No evidence of osteoporosis in young HTLV-1-infected carriers

Detalhes bibliográficos
Autor(a) principal: Santos, Antonio Carlos Silva
Data de Publicação: 2014
Outros Autores: Boa-Sorte, Ney Cristian Amaral, Campos, Carolina Carneiro de, Gadelha, Sandra Rocha, Grassi, Maria Fernanda Rios, Matos, Marcos Almeida, Castro Filho, Bernardo Galvão
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/8452
Resumo: Bahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, Brasil
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spelling Santos, Antonio Carlos SilvaBoa-Sorte, Ney Cristian AmaralCampos, Carolina Carneiro deGadelha, Sandra RochaGrassi, Maria Fernanda RiosMatos, Marcos AlmeidaCastro Filho, Bernardo Galvão2014-09-25T19:35:17Z2014-09-25T19:35:17Z2014SANTOS, A. C. S. et al. No evidence of osteoporoses in young HTLV-1-infected carriers. Brazilian Journal of Medicine and Human Health, v. 2, n. 2, p. 59-68, 2014.2317-3386https://www.arca.fiocruz.br/handle/icict/8452engEscola Bahiana de Medicina e Saúde PúblicaNo evidence of osteoporosis in young HTLV-1-infected carriersinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, BrasilBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, BrasilBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, BrasilState University of Santa Cruz. UESC. Itabuna, Bahia, BrasilBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, BrasilBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilOsteoporosis has been reported among Human T-cell Lymphotropic Virus type 1 (HTLV-1) infected aged patients with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) diagnosis. However, the association between osteoporosis and HTLV-1 infection remains unclear. This study aimed to evaluate the presence of bone disorders in young HTLV-1 asymptomatic individuals. A cross sectional study was carried out at the HTLV Reference Center in Salvador, Brazil. Forty-seven HTLV-1 infected asymptomatic and 108 healthy subjects aged between 20 to 45 years were included. Biochemical markers of bone metabolism were measured and bone mineral density (BMD) was determined at the femoral neck and at the lumbar spine (L1 -L4). Significant low BMD (Z-score <-1 ) was found in HTLV-1 infected individuals (1.177 ± 0.103) compared to control subjects (1.225 ± 0.146). In logistics regression analysis HTLV-1 infected subjects were more likely to have low BMD (OR = 3.48; 95%CI 1.29- 9.43) adjusted for low education and body mass index (BMI). Osteoporosis (Z-score <-2) was not found among HTLV-1-infected group. In conclusion, our results found a low BMD in patients infected with HTLV-1 compared to uninfected controls. However, osteoporosis was not observed. Further studies should be conducted to evaluate the relationship between HTLV-1-infection and low BMD.HTLV-1Bone mineral densityOsteoporosisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/8452/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALSantos A C S No evidence....pdfSantos A C S No evidence....pdfapplication/pdf107798https://www.arca.fiocruz.br/bitstream/icict/8452/2/Santos%20A%20C%20S%20No%20evidence....pdfa07b04c3aa76f9c2ca440e22d5dfaef7MD52TEXTSantos A C S No evidence....pdf.txtSantos A C S No evidence....pdf.txtExtracted texttext/plain30544https://www.arca.fiocruz.br/bitstream/icict/8452/3/Santos%20A%20C%20S%20No%20evidence....pdf.txt01073a9c38d84db5b9f9ce30d15c3e7cMD53icict/84522023-03-15 14:33:24.769oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:24Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv No evidence of osteoporosis in young HTLV-1-infected carriers
title No evidence of osteoporosis in young HTLV-1-infected carriers
spellingShingle No evidence of osteoporosis in young HTLV-1-infected carriers
Santos, Antonio Carlos Silva
HTLV-1
Bone mineral density
Osteoporosis
title_short No evidence of osteoporosis in young HTLV-1-infected carriers
title_full No evidence of osteoporosis in young HTLV-1-infected carriers
title_fullStr No evidence of osteoporosis in young HTLV-1-infected carriers
title_full_unstemmed No evidence of osteoporosis in young HTLV-1-infected carriers
title_sort No evidence of osteoporosis in young HTLV-1-infected carriers
author Santos, Antonio Carlos Silva
author_facet Santos, Antonio Carlos Silva
Boa-Sorte, Ney Cristian Amaral
Campos, Carolina Carneiro de
Gadelha, Sandra Rocha
Grassi, Maria Fernanda Rios
Matos, Marcos Almeida
Castro Filho, Bernardo Galvão
author_role author
author2 Boa-Sorte, Ney Cristian Amaral
Campos, Carolina Carneiro de
Gadelha, Sandra Rocha
Grassi, Maria Fernanda Rios
Matos, Marcos Almeida
Castro Filho, Bernardo Galvão
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Santos, Antonio Carlos Silva
Boa-Sorte, Ney Cristian Amaral
Campos, Carolina Carneiro de
Gadelha, Sandra Rocha
Grassi, Maria Fernanda Rios
Matos, Marcos Almeida
Castro Filho, Bernardo Galvão
dc.subject.en.pt_BR.fl_str_mv HTLV-1
Bone mineral density
Osteoporosis
topic HTLV-1
Bone mineral density
Osteoporosis
description Bahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, Brasil
publishDate 2014
dc.date.accessioned.fl_str_mv 2014-09-25T19:35:17Z
dc.date.available.fl_str_mv 2014-09-25T19:35:17Z
dc.date.issued.fl_str_mv 2014
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SANTOS, A. C. S. et al. No evidence of osteoporoses in young HTLV-1-infected carriers. Brazilian Journal of Medicine and Human Health, v. 2, n. 2, p. 59-68, 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/8452
dc.identifier.issn.none.fl_str_mv 2317-3386
identifier_str_mv SANTOS, A. C. S. et al. No evidence of osteoporoses in young HTLV-1-infected carriers. Brazilian Journal of Medicine and Human Health, v. 2, n. 2, p. 59-68, 2014.
2317-3386
url https://www.arca.fiocruz.br/handle/icict/8452
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Escola Bahiana de Medicina e Saúde Pública
publisher.none.fl_str_mv Escola Bahiana de Medicina e Saúde Pública
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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