Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts

Detalhes bibliográficos
Autor(a) principal: Marliére, Newmar Pinto
Data de Publicação: 2021
Outros Autores: Lorenzo, Marcelo Gustavo, Guarneri, Alessandra Aparecida
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/52017
Resumo: Vector Behavior and Pathogen Interaction Group. René Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil.
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spelling Marliére, Newmar PintoLorenzo, Marcelo GustavoGuarneri, Alessandra Aparecida2022-04-04T17:30:43Z2022-04-04T17:30:43Z2021MARLIÉRE, Newmar Pinto; LORENZO, Marcelo Gustavo; GUARNERI, Alessandra Aparecida. Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts. PLoS Negl Trop Dis., v. 15, n. 7, e0009570, 2021. doi: 10.1371/journal.pntd.0009570.1935-2735https://www.arca.fiocruz.br/handle/icict/5201710.1371/journal.pntd.0009570engPublic Library of ScienceTrypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hostsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleVector Behavior and Pathogen Interaction Group. René Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil.Vector Behavior and Pathogen Interaction Group. René Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil.Vector Behavior and Pathogen Interaction Group. René Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil.Triatomine bugs aggregate with conspecifics inside shelters during daylight hours. At dusk, they leave their refuges searching for hosts on which to blood feed. After finding a host, triatomines face the threat of being killed, because hosts often prey on them. As it is known that many parasites induce the predation of intermediate hosts to promote transmission, and that ingestion of Trypanosoma cruzi-infected bugs represents a very effective means for mammal infection, we hypothesized that trypanosomes induce infected bugs to take increased risk, and, as a consequence, be predated when approaching a host. Therefore, we evaluated whether the predation risk and predation rates endured by Rhodnius prolixus increase when infected with T. cruzi. Assays were performed in square glass arenas offering one central refuge to infected and uninfected 5th instar nymphs. A caged mouse was introduced in each arena after a three-day acclimation interval to activate sheltered insects and induce them to approach it. As hypothesized, a significantly higher proportion of infected insects was predated when compared with uninfected ones (36% and 19%, respectively). Indeed, T. cruzi-infected bugs took higher risk (Approximation Index = 0.642) when compared with healthy ones (Approximation Index = 0.302) and remained outside the shelters when the host was removed from the arena. Our results show that infection by T. cruzi induces bugs to assume higher risk and endure higher predation rates. We reveal a hitherto unknown trypanosome-vector interaction process that increases infected bug predation, promoting increased rates of robust oral transmission. The significant consequences of the mechanism revealed here make it a fundamental component for the resilient maintenance of sylvatic, peridomestic and domestic cyclesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/52017/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALTrypanosoma cruzi-infected Rhodnius pro... parasite transmission to mammal hosts.pdfTrypanosoma cruzi-infected Rhodnius pro... parasite transmission to mammal hosts.pdfapplication/pdf629869https://www.arca.fiocruz.br/bitstream/icict/52017/2/Trypanosoma%20cruzi-infected%20Rhodnius%20pro...%20parasite%20transmission%20to%20mammal%20hosts.pdf034443f6f4cc35546908aebe76750feaMD52icict/520172022-04-04 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dc.title.pt_BR.fl_str_mv Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts
title Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts
spellingShingle Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts
Marliére, Newmar Pinto
title_short Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts
title_full Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts
title_fullStr Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts
title_full_unstemmed Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts
title_sort Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts
author Marliére, Newmar Pinto
author_facet Marliére, Newmar Pinto
Lorenzo, Marcelo Gustavo
Guarneri, Alessandra Aparecida
author_role author
author2 Lorenzo, Marcelo Gustavo
Guarneri, Alessandra Aparecida
author2_role author
author
dc.contributor.author.fl_str_mv Marliére, Newmar Pinto
Lorenzo, Marcelo Gustavo
Guarneri, Alessandra Aparecida
description Vector Behavior and Pathogen Interaction Group. René Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2022-04-04T17:30:43Z
dc.date.available.fl_str_mv 2022-04-04T17:30:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MARLIÉRE, Newmar Pinto; LORENZO, Marcelo Gustavo; GUARNERI, Alessandra Aparecida. Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts. PLoS Negl Trop Dis., v. 15, n. 7, e0009570, 2021. doi: 10.1371/journal.pntd.0009570.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/52017
dc.identifier.issn.pt_BR.fl_str_mv 1935-2735
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pntd.0009570
identifier_str_mv MARLIÉRE, Newmar Pinto; LORENZO, Marcelo Gustavo; GUARNERI, Alessandra Aparecida. Trypanosoma cruzi-infected Rhodnius prolixus endure increased predation facilitating parasite transmission to mammal hosts. PLoS Negl Trop Dis., v. 15, n. 7, e0009570, 2021. doi: 10.1371/journal.pntd.0009570.
1935-2735
10.1371/journal.pntd.0009570
url https://www.arca.fiocruz.br/handle/icict/52017
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
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collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/52017/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/52017/2/Trypanosoma%20cruzi-infected%20Rhodnius%20pro...%20parasite%20transmission%20to%20mammal%20hosts.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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