A patologia da esquistossomose mansoni no coelho

Detalhes bibliográficos
Autor(a) principal: Andrade, Zilton de Araújo
Data de Publicação: 1988
Outros Autores: Ramos, Eduardo Antônio Gonçalves, Reis, Mitermayer Galvão dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/5729
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
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spelling Andrade, Zilton de AraújoRamos, Eduardo Antônio GonçalvesReis, Mitermayer Galvão dos2012-10-23T20:49:46Z2012-10-23T20:49:46Z1988ANDRADE, Z.A.; RAMOS, E.G.; Dos REIS, M.G. A patologia da esquistossomose mansoni no coelho. Memórias do Instituto Oswaldo Cruz, v. 83, n. 3, p. 323-33, jul.-sep. 1988.0074-0276https://www.arca.fiocruz.br/handle/icict/5729engA patologia da esquistossomose mansoni no coelhoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilThe pathology of schistosomiasis mansoni in rabbits was studied with special consideration to worm burden and duration of infection. Heavy and prolonged infections resulted in severe changes involving the intrahepatic portal vein branches, such as: polypoid endophlebitis, granulomatous endophlebitis and, later on, vascular occlusion and recanalization, vascular ectasia, fibrosis and hyalinization of the endothelial polyps. Living and dead adult worms, rather than the mature eggs, were the main pathogenetic factors. For some time the lesions tend to be limited to the portal vein branches, not extending to the periportal tissues, but, after 8 to 10 months, variable degree of portal, septal and intra-parenchymal fibrosis can be formed. However, both vascular and fibrotic changes in the liver had a focal distribution and therefore did not appear to cause portal hypertension and had no resemblance to the human pathology seen in cases of hepatosplenic schistosomiasis. Pathology of schistosomiasis in rabbits has peculiar aspects, which are worthwhile studying, since the model can be of interest for investigations, especially concerning the immunology and immunopathology of schistosomiasis mansoni.SchistosomiasisRabbitsPathologyVascular lesionsHepatopatias Parasitárias/patologiaEsquistossomose mansoni/patologiaAnimaisModelos Animais de DoençasFemininoFígado/ultraestruturaCirrose Hepática Experimental/patologiaMasculinoVeia Porta/ultraestruturaCoelhosinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALAndrade ZA Pathology of Schistosomiasis....pdfAndrade ZA Pathology of Schistosomiasis....pdfapplication/pdf779154https://www.arca.fiocruz.br/bitstream/icict/5729/1/Andrade%20ZA%20Pathology%20of%20Schistosomiasis....pdfd9a32612c558d975b2597ebc93580d2bMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82008https://www.arca.fiocruz.br/bitstream/icict/5729/2/license.txt06db3f0df647fd9ddff657403bbe0ee2MD52TEXTAndrade ZA Pathology of Schistosomiasis....pdf.txtAndrade ZA Pathology of Schistosomiasis....pdf.txtExtracted texttext/plain11https://www.arca.fiocruz.br/bitstream/icict/5729/5/Andrade%20ZA%20Pathology%20of%20Schistosomiasis....pdf.txtb308b7fe5c1c2bbdc0cb686d451b84aaMD55THUMBNAILAndrade ZA Pathology of Schistosomiasis....pdf.jpgAndrade ZA Pathology of Schistosomiasis....pdf.jpgGenerated Thumbnailimage/jpeg2440https://www.arca.fiocruz.br/bitstream/icict/5729/4/Andrade%20ZA%20Pathology%20of%20Schistosomiasis....pdf.jpgfc6c3c67afa04b67ad866962d1fe0234MD54icict/57292023-03-15 14:33:15.674oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:15Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv A patologia da esquistossomose mansoni no coelho
title A patologia da esquistossomose mansoni no coelho
spellingShingle A patologia da esquistossomose mansoni no coelho
Andrade, Zilton de Araújo
Schistosomiasis
Rabbits
Pathology
Vascular lesions
Hepatopatias Parasitárias/patologia
Esquistossomose mansoni/patologia
Animais
Modelos Animais de Doenças
Feminino
Fígado/ultraestrutura
Cirrose Hepática Experimental/patologia
Masculino
Veia Porta/ultraestrutura
Coelhos
title_short A patologia da esquistossomose mansoni no coelho
title_full A patologia da esquistossomose mansoni no coelho
title_fullStr A patologia da esquistossomose mansoni no coelho
title_full_unstemmed A patologia da esquistossomose mansoni no coelho
title_sort A patologia da esquistossomose mansoni no coelho
author Andrade, Zilton de Araújo
author_facet Andrade, Zilton de Araújo
Ramos, Eduardo Antônio Gonçalves
Reis, Mitermayer Galvão dos
author_role author
author2 Ramos, Eduardo Antônio Gonçalves
Reis, Mitermayer Galvão dos
author2_role author
author
dc.contributor.author.fl_str_mv Andrade, Zilton de Araújo
Ramos, Eduardo Antônio Gonçalves
Reis, Mitermayer Galvão dos
dc.subject.en.pt_BR.fl_str_mv Schistosomiasis
Rabbits
Pathology
Vascular lesions
topic Schistosomiasis
Rabbits
Pathology
Vascular lesions
Hepatopatias Parasitárias/patologia
Esquistossomose mansoni/patologia
Animais
Modelos Animais de Doenças
Feminino
Fígado/ultraestrutura
Cirrose Hepática Experimental/patologia
Masculino
Veia Porta/ultraestrutura
Coelhos
dc.subject.decs.pt_BR.fl_str_mv Hepatopatias Parasitárias/patologia
Esquistossomose mansoni/patologia
Animais
Modelos Animais de Doenças
Feminino
Fígado/ultraestrutura
Cirrose Hepática Experimental/patologia
Masculino
Veia Porta/ultraestrutura
Coelhos
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
publishDate 1988
dc.date.issued.fl_str_mv 1988
dc.date.accessioned.fl_str_mv 2012-10-23T20:49:46Z
dc.date.available.fl_str_mv 2012-10-23T20:49:46Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRADE, Z.A.; RAMOS, E.G.; Dos REIS, M.G. A patologia da esquistossomose mansoni no coelho. Memórias do Instituto Oswaldo Cruz, v. 83, n. 3, p. 323-33, jul.-sep. 1988.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/5729
dc.identifier.issn.none.fl_str_mv 0074-0276
identifier_str_mv ANDRADE, Z.A.; RAMOS, E.G.; Dos REIS, M.G. A patologia da esquistossomose mansoni no coelho. Memórias do Instituto Oswaldo Cruz, v. 83, n. 3, p. 323-33, jul.-sep. 1988.
0074-0276
url https://www.arca.fiocruz.br/handle/icict/5729
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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