A systematic scoping review of the genetic ancestry of the Brazilian population

Detalhes bibliográficos
Autor(a) principal: Souza, Aracele Maria de
Data de Publicação: 2019
Outros Autores: Resende, Sarah Stela, Sousa, Taís Nóbrega de, Brito, Cristiana Ferreira Alves de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/39905
Resumo: Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil.
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spelling Souza, Aracele Maria deResende, Sarah StelaSousa, Taís Nóbrega deBrito, Cristiana Ferreira Alves de2020-02-12T13:33:54Z2020-02-12T13:33:54Z2019SOUZA, Aracele Maria de et al. A systematic scoping review of the genetic ancestry of the Brazilian population. Genetics and Molecular Biology, v. 42, n. 3, p. 495-508, 2019.1415-4757https://www.arca.fiocruz.br/handle/icict/3990510.1590/1678-4685-gmb-2018-0076engSociedade Brasileira de GenéticaA systematic scoping review of the genetic ancestry of the Brazilian populationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil.The genetic background of the Brazilian population is mainly characterized by three parental populations: European, African, and Native American. The aim of this study was to overview the genetic ancestry estimates for different Brazilian geographic regions and analyze factors involved in these estimates. In this systematic scoping review were included 51 studies, comprehending 81 populations of 19 states from five regions of Brazil. To reduce the potential of bias from studies with different sampling methods, we calculated the mean genetic ancestry weighted by the number of individuals. The weighted mean proportions of European, African, and Native American ancestries were 68.1%, 19.6%, and 11.6%, respectively. At the regional level, the highest European contribution occurred in the South, while the highest African and Native American contributions occurred in the Northeastern and Northern regions, respectively. Among states in the Northeast region, Bahia and Ceará showed significant differences, suggesting distinct demographic histories. This review contributes for a broader understanding of the Brazilian ancestry and indicates that the ancestry estimates are influenced by the type of molecular marker and the sampling method.Scoping reviewGenetic ancestryBrazilian populationGenetic admixtureinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/39905/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALA systematic scoping review of the genetic.pdfA systematic scoping review of the genetic.pdfapplication/pdf12644817https://www.arca.fiocruz.br/bitstream/icict/39905/2/A%20systematic%20scoping%20review%20of%20the%20genetic.pdf39272b0b3797b55757bb0517c3dd2facMD52TEXTA systematic scoping review of the genetic.pdf.txtA systematic scoping review of the genetic.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv A systematic scoping review of the genetic ancestry of the Brazilian population
title A systematic scoping review of the genetic ancestry of the Brazilian population
spellingShingle A systematic scoping review of the genetic ancestry of the Brazilian population
Souza, Aracele Maria de
Scoping review
Genetic ancestry
Brazilian population
Genetic admixture
title_short A systematic scoping review of the genetic ancestry of the Brazilian population
title_full A systematic scoping review of the genetic ancestry of the Brazilian population
title_fullStr A systematic scoping review of the genetic ancestry of the Brazilian population
title_full_unstemmed A systematic scoping review of the genetic ancestry of the Brazilian population
title_sort A systematic scoping review of the genetic ancestry of the Brazilian population
author Souza, Aracele Maria de
author_facet Souza, Aracele Maria de
Resende, Sarah Stela
Sousa, Taís Nóbrega de
Brito, Cristiana Ferreira Alves de
author_role author
author2 Resende, Sarah Stela
Sousa, Taís Nóbrega de
Brito, Cristiana Ferreira Alves de
author2_role author
author
author
dc.contributor.author.fl_str_mv Souza, Aracele Maria de
Resende, Sarah Stela
Sousa, Taís Nóbrega de
Brito, Cristiana Ferreira Alves de
dc.subject.en.pt_BR.fl_str_mv Scoping review
Genetic ancestry
Brazilian population
Genetic admixture
topic Scoping review
Genetic ancestry
Brazilian population
Genetic admixture
description Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa em Biologia Molecular e Imunologia da Malária. Belo Horizonte, MG, Brasil.
publishDate 2019
dc.date.issued.fl_str_mv 2019
dc.date.accessioned.fl_str_mv 2020-02-12T13:33:54Z
dc.date.available.fl_str_mv 2020-02-12T13:33:54Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv SOUZA, Aracele Maria de et al. A systematic scoping review of the genetic ancestry of the Brazilian population. Genetics and Molecular Biology, v. 42, n. 3, p. 495-508, 2019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/39905
dc.identifier.issn.pt_BR.fl_str_mv 1415-4757
dc.identifier.doi.none.fl_str_mv 10.1590/1678-4685-gmb-2018-0076
identifier_str_mv SOUZA, Aracele Maria de et al. A systematic scoping review of the genetic ancestry of the Brazilian population. Genetics and Molecular Biology, v. 42, n. 3, p. 495-508, 2019.
1415-4757
10.1590/1678-4685-gmb-2018-0076
url https://www.arca.fiocruz.br/handle/icict/39905
dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
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