Data sources for drug utilization research in Brazil - DUR-BRA study

Detalhes bibliográficos
Autor(a) principal: Leal, Lisiane Freitas
Data de Publicação: 2022
Outros Autores: Castro, Claudia Garcia Serpa Osorio de, Souza, Luiz Júpiter Carneiro de, Ferre, Felipe, Mota, Daniel Marques, Ito, Marcia, Elseviers, Monique, Lima, Elisangela da Costa, Zimmernan, Ivan Ricardo, Fulone, Izabela, Soares, Monica da Luz Carvalho, Lopes, Luciane Cruz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/60751
Resumo: O artigo está disponível em PDF, e-pub e XML.
id CRUZ_6df8379249308998329e81bf191dcb2c
oai_identifier_str oai:www.arca.fiocruz.br:icict/60751
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Leal, Lisiane FreitasCastro, Claudia Garcia Serpa Osorio deSouza, Luiz Júpiter Carneiro deFerre, FelipeMota, Daniel MarquesIto, MarciaElseviers, MoniqueLima, Elisangela da CostaZimmernan, Ivan RicardoFulone, IzabelaSoares, Monica da Luz CarvalhoLopes, Luciane Cruz2023-10-10T02:02:41Z2023-10-10T02:02:41Z2022LEAL, Lisiane Freitas et al. Data sources for drug utilization research in Brazil - DUR-BRA study. Frontiers in Pharmacology, [s. l.], v. 12, n. 789872, p. 1-13, jan. 2022.1663-9812https://www.arca.fiocruz.br/handle/icict/6075110.3389/fphar.2021.789872O artigo está disponível em PDF, e-pub e XML.This study is sponsored by the International Society of Pharmacoepidemiology ISPE/2018. LFL is supported by a postdoctoral scholarship award from the Fonds de recherche du Québec–Santé (FRQS; Quebec Foundation for Health Research) in parternership with Société québécoise d’hypertension artérielle (SQHA) — Dossier:290908 (2020–2021); and by a CIHR Drug Safety and Effectiveness Cross-Disciplinary Training Program (DSECT)— trainee funding Stream 1 (2021–2022).McGill University. Department of Epidemiology, Biostatistics and Occupational Health. Montreal, QC, Canada.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Fiocruz Brasília. Brasília, DF, Brasil.Universidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Saúde Pública. Belo Horizonte, MG, Brazil.Brazilian Health Regulatory Agency. Brasília, DF, Brazil.Centro Estadual de Educação Tecnológica Paula Souza. Professional Master’s Program in Productive Systems. São Paulo, SP, Brazil.Ghent University. Ghent, Belgium.Universidade Federal do Rio de Janeiro. Faculdade de Farmácia. Rio de Janeiro, RJ, Brazil.University of Brasília. Faculdade de Ciências da Saúde. Brasília, DF, Brazil.Brazilian Health Regulatory Agency. Brasília, DF, Brazil.University of Sorocaba. Graduate Pharmaceutical Science. Sao Paulo, SP, Brazil.Background: In Brazil, studies that map electronic healthcare databases in order to assess their suitability for use in pharmacoepidemiologic research are lacking. We aimed to identify, catalogue, and characterize Brazilian data sources for Drug Utilization Research (DUR). Methods: The present study is part of the project entitled, “Publicly Available Data Sources for Drug Utilization Research in Latin American (LatAm) Countries.” A network of Brazilian health experts was assembled to map secondary administrative data from healthcare organizations that might provide information related to medication use. A multiphase approach including internet search of institutional government websites, traditional bibliographic databases, and experts’ input was used for mapping the data sources. The reviewers searched, screened and selected the data sources independently; disagreements were resolved by consensus. Data sources were grouped into the following categories: 1) automated databases; 2) Electronic Medical Records (EMR); 3) national surveys or datasets; 4) adverse event reporting systems; and 5) others. Each data source was characterized by accessibility, geographic granularity, setting, type of data (aggregate or individual-level), and years of coverage. We also searched for publications related to each data source. Results: A total of 62 data sources were identified and screened; 38 met the eligibility criteria for inclusion and were fully characterized. We grouped 23 (60%) as automated databases, four (11%) as adverse event reporting systems, four (11%) as EMRs, three (8%) as national surveys or datasets, and four (11%) as other types. Eighteen (47%) were classified as publicly and conveniently accessible online; providing information at national level. Most of them offered more than 5 years of comprehensive data coverage, and presented data at both the individual and aggregated levels. No information about population coverage was found. Drug coding is not uniform; each data source has its own coding system, depending on the purpose of the data. At least one scientific publication was found for each publicly available data source. Conclusions: There are several types of data sources for DUR in Brazil, but a uniform system for drug classification and data quality evaluation does not exist. The extent of population covered by year is unknown. Our comprehensive and structured inventory reveals a need for full characterization of these data sources.engFrontiers Media S.A.Data sources for drug utilization research in Brazil - DUR-BRA studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlePharmacoepidemiologyHealth information systemsDatabases (all types)BrazilDatabase management systemsPharmaceutical preparationsData sourcesDrug utilisation researchFarmacoepidemiologiaSistemas de Informação em SaúdeBases de Dados de Produtos FarmacêuticosBases de Dados como AssuntoBrasilSistemas de Gerenciamento de Base de DadosPreparações FarmacêuticasFonte de InformaçãoUso de Medicamentosinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/60751/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALfphar-12-789872.pdffphar-12-789872.pdfARTIGO EM PDFapplication/pdf1130715https://www.arca.fiocruz.br/bitstream/icict/60751/2/fphar-12-789872.pdf78817660943eca2b8ce85cbf4796d2a7MD52fphar-12-04000.epubfphar-12-04000.epubARTIGO EM ePUBapplication/epub+zip2785589https://www.arca.fiocruz.br/bitstream/icict/60751/3/fphar-12-04000.epuba7ca5f60513604559e3c4e3fc04a8b1fMD53fphar-12-04000.xmlfphar-12-04000.xmlARTIGO EM XMLtext/xml139872https://www.arca.fiocruz.br/bitstream/icict/60751/4/fphar-12-04000.xml6b6a284f097b36b64842effae3c91c4fMD545792795.zip5792795.zipMATERIAL SUPLEMENTARapplication/zip359463https://www.arca.fiocruz.br/bitstream/icict/60751/5/5792795.zip75b233c58a43a90a1272fd00a7f6bc8aMD55icict/607512023-10-09 23:02:43.145oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-10-10T02:02:43Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv Data sources for drug utilization research in Brazil - DUR-BRA study
title Data sources for drug utilization research in Brazil - DUR-BRA study
spellingShingle Data sources for drug utilization research in Brazil - DUR-BRA study
Leal, Lisiane Freitas
Pharmacoepidemiology
Health information systems
Databases (all types)
Brazil
Database management systems
Pharmaceutical preparations
Data sources
Drug utilisation research
Farmacoepidemiologia
Sistemas de Informação em Saúde
Bases de Dados de Produtos Farmacêuticos
Bases de Dados como Assunto
Brasil
Sistemas de Gerenciamento de Base de Dados
Preparações Farmacêuticas
Fonte de Informação
Uso de Medicamentos
title_short Data sources for drug utilization research in Brazil - DUR-BRA study
title_full Data sources for drug utilization research in Brazil - DUR-BRA study
title_fullStr Data sources for drug utilization research in Brazil - DUR-BRA study
title_full_unstemmed Data sources for drug utilization research in Brazil - DUR-BRA study
title_sort Data sources for drug utilization research in Brazil - DUR-BRA study
author Leal, Lisiane Freitas
author_facet Leal, Lisiane Freitas
Castro, Claudia Garcia Serpa Osorio de
Souza, Luiz Júpiter Carneiro de
Ferre, Felipe
Mota, Daniel Marques
Ito, Marcia
Elseviers, Monique
Lima, Elisangela da Costa
Zimmernan, Ivan Ricardo
Fulone, Izabela
Soares, Monica da Luz Carvalho
Lopes, Luciane Cruz
author_role author
author2 Castro, Claudia Garcia Serpa Osorio de
Souza, Luiz Júpiter Carneiro de
Ferre, Felipe
Mota, Daniel Marques
Ito, Marcia
Elseviers, Monique
Lima, Elisangela da Costa
Zimmernan, Ivan Ricardo
Fulone, Izabela
Soares, Monica da Luz Carvalho
Lopes, Luciane Cruz
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Leal, Lisiane Freitas
Castro, Claudia Garcia Serpa Osorio de
Souza, Luiz Júpiter Carneiro de
Ferre, Felipe
Mota, Daniel Marques
Ito, Marcia
Elseviers, Monique
Lima, Elisangela da Costa
Zimmernan, Ivan Ricardo
Fulone, Izabela
Soares, Monica da Luz Carvalho
Lopes, Luciane Cruz
dc.subject.en.en_US.fl_str_mv Pharmacoepidemiology
Health information systems
Databases (all types)
Brazil
Database management systems
Pharmaceutical preparations
Data sources
Drug utilisation research
topic Pharmacoepidemiology
Health information systems
Databases (all types)
Brazil
Database management systems
Pharmaceutical preparations
Data sources
Drug utilisation research
Farmacoepidemiologia
Sistemas de Informação em Saúde
Bases de Dados de Produtos Farmacêuticos
Bases de Dados como Assunto
Brasil
Sistemas de Gerenciamento de Base de Dados
Preparações Farmacêuticas
Fonte de Informação
Uso de Medicamentos
dc.subject.decs.en_US.fl_str_mv Farmacoepidemiologia
Sistemas de Informação em Saúde
Bases de Dados de Produtos Farmacêuticos
Bases de Dados como Assunto
Brasil
Sistemas de Gerenciamento de Base de Dados
Preparações Farmacêuticas
Fonte de Informação
Uso de Medicamentos
description O artigo está disponível em PDF, e-pub e XML.
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2023-10-10T02:02:41Z
dc.date.available.fl_str_mv 2023-10-10T02:02:41Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LEAL, Lisiane Freitas et al. Data sources for drug utilization research in Brazil - DUR-BRA study. Frontiers in Pharmacology, [s. l.], v. 12, n. 789872, p. 1-13, jan. 2022.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/60751
dc.identifier.issn.en_US.fl_str_mv 1663-9812
dc.identifier.doi.none.fl_str_mv 10.3389/fphar.2021.789872
identifier_str_mv LEAL, Lisiane Freitas et al. Data sources for drug utilization research in Brazil - DUR-BRA study. Frontiers in Pharmacology, [s. l.], v. 12, n. 789872, p. 1-13, jan. 2022.
1663-9812
10.3389/fphar.2021.789872
url https://www.arca.fiocruz.br/handle/icict/60751
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media S.A.
publisher.none.fl_str_mv Frontiers Media S.A.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/60751/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/60751/2/fphar-12-789872.pdf
https://www.arca.fiocruz.br/bitstream/icict/60751/3/fphar-12-04000.epub
https://www.arca.fiocruz.br/bitstream/icict/60751/4/fphar-12-04000.xml
https://www.arca.fiocruz.br/bitstream/icict/60751/5/5792795.zip
bitstream.checksum.fl_str_mv 5a560609d32a3863062d77ff32785d58
78817660943eca2b8ce85cbf4796d2a7
a7ca5f60513604559e3c4e3fc04a8b1f
6b6a284f097b36b64842effae3c91c4f
75b233c58a43a90a1272fd00a7f6bc8a
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1798325096013627392

Registros relacionados