Lipid droplet levels vary heterogeneously in responseto simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains

Detalhes bibliográficos
Autor(a) principal: Zamith-Miranda, Daniel
Data de Publicação: 2016
Outros Autores: Palma, Mariana L., Matos, Gabriel S., Schiebel, Johnathon G., Maya-Monteiro, Clarissa M., Aronovich, Marcos, Bozza, Patrícia T., Bozza, Fernando A., Nimrichter, Leonardo, Montero-Lomeli, Monica, Marques Jr., Ernesto T. A., Martins, Flaviano S., Douradinha, Bruno
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/32573
Resumo: 2020-04-12
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spelling Zamith-Miranda, DanielPalma, Mariana L.Matos, Gabriel S.Schiebel, Johnathon G.Maya-Monteiro, Clarissa M.Aronovich, MarcosBozza, Patrícia T.Bozza, Fernando A.Nimrichter, LeonardoMontero-Lomeli, MonicaMarques Jr., Ernesto T. A.Martins, Flaviano S.Douradinha, Bruno2019-04-18T12:42:23Z2019-04-18T12:42:23Z2016ZAMITH-MIRANDA, Daniel et al. Lipid droplet levels vary heterogeneously in response to simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains. Journal of Functional Foods, v. 21, p. 193-200, 2016.1756-4646https://www.arca.fiocruz.br/handle/icict/3257310.1016/j.jff.2015.12.0132214-9414engElsevierLipid droplet levels vary heterogeneously in responseto simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strainsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-04-12Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo Goés. Laboratório de Glicobiologia de Eucariotos. Rio de Janeiro, RJ, Brasil.Universidade de São Paulo. Faculdade de Medicina. Laboratório de Dermatologia e Imunodeficiências. São Paulo, SP, Brasil / University of Pittsburgh. Center for Vaccine Research. Pittsburgh, PA, USA.Universidade Federal do Rio de Janeiro. Instituto de Bioquímica Médica Leopoldo de Meis. Rio de Janeiro, RJ, Brasil.University of Pittsburgh. Center for Vaccine Research. Pittsburgh, PA, USA.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Pesagro-Rio. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clinica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo Goés. Laboratório de Glicobiologia de Eucariotos. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Bioquímica Médica Leopoldo de Meis. Rio de Janeiro, RJ, Brasil.University of Pittsburgh. Center for Vaccine Research. Pittsburgh, PA, USA / Fundação Oswaldo Cruz. Centro de Pesquisa Aggeu Magalhães. Laboratório de Virologia e Terapia Experimental. Recife, PE, Brasil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, Brasil.University of Pittsburgh. Center for Vaccine Research. Pittsburgh, PA, USA / Fondazione RiMED. Palermo, Italy.To exert their therapeutic action, probiotic Saccharomyces cerevisiae strains must survive harsh digestive environments. Lipid droplets accumulate in cells which undergo stress-inducing situations, supposedly having a protective role.We assessed lipid droplet levels, either naturally accumulated or induced in response to digestive challenges, of probiotic strains S. boulardii, S. cerevisiae A-905, S. cerevisiae Sc47 and S. cerevisiae L11, and of non-probiotic strains S. cerevisiae BY4741 and S. cerevisiae BY4743. Strains 905 and Sc47 had lower and higher lipid droplet levels, respectively, when compared to the remaining strains, showing that higher accumulation To exert their therapeutic action, probiotic Saccharomyces cerevisiae strains must survive harsh digestive environments. Lipid droplets accumulate in cells which undergo stress-inducing situations, supposedly having a protective role.We assessed lipid droplet levels, either naturally accumulated or induced in response to digestive challenges, of probiotic strains S. boulardii, S. cerevisiae A-905, S. cerevisiae Sc47 and S. cerevisiae L11, and of non-probiotic strains S. cerevisiae BY4741 and S. cerevisiae BY4743. Strains 905 and Sc47 had lower and higher lipid droplet levels, respectively, when compared to the remaining strains, showing that higher accumulation.Saccharomyces cerevisiae var boulardiiSaccharomyces cerevisiaeProbioticsLipid dropletsLipid dropletsStress resistanceinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/32573/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Zamith-Miranda_Daniel_etal_INI_2016.pdfve_Zamith-Miranda_Daniel_etal_INI_2016.pdfapplication/pdf846934https://www.arca.fiocruz.br/bitstream/icict/32573/2/ve_Zamith-Miranda_Daniel_etal_INI_2016.pdf94ded76067bfbc0e46407c8716299c1fMD52TEXTve_Zamith-Miranda_Daniel_etal_INI_2016.pdf.txtve_Zamith-Miranda_Daniel_etal_INI_2016.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Lipid droplet levels vary heterogeneously in responseto simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains
title Lipid droplet levels vary heterogeneously in responseto simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains
spellingShingle Lipid droplet levels vary heterogeneously in responseto simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains
Zamith-Miranda, Daniel
Saccharomyces cerevisiae var boulardii
Saccharomyces cerevisiae
Probiotics
Lipid droplets
Lipid droplets
Stress resistance
title_short Lipid droplet levels vary heterogeneously in responseto simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains
title_full Lipid droplet levels vary heterogeneously in responseto simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains
title_fullStr Lipid droplet levels vary heterogeneously in responseto simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains
title_full_unstemmed Lipid droplet levels vary heterogeneously in responseto simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains
title_sort Lipid droplet levels vary heterogeneously in responseto simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains
author Zamith-Miranda, Daniel
author_facet Zamith-Miranda, Daniel
Palma, Mariana L.
Matos, Gabriel S.
Schiebel, Johnathon G.
Maya-Monteiro, Clarissa M.
Aronovich, Marcos
Bozza, Patrícia T.
Bozza, Fernando A.
Nimrichter, Leonardo
Montero-Lomeli, Monica
Marques Jr., Ernesto T. A.
Martins, Flaviano S.
Douradinha, Bruno
author_role author
author2 Palma, Mariana L.
Matos, Gabriel S.
Schiebel, Johnathon G.
Maya-Monteiro, Clarissa M.
Aronovich, Marcos
Bozza, Patrícia T.
Bozza, Fernando A.
Nimrichter, Leonardo
Montero-Lomeli, Monica
Marques Jr., Ernesto T. A.
Martins, Flaviano S.
Douradinha, Bruno
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Zamith-Miranda, Daniel
Palma, Mariana L.
Matos, Gabriel S.
Schiebel, Johnathon G.
Maya-Monteiro, Clarissa M.
Aronovich, Marcos
Bozza, Patrícia T.
Bozza, Fernando A.
Nimrichter, Leonardo
Montero-Lomeli, Monica
Marques Jr., Ernesto T. A.
Martins, Flaviano S.
Douradinha, Bruno
dc.subject.en.pt_BR.fl_str_mv Saccharomyces cerevisiae var boulardii
Saccharomyces cerevisiae
Probiotics
Lipid droplets
Lipid droplets
Stress resistance
topic Saccharomyces cerevisiae var boulardii
Saccharomyces cerevisiae
Probiotics
Lipid droplets
Lipid droplets
Stress resistance
description 2020-04-12
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2019-04-18T12:42:23Z
dc.date.available.fl_str_mv 2019-04-18T12:42:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ZAMITH-MIRANDA, Daniel et al. Lipid droplet levels vary heterogeneously in response to simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains. Journal of Functional Foods, v. 21, p. 193-200, 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/32573
dc.identifier.issn.pt_BR.fl_str_mv 1756-4646
dc.identifier.doi.none.fl_str_mv 10.1016/j.jff.2015.12.013
dc.identifier.eissn.none.fl_str_mv 2214-9414
identifier_str_mv ZAMITH-MIRANDA, Daniel et al. Lipid droplet levels vary heterogeneously in response to simulated gastrointestinal stresses in different probiotic Saccharomyces cerevisiae strains. Journal of Functional Foods, v. 21, p. 193-200, 2016.
1756-4646
10.1016/j.jff.2015.12.013
2214-9414
url https://www.arca.fiocruz.br/handle/icict/32573
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/32573/2/ve_Zamith-Miranda_Daniel_etal_INI_2016.pdf
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