Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats

Detalhes bibliográficos
Autor(a) principal: Borges, Juliana Pereira
Data de Publicação: 2017
Outros Autores: França, Guilherme de Oliveira, Cruz, Mariana Delgado, Lanza, Rômulo, Nascimento, Alessandro Rodrigues do, Lessa, Marcos Adriano
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/19434
Resumo: Universidade do Estadol do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
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spelling Borges, Juliana PereiraFrança, Guilherme de OliveiraCruz, Mariana DelgadoLanza, RômuloNascimento, Alessandro Rodrigues doLessa, Marcos Adriano2017-06-20T14:22:02Z2017-06-20T14:22:02Z2017BORGES, Juliana Pereira; et al. Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats. Motriz, v.23, Special issue, e101620, 2017.1980-6574https://www.arca.fiocruz.br/handle/icict/1943410.1590/S1980-6574201700SI0011engUniversidade Estadual PaulistaIsquemia e reperfusãoTreinamento de exercícios aeróbicosischemia and reperfusionaerobic exercise trainingLangendorffAerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in ratsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade do Estadol do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.Universidade do Estadol do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Abstract — Aim: To compare the amount of cardioprotection induced by a single exercise session with those achieved after an 8-week aerobic exercise training following ischemia reperfusion injury in rats. Methods: Twenty-five male Wistar rats (250-300g) were assigned into a group submitted to physical training (TR; n=12) or a single maximal exercise session (EXE; n=13). Following sedentarism or physical training (8 weeks, 5 sessions/wk, 1h/session at 70% of maximal speed) both groups performed a maximal exercise test. Then, groups were submitted to ischemia reperfusion injury (30 min/1h) through an isolated heart protocol, in which left ventricle developed pressure was measured. Results: The TR group presented greater maximal oxygen consumption compared to the EXE group (77.25±20.41 vs 41.32±25.86 ml/Kg/min; P=0.003). Regarding left ventricle developed pressure, no differences were detected between groups at baseline (TR: 89.78±24.40 vs EXE: 81.37±31.84 mmHg; P=0.48). However, after reperfusion, the TR group presented superior intraventricular pressure than EXE group (37.94±18.34 vs 21.59±13.67 mmHg; P=0.03). Conclusion: Eight-week aerobic training induced greater cardioprotection against ischemia reperfusion injury in rats compared to a single exercise session, due to an increased cardiac function. This suggests that exercise-induced cardioprotection is a multifactorial process that may involve different mediators according to the exercise duration.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/19434/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALmariana_cruz_etal_IOC_2017.pdfmariana_cruz_etal_IOC_2017.pdfapplication/pdf501995https://www.arca.fiocruz.br/bitstream/icict/19434/2/mariana_cruz_etal_IOC_2017.pdf7b349ec2dd9ad7e492102b10b4bd9390MD52TEXTmariana_cruz_etal_IOC_2017.pdf.txtmariana_cruz_etal_IOC_2017.pdf.txtExtracted texttext/plain24597https://www.arca.fiocruz.br/bitstream/icict/19434/3/mariana_cruz_etal_IOC_2017.pdf.txt45c8c0b4fbbad0e2f3af973de3b912e3MD53icict/194342018-08-15 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dc.title.pt_BR.fl_str_mv Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats
title Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats
spellingShingle Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats
Borges, Juliana Pereira
Isquemia e reperfusão
Treinamento de exercícios aeróbicos
ischemia and reperfusion
aerobic exercise training
Langendorff
title_short Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats
title_full Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats
title_fullStr Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats
title_full_unstemmed Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats
title_sort Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats
author Borges, Juliana Pereira
author_facet Borges, Juliana Pereira
França, Guilherme de Oliveira
Cruz, Mariana Delgado
Lanza, Rômulo
Nascimento, Alessandro Rodrigues do
Lessa, Marcos Adriano
author_role author
author2 França, Guilherme de Oliveira
Cruz, Mariana Delgado
Lanza, Rômulo
Nascimento, Alessandro Rodrigues do
Lessa, Marcos Adriano
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Borges, Juliana Pereira
França, Guilherme de Oliveira
Cruz, Mariana Delgado
Lanza, Rômulo
Nascimento, Alessandro Rodrigues do
Lessa, Marcos Adriano
dc.subject.other.pt_BR.fl_str_mv Isquemia e reperfusão
Treinamento de exercícios aeróbicos
topic Isquemia e reperfusão
Treinamento de exercícios aeróbicos
ischemia and reperfusion
aerobic exercise training
Langendorff
dc.subject.en.pt_BR.fl_str_mv ischemia and reperfusion
aerobic exercise training
Langendorff
description Universidade do Estadol do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
publishDate 2017
dc.date.accessioned.fl_str_mv 2017-06-20T14:22:02Z
dc.date.available.fl_str_mv 2017-06-20T14:22:02Z
dc.date.issued.fl_str_mv 2017
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BORGES, Juliana Pereira; et al. Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats. Motriz, v.23, Special issue, e101620, 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/19434
dc.identifier.issn.pt_BR.fl_str_mv 1980-6574
dc.identifier.doi.none.fl_str_mv 10.1590/S1980-6574201700SI0011
identifier_str_mv BORGES, Juliana Pereira; et al. Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats. Motriz, v.23, Special issue, e101620, 2017.
1980-6574
10.1590/S1980-6574201700SI0011
url https://www.arca.fiocruz.br/handle/icict/19434
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Estadual Paulista
publisher.none.fl_str_mv Universidade Estadual Paulista
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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