Clearing factor pancreático

Detalhes bibliográficos
Autor(a) principal: Póvoa Jr, Helion
Data de Publicação: 1974
Outros Autores: Marcondes, Neusa, Oliveira, Jorge M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/41885
Resumo: Dosou-se o "clearing factor" (lipase lipoproteica), em pâncreas de ratos normais após serem submetidos a algumas condições experimentais. As seguintes conclusões podem ser extraídas: a) O pãncreas é o órgão mais rico nesta enzima (8 vezes mais que o tecido adiposo, até então considerado o mais rico em CF); b) O jejum total de 48 horas diminui significamente a atividade de CF; c) O complamin, o derivado do ácido nicotínico, agindo sobre a arteriosclerose experimental, não afeta a atividade da enzima; d) O ácido épsilon-aminocapróico (AEAC) potente antagonista da heparina, inibe a ativdade do Cf pancreático; e) Ratos com arteriosclerose experimental apresentam níveis diminuídos desta enzima no pâncreas.
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spelling Póvoa Jr, HelionMarcondes, NeusaOliveira, Jorge M.2020-06-25T18:30:16Z2020-06-25T18:30:16Z1974PÓVOA JR. Clearing factor pancreático. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 72, n. 1, p. 21-29, 1972.0074-0276https://www.arca.fiocruz.br/handle/icict/4188510.1590/S0074-027619740001000041678-8060Dosou-se o "clearing factor" (lipase lipoproteica), em pâncreas de ratos normais após serem submetidos a algumas condições experimentais. As seguintes conclusões podem ser extraídas: a) O pãncreas é o órgão mais rico nesta enzima (8 vezes mais que o tecido adiposo, até então considerado o mais rico em CF); b) O jejum total de 48 horas diminui significamente a atividade de CF; c) O complamin, o derivado do ácido nicotínico, agindo sobre a arteriosclerose experimental, não afeta a atividade da enzima; d) O ácido épsilon-aminocapróico (AEAC) potente antagonista da heparina, inibe a ativdade do Cf pancreático; e) Ratos com arteriosclerose experimental apresentam níveis diminuídos desta enzima no pâncreas.Pancreatic lipoprotein lipase has been studied in pancreas of normal rat and after submitting these animals to several experiments. The conclusions are the follwing: a) pancreas is very rich in this enzyme (8 times more than adipose tissue). b)Total activation of 48 hours decreases significantty lipoprotein lipase ativity of pancreas. c) Complamin a, derivative of nicotinic acid (having some activity against) experimental atherogenesis), does not affect activity ofthe pancreatic enzyme.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, GB, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, GB, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, GB, Brasil.engFundação Oswaldo Cruz. 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dc.title.pt_BR.fl_str_mv Clearing factor pancreático
title Clearing factor pancreático
spellingShingle Clearing factor pancreático
Póvoa Jr, Helion
Lipase lipoproteica
Pãncreas
Ratos
Lipoprotein lipase
Pancreas
Rats
title_short Clearing factor pancreático
title_full Clearing factor pancreático
title_fullStr Clearing factor pancreático
title_full_unstemmed Clearing factor pancreático
title_sort Clearing factor pancreático
author Póvoa Jr, Helion
author_facet Póvoa Jr, Helion
Marcondes, Neusa
Oliveira, Jorge M.
author_role author
author2 Marcondes, Neusa
Oliveira, Jorge M.
author2_role author
author
dc.contributor.author.fl_str_mv Póvoa Jr, Helion
Marcondes, Neusa
Oliveira, Jorge M.
dc.subject.other.pt_BR.fl_str_mv Lipase lipoproteica
Pãncreas
Ratos
topic Lipase lipoproteica
Pãncreas
Ratos
Lipoprotein lipase
Pancreas
Rats
dc.subject.en.pt_BR.fl_str_mv Lipoprotein lipase
Pancreas
Rats
description Dosou-se o "clearing factor" (lipase lipoproteica), em pâncreas de ratos normais após serem submetidos a algumas condições experimentais. As seguintes conclusões podem ser extraídas: a) O pãncreas é o órgão mais rico nesta enzima (8 vezes mais que o tecido adiposo, até então considerado o mais rico em CF); b) O jejum total de 48 horas diminui significamente a atividade de CF; c) O complamin, o derivado do ácido nicotínico, agindo sobre a arteriosclerose experimental, não afeta a atividade da enzima; d) O ácido épsilon-aminocapróico (AEAC) potente antagonista da heparina, inibe a ativdade do Cf pancreático; e) Ratos com arteriosclerose experimental apresentam níveis diminuídos desta enzima no pâncreas.
publishDate 1974
dc.date.issued.fl_str_mv 1974
dc.date.accessioned.fl_str_mv 2020-06-25T18:30:16Z
dc.date.available.fl_str_mv 2020-06-25T18:30:16Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv PÓVOA JR. Clearing factor pancreático. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 72, n. 1, p. 21-29, 1972.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/41885
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02761974000100004
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv PÓVOA JR. Clearing factor pancreático. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 72, n. 1, p. 21-29, 1972.
0074-0276
10.1590/S0074-02761974000100004
1678-8060
url https://www.arca.fiocruz.br/handle/icict/41885
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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