Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides

Detalhes bibliográficos
Autor(a) principal: Amorim, Gustavo Moreira
Data de Publicação: 2018
Outros Autores: Corbellini, João Paulo Niemeyer, Quintella, Danielle Carvalho, Cuzzi, Tullia, Ramos-e-Silva, Márcia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/31493
Resumo: Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Hospital Universitário Clementino Fraga Filho. Rio de Janeiro, RJ, Brasil / Universidade do Sul de Santa Catarina. Faculdade de Medicina. Outpatient clinic of Dermatology. Palhoça, SC, Brasil.
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spelling Amorim, Gustavo MoreiraCorbellini, João Paulo NiemeyerQuintella, Danielle CarvalhoCuzzi, TulliaRamos-e-Silva, Márcia2019-02-08T13:02:03Z2019-02-08T13:02:03Z2018AMORIM, Gustavo Moreira et al. Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides. Anais Brasileiros de Dermatologia, v. 93, n. 5, p. 680-685, 2018.0365-0596https://www.arca.fiocruz.br/handle/icict/3149310.1590/abd1806-4841.201871341806-4841engSociedade Brasileira de DermatologiaEvaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoidesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio de Janeiro. Faculdade de Medicina. Hospital Universitário Clementino Fraga Filho. Rio de Janeiro, RJ, Brasil / Universidade do Sul de Santa Catarina. Faculdade de Medicina. Outpatient clinic of Dermatology. Palhoça, SC, Brasil.Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Dermatology Division. Rio de Janeiro, RJ, Brasil.Hospital Federal de Bonsucesso. Pathology Division. Rio de Janeiro, RJ, Brazil / Universidade Federal do Rio de Janeiro. Department of Pathology. Rio de Janeiro, RJ, Brazil.Universidade Federal do Rio de Janeiro. Department of Pathology. Rio de Janeiro, RJ, Brazil / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Dermatology Division. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Discipline of Dermatology. Rio de Janeiro, RJ, Brazil.Background: Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma. TNMB system is the staging method used in MF, and it not only guides therapeutic management, but represents the main prognostic factor. In order to improve the prognostic evaluation, the Cutaneous Lymphoma International Prognostic Index (CLIPi) was proposed. Objective: To evaluate the performance of CLIPi score for prognostic analysis in patients with early stage MF. Methods: This is a retrospective cross-sectional observational study, with exploratory analysis. The outcome variables were disease progression and related death. Results: One hundred and two patients were stratified according to CLIPi score, being the majority classified as low risk. Patients with intermediate or high risk presented disease progression more frequently than those with low risk (PR: 1.2 / p =0.004 / 95%CI: 1.0 – 1.6). The same did not occur with the variable related death. In addition, survival rates were not consistent with risk stratification. Study Limitations: Small sample and its retrospective analysis. Conclusions: Since CLIPi score was proposed, four other studies that we could consult showed conflicting results, similar to the present study. Further studies are necessary for a recommendation of its use.LymphomaCutaneous lymphomaT-cellMycosis fungoidesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/31493/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALve_Amorim_gustavo_etal_INI_2018.pdfve_Amorim_gustavo_etal_INI_2018.pdfapplication/pdf279734https://www.arca.fiocruz.br/bitstream/icict/31493/2/ve_Amorim_gustavo_etal_INI_2018.pdf3388cad447fe2be1b8c79ac0ded6e891MD52TEXTve_Amorim_gustavo_etal_INI_2018.pdf.txtve_Amorim_gustavo_etal_INI_2018.pdf.txtExtracted texttext/plain29092https://www.arca.fiocruz.br/bitstream/icict/31493/3/ve_Amorim_gustavo_etal_INI_2018.pdf.txt9c6fb53340c88f7b6f3b88d4a6c603c3MD53icict/314932019-02-10 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dc.title.pt_BR.fl_str_mv Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides
title Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides
spellingShingle Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides
Amorim, Gustavo Moreira
Lymphoma
Cutaneous lymphoma
T-cell
Mycosis fungoides
title_short Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides
title_full Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides
title_fullStr Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides
title_full_unstemmed Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides
title_sort Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides
author Amorim, Gustavo Moreira
author_facet Amorim, Gustavo Moreira
Corbellini, João Paulo Niemeyer
Quintella, Danielle Carvalho
Cuzzi, Tullia
Ramos-e-Silva, Márcia
author_role author
author2 Corbellini, João Paulo Niemeyer
Quintella, Danielle Carvalho
Cuzzi, Tullia
Ramos-e-Silva, Márcia
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Amorim, Gustavo Moreira
Corbellini, João Paulo Niemeyer
Quintella, Danielle Carvalho
Cuzzi, Tullia
Ramos-e-Silva, Márcia
dc.subject.en.pt_BR.fl_str_mv Lymphoma
Cutaneous lymphoma
T-cell
Mycosis fungoides
topic Lymphoma
Cutaneous lymphoma
T-cell
Mycosis fungoides
description Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Hospital Universitário Clementino Fraga Filho. Rio de Janeiro, RJ, Brasil / Universidade do Sul de Santa Catarina. Faculdade de Medicina. Outpatient clinic of Dermatology. Palhoça, SC, Brasil.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-02-08T13:02:03Z
dc.date.available.fl_str_mv 2019-02-08T13:02:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv AMORIM, Gustavo Moreira et al. Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides. Anais Brasileiros de Dermatologia, v. 93, n. 5, p. 680-685, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/31493
dc.identifier.issn.pt_BR.fl_str_mv 0365-0596
dc.identifier.doi.none.fl_str_mv 10.1590/abd1806-4841.20187134
dc.identifier.eissn.none.fl_str_mv 1806-4841
identifier_str_mv AMORIM, Gustavo Moreira et al. Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides. Anais Brasileiros de Dermatologia, v. 93, n. 5, p. 680-685, 2018.
0365-0596
10.1590/abd1806-4841.20187134
1806-4841
url https://www.arca.fiocruz.br/handle/icict/31493
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/31493/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/31493/2/ve_Amorim_gustavo_etal_INI_2018.pdf
https://www.arca.fiocruz.br/bitstream/icict/31493/3/ve_Amorim_gustavo_etal_INI_2018.pdf.txt
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