A systematic scoping review of the genetic ancestry of the Brazilian population
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/39905 |
Resumo: | Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil. |
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Souza, Aracele Maria deResende, Sarah StelaSousa, Taís Nóbrega deBrito, Cristiana Ferreira Alves de2020-02-12T13:33:54Z2020-02-12T13:33:54Z2019SOUZA, Aracele Maria de et al. A systematic scoping review of the genetic ancestry of the Brazilian population. Genetics and Molecular Biology, v. 42, n. 3, p. 495-508, 2019.1415-4757https://www.arca.fiocruz.br/handle/icict/3990510.1590/1678-4685-gmb-2018-0076engSociedade Brasileira de GenéticaA systematic scoping review of the genetic ancestry of the Brazilian populationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil.The genetic background of the Brazilian population is mainly characterized by three parental populations: European, African, and Native American. The aim of this study was to overview the genetic ancestry estimates for different Brazilian geographic regions and analyze factors involved in these estimates. In this systematic scoping review were included 51 studies, comprehending 81 populations of 19 states from five regions of Brazil. To reduce the potential of bias from studies with different sampling methods, we calculated the mean genetic ancestry weighted by the number of individuals. The weighted mean proportions of European, African, and Native American ancestries were 68.1%, 19.6%, and 11.6%, respectively. At the regional level, the highest European contribution occurred in the South, while the highest African and Native American contributions occurred in the Northeastern and Northern regions, respectively. Among states in the Northeast region, Bahia and Ceará showed significant differences, suggesting distinct demographic histories. This review contributes for a broader understanding of the Brazilian ancestry and indicates that the ancestry estimates are influenced by the type of molecular marker and the sampling method.Scoping reviewGenetic ancestryBrazilian populationGenetic admixtureinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/39905/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALA systematic scoping review of the genetic.pdfA systematic scoping review of the genetic.pdfapplication/pdf12644817https://www.arca.fiocruz.br/bitstream/icict/39905/2/A%20systematic%20scoping%20review%20of%20the%20genetic.pdf39272b0b3797b55757bb0517c3dd2facMD52TEXTA systematic scoping review of the genetic.pdf.txtA systematic scoping review of the genetic.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv |
A systematic scoping review of the genetic ancestry of the Brazilian population |
title |
A systematic scoping review of the genetic ancestry of the Brazilian population |
spellingShingle |
A systematic scoping review of the genetic ancestry of the Brazilian population Souza, Aracele Maria de Scoping review Genetic ancestry Brazilian population Genetic admixture |
title_short |
A systematic scoping review of the genetic ancestry of the Brazilian population |
title_full |
A systematic scoping review of the genetic ancestry of the Brazilian population |
title_fullStr |
A systematic scoping review of the genetic ancestry of the Brazilian population |
title_full_unstemmed |
A systematic scoping review of the genetic ancestry of the Brazilian population |
title_sort |
A systematic scoping review of the genetic ancestry of the Brazilian population |
author |
Souza, Aracele Maria de |
author_facet |
Souza, Aracele Maria de Resende, Sarah Stela Sousa, Taís Nóbrega de Brito, Cristiana Ferreira Alves de |
author_role |
author |
author2 |
Resende, Sarah Stela Sousa, Taís Nóbrega de Brito, Cristiana Ferreira Alves de |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Souza, Aracele Maria de Resende, Sarah Stela Sousa, Taís Nóbrega de Brito, Cristiana Ferreira Alves de |
dc.subject.en.pt_BR.fl_str_mv |
Scoping review Genetic ancestry Brazilian population Genetic admixture |
topic |
Scoping review Genetic ancestry Brazilian population Genetic admixture |
description |
Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil. |
publishDate |
2019 |
dc.date.issued.fl_str_mv |
2019 |
dc.date.accessioned.fl_str_mv |
2020-02-12T13:33:54Z |
dc.date.available.fl_str_mv |
2020-02-12T13:33:54Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SOUZA, Aracele Maria de et al. A systematic scoping review of the genetic ancestry of the Brazilian population. Genetics and Molecular Biology, v. 42, n. 3, p. 495-508, 2019. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/39905 |
dc.identifier.issn.pt_BR.fl_str_mv |
1415-4757 |
dc.identifier.doi.none.fl_str_mv |
10.1590/1678-4685-gmb-2018-0076 |
identifier_str_mv |
SOUZA, Aracele Maria de et al. A systematic scoping review of the genetic ancestry of the Brazilian population. Genetics and Molecular Biology, v. 42, n. 3, p. 495-508, 2019. 1415-4757 10.1590/1678-4685-gmb-2018-0076 |
url |
https://www.arca.fiocruz.br/handle/icict/39905 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Sociedade Brasileira de Genética |
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Sociedade Brasileira de Genética |
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