Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics

Detalhes bibliográficos
Autor(a) principal: Orofino-Costa, Rosane
Data de Publicação: 2017
Outros Autores: Rodrigues, Anderson Messias, Macedo, Priscila Marques de, Bernardes-Engemann, Andréa Reis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/31401
Resumo: Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Dermatology Department. Rio de Janeiro, RJ, Brazil / Universidade do Estado do Rio de Janeiro. Hospital Universitário Pedro Ernesto. Medical Mycology Laboratory. Dermatology Department. Rio de Janeiro, RJ, Brazil.
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spelling Orofino-Costa, RosaneRodrigues, Anderson MessiasMacedo, Priscila Marques deBernardes-Engemann, Andréa Reis2019-02-04T14:05:33Z2019-02-04T14:05:33Z2017OROFINO-COSTA, Rosane et al. Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics. Anais Brasileiros de Dermatologia, v. 92, n. 5, p. 606-620, 2017.0365-0596https://www.arca.fiocruz.br/handle/icict/3140110.1590/abd1806-4841.2017279engSociedade Brasileira de DermatologiaSporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeuticsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Dermatology Department. Rio de Janeiro, RJ, Brazil / Universidade do Estado do Rio de Janeiro. Hospital Universitário Pedro Ernesto. Medical Mycology Laboratory. Dermatology Department. Rio de Janeiro, RJ, Brazil.Universidade Federal de São Paulo. Department of Microbiology, Immunology and Parasitology. Laboratorial of Emerging Fungal Pathogen. São Paulo, SP, Brazil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Infectious Dermatology Clinical Research Laboratory. Rio de Janeiro, RJ, Brazil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Dermatology Department. Rio de Janeiro, RJ, Brazil / Universidade do Estado do Rio de Janeiro. Hospital Universitário Pedro Ernesto. Medical Mycology Laboratory. Dermatology Department. Rio de Janeiro, RJ, Brazil.In the late 90’s there was a change in both the route of transmission and the people at risk for sporotrichosis. This zoonotic cat-man alternative transmission route elicited changes in strategies to control the epidemic. There was a progressive increase in the number of cases involving especially children and the elderly. In addition to becoming hyperendemic, uncommon clinical pictures like immunoreactive clinical presentations or severe systemic cases have emerged. New species were identified and classified through molecular tools using more virulent clinical isolates, like S. brasiliensis, compared to the environmental isolates. Likewise, different species of Sporothrix have been associated with different geographic regions. The serological and molecular techniques are used as an auxiliary tool for the diagnosis and/or for species identification, although the isolation and the identification of Sporothrix spp. in clinical specimen is still the gold standard. Currently sporotrichosis epidemics requires the knowledge of the epidemiological-molecular profile to control the disease and the specific treatment. Itraconazole, potassium iodide, terfinafine, and amphotericin B are the available drugs in Brazil to treat sporotrichosis. The drug of choice, its posology, and treatment duration vary according to the clinical presentation, the Sporothrix species, and host immune status. New treatment choices, including a vaccine, are being developed; nevertheless, more clinical trials are required to confirm its efficacy.DiagnosisEpidemiologyMolecular biologySerologySporothrixTherapeuticsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/31401/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Macedo_Priscila_etal_INI_2017.pdfve_Macedo_Priscila_etal_INI_2017.pdfapplication/pdf3556133https://www.arca.fiocruz.br/bitstream/icict/31401/2/ve_Macedo_Priscila_etal_INI_2017.pdf9cdcc2a4d0bf5bccf56d09befd5eeee8MD52TEXTve_Macedo_Priscila_etal_INI_2017.pdf.txtve_Macedo_Priscila_etal_INI_2017.pdf.txtExtracted texttext/plain85190https://www.arca.fiocruz.br/bitstream/icict/31401/3/ve_Macedo_Priscila_etal_INI_2017.pdf.txt60ece5d96c86201c269db57a39dbeb98MD53icict/314012019-02-06 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dc.title.pt_BR.fl_str_mv Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics
title Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics
spellingShingle Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics
Orofino-Costa, Rosane
Diagnosis
Epidemiology
Molecular biology
Serology
Sporothrix
Therapeutics
title_short Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics
title_full Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics
title_fullStr Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics
title_full_unstemmed Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics
title_sort Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics
author Orofino-Costa, Rosane
author_facet Orofino-Costa, Rosane
Rodrigues, Anderson Messias
Macedo, Priscila Marques de
Bernardes-Engemann, Andréa Reis
author_role author
author2 Rodrigues, Anderson Messias
Macedo, Priscila Marques de
Bernardes-Engemann, Andréa Reis
author2_role author
author
author
dc.contributor.author.fl_str_mv Orofino-Costa, Rosane
Rodrigues, Anderson Messias
Macedo, Priscila Marques de
Bernardes-Engemann, Andréa Reis
dc.subject.en.pt_BR.fl_str_mv Diagnosis
Epidemiology
Molecular biology
Serology
Sporothrix
Therapeutics
topic Diagnosis
Epidemiology
Molecular biology
Serology
Sporothrix
Therapeutics
description Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Dermatology Department. Rio de Janeiro, RJ, Brazil / Universidade do Estado do Rio de Janeiro. Hospital Universitário Pedro Ernesto. Medical Mycology Laboratory. Dermatology Department. Rio de Janeiro, RJ, Brazil.
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2019-02-04T14:05:33Z
dc.date.available.fl_str_mv 2019-02-04T14:05:33Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv OROFINO-COSTA, Rosane et al. Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics. Anais Brasileiros de Dermatologia, v. 92, n. 5, p. 606-620, 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/31401
dc.identifier.issn.pt_BR.fl_str_mv 0365-0596
dc.identifier.doi.none.fl_str_mv 10.1590/abd1806-4841.2017279
identifier_str_mv OROFINO-COSTA, Rosane et al. Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics. Anais Brasileiros de Dermatologia, v. 92, n. 5, p. 606-620, 2017.
0365-0596
10.1590/abd1806-4841.2017279
url https://www.arca.fiocruz.br/handle/icict/31401
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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