The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature

Detalhes bibliográficos
Autor(a) principal: Machado, Bruna Aparecida Souza
Data de Publicação: 2021
Outros Autores: Hodel, Katharine Valéria Saraiva, Barbosa Júnior, Valdir Gomes, Soares, Milena Botelho Pereira, Badaró, Roberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/46251
Resumo: University Center SENAI/CIMATEC. SENAI Institute of Innovation in Health Advanced Systems. Salvador, BA, Brazil.
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spelling Machado, Bruna Aparecida SouzaHodel, Katharine Valéria SaraivaBarbosa Júnior, Valdir GomesSoares, Milena Botelho PereiraBadaró, Roberto2021-03-04T11:07:27Z2021-03-04T11:07:27Z2021MACHADO, Bruna Aparecida Souza et al. The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature. Viruses, v. 13, p. 1-36, 2021.1999-4915https://www.arca.fiocruz.br/handle/icict/4625110.3390/v13010040engMDPISARS-CoV-2COVID-19DiagnósticoTeste diagnósticos de rotinaTeste sorologicosPandemiasSARS-CoV-2COVID-19DiagnosticMolecular testingSerology testingThe Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literatureinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversity Center SENAI/CIMATEC. SENAI Institute of Innovation in Health Advanced Systems. Salvador, BA, Brazil.University Center SENAI/CIMATEC. SENAI Institute of Innovation in Health Advanced Systems. Salvador, BA, Brazil.University Center SENAI/CIMATEC. SENAI Institute of Innovation in Health Advanced Systems. Salvador, BA, Brazil.University Center SENAI/CIMATEC. SENAI Institute of Innovation in Health Advanced Systems. Salvador, BA, Brazil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.University Center SENAI/CIMATEC. SENAI Institute of Innovation in Health Advanced Systems. Salvador, BA, Brazil.Diagnostic tests have been considered as the main alternative for the control of coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as a correct diagnosis allows for decision making when facing the disease, particularly as there is a lack of effective therapeutic protocols and vaccines. Thus, in this review, we summarized the main diagnostic approaches currently available for the diagnosis of SARS-CoV-2 infection in humans based on studies available in article databases. The tests can be organized into two main categories: nucleic acid-based tests, recommended for the initial detection of the virus, and serological tests, recommended for assessing the disease progression. The studies have shown that the performance of diagnostic methods depends on different factors, such as the type of samples and the characteristics of each assay. It was identified that the positivity of the tests is mainly related to the onset of symptoms. We also observed that point-of-care diagnoses are considered as one of the main trends in this area, due to the low-cost and simplicity of the assay; however, the analytical performance must be critically analyzed. Thus, the COVID-19 pandemic has highlighted the critical role of diagnostic technologies in the control of infectious diseases.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/46251/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALMachado, Bruna Aparecida The main....pdfMachado, Bruna Aparecida The main....pdfapplication/pdf1891172https://www.arca.fiocruz.br/bitstream/icict/46251/2/Machado%2c%20Bruna%20Aparecida%20The%20main....pdf9a4cfb00c8e8a590ef069283d730f25aMD52TEXTMachado, Bruna Aparecida The main....pdf.txtMachado, Bruna Aparecida The main....pdf.txtExtracted texttext/plain146349https://www.arca.fiocruz.br/bitstream/icict/46251/3/Machado%2c%20Bruna%20Aparecida%20The%20main....pdf.txtf6d1b59f0b5f64741467725167baf03bMD53icict/462512023-03-15 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dc.title.pt_BR.fl_str_mv The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature
title The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature
spellingShingle The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature
Machado, Bruna Aparecida Souza
SARS-CoV-2
COVID-19
Diagnóstico
Teste diagnósticos de rotina
Teste sorologicos
Pandemias
SARS-CoV-2
COVID-19
Diagnostic
Molecular testing
Serology testing
title_short The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature
title_full The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature
title_fullStr The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature
title_full_unstemmed The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature
title_sort The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature
author Machado, Bruna Aparecida Souza
author_facet Machado, Bruna Aparecida Souza
Hodel, Katharine Valéria Saraiva
Barbosa Júnior, Valdir Gomes
Soares, Milena Botelho Pereira
Badaró, Roberto
author_role author
author2 Hodel, Katharine Valéria Saraiva
Barbosa Júnior, Valdir Gomes
Soares, Milena Botelho Pereira
Badaró, Roberto
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Machado, Bruna Aparecida Souza
Hodel, Katharine Valéria Saraiva
Barbosa Júnior, Valdir Gomes
Soares, Milena Botelho Pereira
Badaró, Roberto
dc.subject.other.pt_BR.fl_str_mv SARS-CoV-2
COVID-19
Diagnóstico
Teste diagnósticos de rotina
Teste sorologicos
Pandemias
topic SARS-CoV-2
COVID-19
Diagnóstico
Teste diagnósticos de rotina
Teste sorologicos
Pandemias
SARS-CoV-2
COVID-19
Diagnostic
Molecular testing
Serology testing
dc.subject.en.pt_BR.fl_str_mv SARS-CoV-2
COVID-19
Diagnostic
Molecular testing
Serology testing
description University Center SENAI/CIMATEC. SENAI Institute of Innovation in Health Advanced Systems. Salvador, BA, Brazil.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-03-04T11:07:27Z
dc.date.available.fl_str_mv 2021-03-04T11:07:27Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MACHADO, Bruna Aparecida Souza et al. The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature. Viruses, v. 13, p. 1-36, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/46251
dc.identifier.issn.pt_BR.fl_str_mv 1999-4915
dc.identifier.doi.none.fl_str_mv 10.3390/v13010040
identifier_str_mv MACHADO, Bruna Aparecida Souza et al. The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the Literature. Viruses, v. 13, p. 1-36, 2021.
1999-4915
10.3390/v13010040
url https://www.arca.fiocruz.br/handle/icict/46251
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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