprotein BHSV-2HIVBrazilcladeCo-infectionglycoprotein BHSV-2HIVNovel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjectsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ. Brasil / Hospital Geral de Nova Iguaçu. Nova Iguaçu, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ. Brasil.BACKGROUND Human herpesvirus 2 (HHV-2) have DNA genome with a limited genetic variability and have been classified into two clades. OBJECTIVES To identify and characterise six HHV-2 isolates derived from Brazilian women. METHODS HHV-2 isolates were performed polymerase chain reaction (PCR) and sequencing of 2250 pb of the glycoprotein B (gB) coding regions. FINDINGS Four HHV-2 isolates were classified into clade B, while the remaining two, derived from HIV-1 co-infected women, showed a notable genetic divergence (> 1%). MAIN CONCLUSION The results reveal novel HHV-2 variants. The impact of these novel variants on HHV-2 pathogenesis and HIV/HHV-2 coinfection need to be investigated..info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/30558/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALliana_lima_etal_IOC_2018.pdfliana_lima_etal_IOC_2018.pdfapplication/pdf376957https://www.arca.fiocruz.br/bitstream/icict/30558/2/liana_lima_etal_IOC_2018.pdf7991858b3b6fef1b873bb46d5c8ae95bMD52TEXTliana_lima_etal_IOC_2018.pdf.txtliana_lima_etal_IOC_2018.pdf.txtExtracted texttext/plain17549https://www.arca.fiocruz.br/bitstream/icict/30558/3/liana_lima_etal_IOC_2018.pdf.txtfd41de3da421733dcfdfd29f547a96c2MD53icict/305582018-12-14 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dc.title.pt_BR.fl_str_mv Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects
title Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects
spellingShingle Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects
Lima, Lyana Rodrigues Pinto
Brasil
Co-infecção
glycoprotein B
HSV-2
HIV
Brazil
clade
Co-infection
glycoprotein B
HSV-2
HIV
title_short Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects
title_full Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects
title_fullStr Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects
title_full_unstemmed Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects
title_sort Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects
author Lima, Lyana Rodrigues Pinto
author_facet Lima, Lyana Rodrigues Pinto
Araújo, Nathália Alves de
Guterres, Alexandro
Pilotto, José Henrique
Niel, Christian
Paula, Vanessa Salete de
author_role author
author2 Araújo, Nathália Alves de
Guterres, Alexandro
Pilotto, José Henrique
Niel, Christian
Paula, Vanessa Salete de
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Lima, Lyana Rodrigues Pinto
Araújo, Nathália Alves de
Guterres, Alexandro
Pilotto, José Henrique
Niel, Christian
Paula, Vanessa Salete de
dc.subject.other.pt_BR.fl_str_mv Brasil
Co-infecção
glycoprotein B
HSV-2
HIV
topic Brasil
Co-infecção
glycoprotein B
HSV-2
HIV
Brazil
clade
Co-infection
glycoprotein B
HSV-2
HIV
dc.subject.en.pt_BR.fl_str_mv Brazil
clade
Co-infection
glycoprotein B
HSV-2
HIV
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ. Brasil.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-12-13T10:15:27Z
dc.date.available.fl_str_mv 2018-12-13T10:15:27Z
dc.date.issued.fl_str_mv 2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LIMA, Lyana Rodrigues Pinto; et al. Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects. Mem Inst Oswaldo Cruz, v..113, n.12, e180328, 4p, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/30558
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv LIMA, Lyana Rodrigues Pinto; et al. Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects. Mem Inst Oswaldo Cruz, v..113, n.12, e180328, 4p, 2018.
0074-0276
1678-8060
url https://www.arca.fiocruz.br/handle/icict/30558
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/30558/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/30558/2/liana_lima_etal_IOC_2018.pdf
https://www.arca.fiocruz.br/bitstream/icict/30558/3/liana_lima_etal_IOC_2018.pdf.txt
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