No evidence of osteoporosis in young HTLV-1-infected carriers
Autor(a) principal: | |
---|---|
Data de Publicação: | 2014 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/8452 |
Resumo: | Bahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, Brasil |
id |
CRUZ_6c2011c2cf1b813114cb053d6460e64a |
---|---|
oai_identifier_str |
oai:www.arca.fiocruz.br:icict/8452 |
network_acronym_str |
CRUZ |
network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
repository_id_str |
2135 |
spelling |
Santos, Antonio Carlos SilvaBoa-Sorte, Ney Cristian AmaralCampos, Carolina Carneiro deGadelha, Sandra RochaGrassi, Maria Fernanda RiosMatos, Marcos AlmeidaCastro Filho, Bernardo Galvão2014-09-25T19:35:17Z2014-09-25T19:35:17Z2014SANTOS, A. C. S. et al. No evidence of osteoporoses in young HTLV-1-infected carriers. Brazilian Journal of Medicine and Human Health, v. 2, n. 2, p. 59-68, 2014.2317-3386https://www.arca.fiocruz.br/handle/icict/8452engEscola Bahiana de Medicina e Saúde PúblicaNo evidence of osteoporosis in young HTLV-1-infected carriersinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, BrasilBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, BrasilBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, BrasilState University of Santa Cruz. UESC. Itabuna, Bahia, BrasilBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, BrasilBahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilOsteoporosis has been reported among Human T-cell Lymphotropic Virus type 1 (HTLV-1) infected aged patients with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) diagnosis. However, the association between osteoporosis and HTLV-1 infection remains unclear. This study aimed to evaluate the presence of bone disorders in young HTLV-1 asymptomatic individuals. A cross sectional study was carried out at the HTLV Reference Center in Salvador, Brazil. Forty-seven HTLV-1 infected asymptomatic and 108 healthy subjects aged between 20 to 45 years were included. Biochemical markers of bone metabolism were measured and bone mineral density (BMD) was determined at the femoral neck and at the lumbar spine (L1 -L4). Significant low BMD (Z-score <-1 ) was found in HTLV-1 infected individuals (1.177 ± 0.103) compared to control subjects (1.225 ± 0.146). In logistics regression analysis HTLV-1 infected subjects were more likely to have low BMD (OR = 3.48; 95%CI 1.29- 9.43) adjusted for low education and body mass index (BMI). Osteoporosis (Z-score <-2) was not found among HTLV-1-infected group. In conclusion, our results found a low BMD in patients infected with HTLV-1 compared to uninfected controls. However, osteoporosis was not observed. Further studies should be conducted to evaluate the relationship between HTLV-1-infection and low BMD.HTLV-1Bone mineral densityOsteoporosisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/8452/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALSantos A C S No evidence....pdfSantos A C S No evidence....pdfapplication/pdf107798https://www.arca.fiocruz.br/bitstream/icict/8452/2/Santos%20A%20C%20S%20No%20evidence....pdfa07b04c3aa76f9c2ca440e22d5dfaef7MD52TEXTSantos A C S No evidence....pdf.txtSantos A C S No evidence....pdf.txtExtracted texttext/plain30544https://www.arca.fiocruz.br/bitstream/icict/8452/3/Santos%20A%20C%20S%20No%20evidence....pdf.txt01073a9c38d84db5b9f9ce30d15c3e7cMD53icict/84522023-03-15 14:33:24.769oai:www.arca.fiocruz.br:icict/8452TElDRU7Dh0EgREUgRElTVFJJQlVJw4fDg08gTsODTy1FWENMVVNJVkEKCkFvIGNvbmNvcmRhciBlIGFjZWl0YXIgZXN0YSBsaWNlbsOnYSB2b2PDqiAoYXV0b3Igb3UgZGV0ZW50b3IgZG9zIGRpcmVpdG9zIGF1dG9yYWlzKToKCmEpIERlY2xhcmEgcXVlIGNvbmhlY2UgYSBwb2zDrXRpY2EgZGUgY29weXJpZ2h0IGRhIGVkaXRvcmEgZG8gc2V1IGRvY3VtZW50by4KCmIpIERlY2xhcmEgcXVlIGNvbmhlY2UgZSBhY2VpdGEgYXMgRGlyZXRyaXplcyBwYXJhIG8gUmVwb3NpdMOzcmlvIEluc3RpdHVjaW9uYWwgZGEgRnVuZGHDp8OjbyBPc3dhbGRvIENydXogKEZJT0NSVVopLgoKYykgQ29uY2VkZSDDoCBGSU9DUlVaIG8gZGlyZWl0byBuw6NvLWV4Y2x1c2l2byBkZSBhcnF1aXZhciwgcmVwcm9kdXppciwgY29udmVydGVyIChjb21vIGRlZmluaWRvIGEgc2VndWlyKSwgY29tdW5pY2FyCiAKZS9vdSBkaXN0cmlidWlyIG5vIFJlcG9zaXTDs3JpbyBkYSBGSU9DUlVaLCBvIGRvY3VtZW50byBlbnRyZWd1ZSAoaW5jbHVpbmRvIG8gcmVzdW1vL2Fic3RyYWN0KSBlbSBmb3JtYXRvIGRpZ2l0YWwgb3UgCgpwb3IgcXVhbHF1ZXIgb3V0cm8gbWVpby4KCmQpIERlY2xhcmEgcXVlIGF1dG9yaXphIGEgRklPQ1JVWiBhIGFycXVpdmFyIG1haXMgZGUgdW1hIGPDs3BpYSBkZXN0ZSBkb2N1bWVudG8gZSBjb252ZXJ0w6otbG8sIHNlbSBhbHRlcmFyIG8gc2V1IGNvbnRlw7pkbywgCgpwYXJhIHF1YWxxdWVyIGZvcm1hdG8gZGUgYXJxdWl2bywgbWVpbyBvdSBzdXBvcnRlLCBwYXJhIGVmZWl0b3MgZGUgc2VndXJhbsOnYSwgcHJlc2VydmHDp8OjbyAoYmFja3VwKSBlIGFjZXNzby4KCmUpIERlY2xhcmEgcXVlIG8gZG9jdW1lbnRvIHN1Ym1ldGlkbyDDqSBvIHNldSB0cmFiYWxobyBvcmlnaW5hbCwgZSBxdWUgZGV0w6ltIG8gZGlyZWl0byBkZSBjb25jZWRlciBhIHRlcmNlaXJvcyBvcyBkaXJlaXRvcyAKCmNvbnRpZG9zIG5lc3RhIGxpY2Vuw6dhLiBEZWNsYXJhIHRhbWLDqW0gcXVlIGEgZW50cmVnYSBkbyBkb2N1bWVudG8gbsOjbyBpbmZyaW5nZSBvcyBkaXJlaXRvcyBkZSBxdWFscXVlciBvdXRyYSBwZXNzb2Egb3UgZW50aWRhZGUuCgpmKSBEZWNsYXJhIHF1ZSwgbm8gY2FzbyBkbyBkb2N1bWVudG8gc3VibWV0aWRvIGNvbnRlciBtYXRlcmlhbCBkbyBxdWFsIG7Do28gZGV0w6ltIG9zIGRpcmVpdG9zIGRlIGF1dG9yLCBvYnRldmUgYSBhdXRvcml6YcOnw6NvIAoKaXJyZXN0cml0YSBkbyByZXNwZWN0aXZvIGRldGVudG9yIGRlc3NlcyBkaXJlaXRvcywgcGFyYSBjZWRlciBhIEZJT0NSVVogb3MgZGlyZWl0b3MgcmVxdWVyaWRvcyBwb3IgZXN0YSBMaWNlbsOnYSBlIGF1dG9yaXphciBhIAoKdXRpbGl6w6EtbG9zIGxlZ2FsbWVudGUuIERlY2xhcmEgdGFtYsOpbSBxdWUgZXNzZSBtYXRlcmlhbCBjdWpvcyBkaXJlaXRvcyBzw6NvIGRlIHRlcmNlaXJvcyBlc3TDoSBjbGFyYW1lbnRlIGlkZW50aWZpY2FkbyBlIHJlY29uaGVjaWRvIAoKbm8gdGV4dG8gb3UgY29udGXDumRvIGRvIGRvY3VtZW50byBlbnRyZWd1ZS4KCmcpIFNFIE8gRE9DVU1FTlRPIEVOVFJFR1VFIMOJIEJBU0VBRE8gRU0gVFJBQkFMSE8gRklOQU5DSUFETyBPVSBBUE9JQURPIFBPUiBPVVRSQSBJTlNUSVRVScOHw4NPIFFVRSBOw4NPIEEgRklPQ1JVWiwgREVDTEFSQSBRVUUgQ1VNUFJJVSAKClFVQUlTUVVFUiBPQlJJR0HDh8OVRVMgRVhJR0lEQVMgUEVMTyBSRVNQRUNUSVZPIENPTlRSQVRPIE9VIEFDT1JETy4gQSBGSU9DUlVaIGlkZW50aWZpY2Fyw6EgY2xhcmFtZW50ZSBvKHMpIG5vbWUocykgZG8ocykgYXV0b3IoZXMpIGRvcyAKCmRpcmVpdG9zIGRvIGRvY3VtZW50byBlbnRyZWd1ZSBlIG7Do28gZmFyw6EgcXVhbHF1ZXIgYWx0ZXJhw6fDo28sIHBhcmEgYWzDqW0gZG8gcHJldmlzdG8gbmEgYWzDrW5lYSBjKS4KRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:24Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
No evidence of osteoporosis in young HTLV-1-infected carriers |
title |
No evidence of osteoporosis in young HTLV-1-infected carriers |
spellingShingle |
No evidence of osteoporosis in young HTLV-1-infected carriers Santos, Antonio Carlos Silva HTLV-1 Bone mineral density Osteoporosis |
title_short |
No evidence of osteoporosis in young HTLV-1-infected carriers |
title_full |
No evidence of osteoporosis in young HTLV-1-infected carriers |
title_fullStr |
No evidence of osteoporosis in young HTLV-1-infected carriers |
title_full_unstemmed |
No evidence of osteoporosis in young HTLV-1-infected carriers |
title_sort |
No evidence of osteoporosis in young HTLV-1-infected carriers |
author |
Santos, Antonio Carlos Silva |
author_facet |
Santos, Antonio Carlos Silva Boa-Sorte, Ney Cristian Amaral Campos, Carolina Carneiro de Gadelha, Sandra Rocha Grassi, Maria Fernanda Rios Matos, Marcos Almeida Castro Filho, Bernardo Galvão |
author_role |
author |
author2 |
Boa-Sorte, Ney Cristian Amaral Campos, Carolina Carneiro de Gadelha, Sandra Rocha Grassi, Maria Fernanda Rios Matos, Marcos Almeida Castro Filho, Bernardo Galvão |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Santos, Antonio Carlos Silva Boa-Sorte, Ney Cristian Amaral Campos, Carolina Carneiro de Gadelha, Sandra Rocha Grassi, Maria Fernanda Rios Matos, Marcos Almeida Castro Filho, Bernardo Galvão |
dc.subject.en.pt_BR.fl_str_mv |
HTLV-1 Bone mineral density Osteoporosis |
topic |
HTLV-1 Bone mineral density Osteoporosis |
description |
Bahiana School of Medicine and Public Health. EBMSP. Integrative and multidisciplinary Centre of HTLV. Salvador, BA, Brasil |
publishDate |
2014 |
dc.date.accessioned.fl_str_mv |
2014-09-25T19:35:17Z |
dc.date.available.fl_str_mv |
2014-09-25T19:35:17Z |
dc.date.issued.fl_str_mv |
2014 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SANTOS, A. C. S. et al. No evidence of osteoporoses in young HTLV-1-infected carriers. Brazilian Journal of Medicine and Human Health, v. 2, n. 2, p. 59-68, 2014. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/8452 |
dc.identifier.issn.none.fl_str_mv |
2317-3386 |
identifier_str_mv |
SANTOS, A. C. S. et al. No evidence of osteoporoses in young HTLV-1-infected carriers. Brazilian Journal of Medicine and Human Health, v. 2, n. 2, p. 59-68, 2014. 2317-3386 |
url |
https://www.arca.fiocruz.br/handle/icict/8452 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Escola Bahiana de Medicina e Saúde Pública |
publisher.none.fl_str_mv |
Escola Bahiana de Medicina e Saúde Pública |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
collection |
Repositório Institucional da FIOCRUZ (ARCA) |
bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/8452/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/8452/2/Santos%20A%20C%20S%20No%20evidence....pdf https://www.arca.fiocruz.br/bitstream/icict/8452/3/Santos%20A%20C%20S%20No%20evidence....pdf.txt |
bitstream.checksum.fl_str_mv |
7d48279ffeed55da8dfe2f8e81f3b81f a07b04c3aa76f9c2ca440e22d5dfaef7 01073a9c38d84db5b9f9ce30d15c3e7c |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
_version_ |
1798324795694120960 |