Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females

Detalhes bibliográficos
Autor(a) principal: Araújo, Adriana Pereira Oliveira de
Data de Publicação: 2012
Outros Autores: Telleria, Erich Loza, Dutra, Juliana da Matta Furniel, Júlio, Rute Maria, Traub-Csekö, Yara Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/15407
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitos e Vetores. Rio de Janeiro, RJ, Brasil.
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spelling Araújo, Adriana Pereira Oliveira deTelleria, Erich LozaDutra, Juliana da Matta FurnielJúlio, Rute MariaTraub-Csekö, Yara Maria2016-08-25T17:38:16Z2016-08-25T17:38:16Z2012ARAÚJO, Adriana Pereira Oliveira de; et al. Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females. Mem. Inst. Oswaldo Cruz, v.107, n.4, p.543-545, June 2012.0074-0276https://www.arca.fiocruz.br/handle/icict/1540710.1590/S0074-027620120004000161678-8060engFundação Oswaldo CruzQuitinaseMatriz peritróficaLutzomyia longipalpisLutzomyia longipalpisPeritrophic matrixChitinaseDisruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis femalesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitos e Vetores. Rio de Janeiro, RJ, Brasil.Yale School of Public Health. New Haven, CT, USA.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Laboratório de Paleoparasitologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitos e Vetores. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitos e Vetores. Rio de Janeiro, RJ, Brasil.Lutzomyia longipalpis is the most important vector of visceral leishmaniasis in Brazil. When female sandflies feed on blood, a peritrophic matrix (PM) is formed around the blood bolus. The PM is secreted by midgut cells and composed of proteins, glycoproteins and chitin microfibrils. The PM functions as both a physical barrier against pathogens present in the food bolus and blood meal digestion regulator. Previous studies of mosquitoes and sandflies have shown that the absence of a PM, resulting from adding an exogenous chitinase to the blood meal, accelerates digestion. In the present study, we analysed biological factors associated with the presence of a PM in L. longipalpis females. Insects fed blood containing chitinase (BCC) accelerated egg-laying relative to a control group fed blood without chitinase. However, in the BCC-fed insects, the number of females that died without laying eggs was higher and the number of eggs laid per female was lower. The eggs in both groups were viable and generated adults. Based on these data, we suggest that the absence of a PM accelerates nutrient acquisition, which results in premature egg production and oviposition; however, the absence of a PM reduces the total number of eggs laid per female. Reduced fecundity in the absence of a PM may be due to inefficient nutrient conversion or the loss of the protective role of the PM.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/15407/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALadriana_araujo_etal_IOC_2012.pdfadriana_araujo_etal_IOC_2012.pdfapplication/pdf407620https://www.arca.fiocruz.br/bitstream/icict/15407/2/adriana_araujo_etal_IOC_2012.pdffc9a2b2c5634f7c4ef3860fce8715c17MD52TEXTadriana_araujo_etal_IOC_2012.pdf.txtadriana_araujo_etal_IOC_2012.pdf.txtExtracted texttext/plain15162https://www.arca.fiocruz.br/bitstream/icict/15407/3/adriana_araujo_etal_IOC_2012.pdf.txt823ba65b5d35a8a0b00c42472952507dMD53icict/154072018-04-02 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dc.title.pt_BR.fl_str_mv Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females
title Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females
spellingShingle Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females
Araújo, Adriana Pereira Oliveira de
Quitinase
Matriz peritrófica
Lutzomyia longipalpis
Lutzomyia longipalpis
Peritrophic matrix
Chitinase
title_short Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females
title_full Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females
title_fullStr Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females
title_full_unstemmed Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females
title_sort Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females
author Araújo, Adriana Pereira Oliveira de
author_facet Araújo, Adriana Pereira Oliveira de
Telleria, Erich Loza
Dutra, Juliana da Matta Furniel
Júlio, Rute Maria
Traub-Csekö, Yara Maria
author_role author
author2 Telleria, Erich Loza
Dutra, Juliana da Matta Furniel
Júlio, Rute Maria
Traub-Csekö, Yara Maria
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Araújo, Adriana Pereira Oliveira de
Telleria, Erich Loza
Dutra, Juliana da Matta Furniel
Júlio, Rute Maria
Traub-Csekö, Yara Maria
dc.subject.other.pt_BR.fl_str_mv Quitinase
Matriz peritrófica
Lutzomyia longipalpis
topic Quitinase
Matriz peritrófica
Lutzomyia longipalpis
Lutzomyia longipalpis
Peritrophic matrix
Chitinase
dc.subject.en.pt_BR.fl_str_mv Lutzomyia longipalpis
Peritrophic matrix
Chitinase
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitos e Vetores. Rio de Janeiro, RJ, Brasil.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2016-08-25T17:38:16Z
dc.date.available.fl_str_mv 2016-08-25T17:38:16Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ARAÚJO, Adriana Pereira Oliveira de; et al. Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females. Mem. Inst. Oswaldo Cruz, v.107, n.4, p.543-545, June 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/15407
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02762012000400016
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv ARAÚJO, Adriana Pereira Oliveira de; et al. Disruption of the peritrophic matrix by exogenous chitinase feeding reduces fecundity in Lutzomyia longipalpis females. Mem. Inst. Oswaldo Cruz, v.107, n.4, p.543-545, June 2012.
0074-0276
10.1590/S0074-02762012000400016
1678-8060
url https://www.arca.fiocruz.br/handle/icict/15407
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
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collection Repositório Institucional da FIOCRUZ (ARCA)
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