Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration

Detalhes bibliográficos
Autor(a) principal: Pembrey, Lucy
Data de Publicação: 2018
Outros Autores: Barreto, Maurício Lima, Douwes, Jeroen, Cooper, Philip, Henderson, John, Mpairwe, Harriet, Garcia, Cristina Ardura, Chico, Martha, Brooks, Collin, Cruz Filho, Alvaro Augusto Souza da, Elliott, Alison M., Figueiredo, Camila Alexandrina Viana de, Langan, Sinéad M., Nassanga, Beatrice, Ring, Susan, Rodrigues, Laura Cunha, Pearce, Neil
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/31451
Resumo: Asthma Phenotypes study which is funded by the European Research Council (ERC) under the European Union’s Seventh Framework Programme (FP7/2007-2013) with ERC grant agreement number 668954. S.M. Langan is supported by a Wellcome Trust senior research fellowship in clinical science (205039/Z/16/Z). The Centre for Global Chronic Conditions (formerly the Centre for Global NCDs) at the London School of Hygiene and Tropical Medicine is supported by the Wellcome Trust Institutional Strategic Support Fund (097834/Z/11/B). The Centre for Public Health Research is supported by grants from the New Zealand Health Research Council. The ALSPAC study receives core support from the UK Medical Research Council, the Wellcome Trust (grant reference: 102215/2/13/2) and the University of Bristol. Funding information for this article has been deposited with the Crossref Funder Registry.
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spelling Pembrey, LucyBarreto, Maurício LimaDouwes, JeroenCooper, PhilipHenderson, JohnMpairwe, HarrietGarcia, Cristina ArduraChico, MarthaBrooks, CollinCruz Filho, Alvaro Augusto Souza daElliott, Alison M.Figueiredo, Camila Alexandrina Viana deLangan, Sinéad M.Nassanga, BeatriceRing, SusanRodrigues, Laura CunhaPearce, Neil2019-02-06T13:22:19Z2019-02-06T13:22:19Z2018PEMBREY, Lucy et al. Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration. ERJ Open Research, v. 4, p. 1-11, 2018.2312-0541https://www.arca.fiocruz.br/handle/icict/3145110.1183/23120541.00013-2018Asthma Phenotypes study which is funded by the European Research Council (ERC) under the European Union’s Seventh Framework Programme (FP7/2007-2013) with ERC grant agreement number 668954. S.M. Langan is supported by a Wellcome Trust senior research fellowship in clinical science (205039/Z/16/Z). The Centre for Global Chronic Conditions (formerly the Centre for Global NCDs) at the London School of Hygiene and Tropical Medicine is supported by the Wellcome Trust Institutional Strategic Support Fund (097834/Z/11/B). The Centre for Public Health Research is supported by grants from the New Zealand Health Research Council. The ALSPAC study receives core support from the UK Medical Research Council, the Wellcome Trust (grant reference: 102215/2/13/2) and the University of Bristol. Funding information for this article has been deposited with the Crossref Funder Registry.London School of Hygiene and Tropical Medicine. London, United Kingdom.Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimento para a Saúde. Salvador, BA, Brasil.Massey University. Centre for Public Health Research Wellington. New Zealand.St George’s University of London. London, UK / Universidad Internacional del Ecuador. Quito, Ecuador / Fundacion Ecuatoriana Para Investigacion en Salud. Quito, Ecuador.University of Bristol. Bristol Medical School. Population Health Sciences. Bristol, UK.Uganda Virus Research Institute. Uganda Research Unit on AIDS. Medical Research Council. Entebbe, Uganda.Fundacion Ecuatoriana Para Investigacion en Salud. Quito, Ecuador.Fundacion Ecuatoriana Para Investigacion en Salud. Quito, Ecuador.Massey University. Centre for Public Health Research Wellington. New Zealand.Federal University of Bahia. The Programme for Control of Asthma and Allergic Rhinitis. Salvador, BA, Brazil / Federal University of Bahia. Institute for Health Sciences. Salvador, BA, Brazil.Uganda Virus Research Institute. Uganda Research Unit on AIDS. Medical Research Council. Entebbe, Uganda.Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.London School of Hygiene and Tropical Medicine. London, United Kingdom.Uganda Virus Research Institute. Uganda Research Unit on AIDS. Medical Research Council. Entebbe, Uganda.University of Bristol. Bristol Medical School. Population Health Sciences. Bristol, UK.London School of Hygiene and Tropical Medicine. London, United Kingdom.London School of Hygiene and Tropical Medicine. London, United Kingdom / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimento para a Saúde. Salvador, BA, Brasil.The World Asthma Phenotypes (WASP) study started in 2016 and has been conducted in five centres, in the UK, New Zealand, Brazil, Ecuador and Uganda. The objectives of this study are to combine detailed biomarker and clinical information in order to 1) better understand and characterise asthma phenotypes in high-income countries (HICs) and low and middle-income countries (LMICs), and in high and low prevalence centres; 2) compare phenotype characteristics, including clinical severity; 3) assess the risk factors for each phenotype; and 4) assess how the distribution of phenotypes differs between high prevalence and low prevalence centres. Here we present the rationale and protocol for the WASP study to enable other centres around the world to carry out similar analyses using a standardised protocol. Large collaborative and integrative studies like this are essential to further our understanding of asthma phenotypes. The findings of this study will help elucidate the aetiological mechanisms of asthma and might potentially identify new causes and guide the development of new treatments, thereby enabling better management and prevention of asthma in both HICs and LMICs.engEuropean Respiratory SocietyAsmaFenotipoBiomarcadoresFatores de riscoTratamentoPrevençãoProtocolo de pesquisaColaboraçãoAsthmaPhenotypesBiomarkersRisk factorsTreatmentPreventionProtocolsCollaborationUnderstanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaborationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/31451/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALPEMBREY, L. Understanding asthma...2018.pdfPEMBREY, L. 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dc.title.pt_BR.fl_str_mv Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration
title Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration
spellingShingle Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration
Pembrey, Lucy
Asma
Fenotipo
Biomarcadores
Fatores de risco
Tratamento
Prevenção
Protocolo de pesquisa
Colaboração
Asthma
Phenotypes
Biomarkers
Risk factors
Treatment
Prevention
Protocols
Collaboration
title_short Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration
title_full Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration
title_fullStr Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration
title_full_unstemmed Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration
title_sort Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration
author Pembrey, Lucy
author_facet Pembrey, Lucy
Barreto, Maurício Lima
Douwes, Jeroen
Cooper, Philip
Henderson, John
Mpairwe, Harriet
Garcia, Cristina Ardura
Chico, Martha
Brooks, Collin
Cruz Filho, Alvaro Augusto Souza da
Elliott, Alison M.
Figueiredo, Camila Alexandrina Viana de
Langan, Sinéad M.
Nassanga, Beatrice
Ring, Susan
Rodrigues, Laura Cunha
Pearce, Neil
author_role author
author2 Barreto, Maurício Lima
Douwes, Jeroen
Cooper, Philip
Henderson, John
Mpairwe, Harriet
Garcia, Cristina Ardura
Chico, Martha
Brooks, Collin
Cruz Filho, Alvaro Augusto Souza da
Elliott, Alison M.
Figueiredo, Camila Alexandrina Viana de
Langan, Sinéad M.
Nassanga, Beatrice
Ring, Susan
Rodrigues, Laura Cunha
Pearce, Neil
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pembrey, Lucy
Barreto, Maurício Lima
Douwes, Jeroen
Cooper, Philip
Henderson, John
Mpairwe, Harriet
Garcia, Cristina Ardura
Chico, Martha
Brooks, Collin
Cruz Filho, Alvaro Augusto Souza da
Elliott, Alison M.
Figueiredo, Camila Alexandrina Viana de
Langan, Sinéad M.
Nassanga, Beatrice
Ring, Susan
Rodrigues, Laura Cunha
Pearce, Neil
dc.subject.other.pt_BR.fl_str_mv Asma
Fenotipo
Biomarcadores
Fatores de risco
Tratamento
Prevenção
Protocolo de pesquisa
Colaboração
topic Asma
Fenotipo
Biomarcadores
Fatores de risco
Tratamento
Prevenção
Protocolo de pesquisa
Colaboração
Asthma
Phenotypes
Biomarkers
Risk factors
Treatment
Prevention
Protocols
Collaboration
dc.subject.en.pt_BR.fl_str_mv Asthma
Phenotypes
Biomarkers
Risk factors
Treatment
Prevention
Protocols
Collaboration
description Asthma Phenotypes study which is funded by the European Research Council (ERC) under the European Union’s Seventh Framework Programme (FP7/2007-2013) with ERC grant agreement number 668954. S.M. Langan is supported by a Wellcome Trust senior research fellowship in clinical science (205039/Z/16/Z). The Centre for Global Chronic Conditions (formerly the Centre for Global NCDs) at the London School of Hygiene and Tropical Medicine is supported by the Wellcome Trust Institutional Strategic Support Fund (097834/Z/11/B). The Centre for Public Health Research is supported by grants from the New Zealand Health Research Council. The ALSPAC study receives core support from the UK Medical Research Council, the Wellcome Trust (grant reference: 102215/2/13/2) and the University of Bristol. Funding information for this article has been deposited with the Crossref Funder Registry.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-02-06T13:22:19Z
dc.date.available.fl_str_mv 2019-02-06T13:22:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.citation.fl_str_mv PEMBREY, Lucy et al. Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration. ERJ Open Research, v. 4, p. 1-11, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/31451
dc.identifier.issn.pt_BR.fl_str_mv 2312-0541
dc.identifier.doi.none.fl_str_mv 10.1183/23120541.00013-2018
identifier_str_mv PEMBREY, Lucy et al. Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration. ERJ Open Research, v. 4, p. 1-11, 2018.
2312-0541
10.1183/23120541.00013-2018
url https://www.arca.fiocruz.br/handle/icict/31451
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv European Respiratory Society
publisher.none.fl_str_mv European Respiratory Society
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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