Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/19434 |
Resumo: | Universidade do Estadol do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. |
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Borges, Juliana PereiraFrança, Guilherme de OliveiraCruz, Mariana DelgadoLanza, RômuloNascimento, Alessandro Rodrigues doLessa, Marcos Adriano2017-06-20T14:22:02Z2017-06-20T14:22:02Z2017BORGES, Juliana Pereira; et al. Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats. Motriz, v.23, Special issue, e101620, 2017.1980-6574https://www.arca.fiocruz.br/handle/icict/1943410.1590/S1980-6574201700SI0011engUniversidade Estadual PaulistaIsquemia e reperfusãoTreinamento de exercícios aeróbicosischemia and reperfusionaerobic exercise trainingLangendorffAerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in ratsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade do Estadol do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.Universidade do Estadol do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Abstract — Aim: To compare the amount of cardioprotection induced by a single exercise session with those achieved after an 8-week aerobic exercise training following ischemia reperfusion injury in rats. Methods: Twenty-five male Wistar rats (250-300g) were assigned into a group submitted to physical training (TR; n=12) or a single maximal exercise session (EXE; n=13). Following sedentarism or physical training (8 weeks, 5 sessions/wk, 1h/session at 70% of maximal speed) both groups performed a maximal exercise test. Then, groups were submitted to ischemia reperfusion injury (30 min/1h) through an isolated heart protocol, in which left ventricle developed pressure was measured. Results: The TR group presented greater maximal oxygen consumption compared to the EXE group (77.25±20.41 vs 41.32±25.86 ml/Kg/min; P=0.003). Regarding left ventricle developed pressure, no differences were detected between groups at baseline (TR: 89.78±24.40 vs EXE: 81.37±31.84 mmHg; P=0.48). However, after reperfusion, the TR group presented superior intraventricular pressure than EXE group (37.94±18.34 vs 21.59±13.67 mmHg; P=0.03). Conclusion: Eight-week aerobic training induced greater cardioprotection against ischemia reperfusion injury in rats compared to a single exercise session, due to an increased cardiac function. This suggests that exercise-induced cardioprotection is a multifactorial process that may involve different mediators according to the exercise duration.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/19434/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALmariana_cruz_etal_IOC_2017.pdfmariana_cruz_etal_IOC_2017.pdfapplication/pdf501995https://www.arca.fiocruz.br/bitstream/icict/19434/2/mariana_cruz_etal_IOC_2017.pdf7b349ec2dd9ad7e492102b10b4bd9390MD52TEXTmariana_cruz_etal_IOC_2017.pdf.txtmariana_cruz_etal_IOC_2017.pdf.txtExtracted texttext/plain24597https://www.arca.fiocruz.br/bitstream/icict/19434/3/mariana_cruz_etal_IOC_2017.pdf.txt45c8c0b4fbbad0e2f3af973de3b912e3MD53icict/194342018-08-15 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dc.title.pt_BR.fl_str_mv |
Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats |
title |
Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats |
spellingShingle |
Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats Borges, Juliana Pereira Isquemia e reperfusão Treinamento de exercícios aeróbicos ischemia and reperfusion aerobic exercise training Langendorff |
title_short |
Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats |
title_full |
Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats |
title_fullStr |
Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats |
title_full_unstemmed |
Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats |
title_sort |
Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats |
author |
Borges, Juliana Pereira |
author_facet |
Borges, Juliana Pereira França, Guilherme de Oliveira Cruz, Mariana Delgado Lanza, Rômulo Nascimento, Alessandro Rodrigues do Lessa, Marcos Adriano |
author_role |
author |
author2 |
França, Guilherme de Oliveira Cruz, Mariana Delgado Lanza, Rômulo Nascimento, Alessandro Rodrigues do Lessa, Marcos Adriano |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Borges, Juliana Pereira França, Guilherme de Oliveira Cruz, Mariana Delgado Lanza, Rômulo Nascimento, Alessandro Rodrigues do Lessa, Marcos Adriano |
dc.subject.other.pt_BR.fl_str_mv |
Isquemia e reperfusão Treinamento de exercícios aeróbicos |
topic |
Isquemia e reperfusão Treinamento de exercícios aeróbicos ischemia and reperfusion aerobic exercise training Langendorff |
dc.subject.en.pt_BR.fl_str_mv |
ischemia and reperfusion aerobic exercise training Langendorff |
description |
Universidade do Estadol do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. |
publishDate |
2017 |
dc.date.accessioned.fl_str_mv |
2017-06-20T14:22:02Z |
dc.date.available.fl_str_mv |
2017-06-20T14:22:02Z |
dc.date.issued.fl_str_mv |
2017 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BORGES, Juliana Pereira; et al. Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats. Motriz, v.23, Special issue, e101620, 2017. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/19434 |
dc.identifier.issn.pt_BR.fl_str_mv |
1980-6574 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S1980-6574201700SI0011 |
identifier_str_mv |
BORGES, Juliana Pereira; et al. Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats. Motriz, v.23, Special issue, e101620, 2017. 1980-6574 10.1590/S1980-6574201700SI0011 |
url |
https://www.arca.fiocruz.br/handle/icict/19434 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Universidade Estadual Paulista |
publisher.none.fl_str_mv |
Universidade Estadual Paulista |
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reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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FIOCRUZ |
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