mgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil

Detalhes bibliográficos
Autor(a) principal: Aires, Caio Augusto Martins
Data de Publicação: 2016
Outros Autores: Pereira, Polyana Silva, Asensi, Marise Dutra, Assef, Ana Paula D'Alincourt Carvalho
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/17983
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.
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spelling Aires, Caio Augusto MartinsPereira, Polyana SilvaAsensi, Marise DutraAssef, Ana Paula D'Alincourt Carvalho2017-03-09T13:30:09Z2017-03-09T13:30:09Z2016AIRES, Caio Augusto Martins; et al. MgrB mutations mediating polymyxin B resistance in Klebsiella pneumoniae isolates from rectal surveillance swabs in Brazil. Antimicrobial Agents and Chemotherapy, v.61, n.3, 15p, Sept. 2016.0066-4804https://www.arca.fiocruz.br/handle/icict/1798310.1128/AAC.01456-161098-6596engAmerican Society for MicrobiologyKlebsiella pneumoniaePolimixina BTipagem MolecularResistência a medicamentosPolymyxin B resistanceKlebsiella pneumoniaeMolecular typingMrgB mutationmgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.We aimed to investigate polymyxin B (PMB) resistance and its molecular mechanisms in 126 Klebsiella pneumoniae isolates from rectal swabs in Brazil. Ten isolates exhibited PMB resistance with interruption of mgrB gene by insertion sequences or missense mutations. Most of the PMB-resistant isolates harbored blaKPC-2 (n = 8) and belonged to clonal complex 258 (CC258) (n = 7). 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dc.title.pt_BR.fl_str_mv mgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil
title mgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil
spellingShingle mgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil
Aires, Caio Augusto Martins
Klebsiella pneumoniae
Polimixina B
Tipagem Molecular
Resistência a medicamentos
Polymyxin B resistance
Klebsiella pneumoniae
Molecular typing
MrgB mutation
title_short mgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil
title_full mgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil
title_fullStr mgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil
title_full_unstemmed mgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil
title_sort mgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil
author Aires, Caio Augusto Martins
author_facet Aires, Caio Augusto Martins
Pereira, Polyana Silva
Asensi, Marise Dutra
Assef, Ana Paula D'Alincourt Carvalho
author_role author
author2 Pereira, Polyana Silva
Asensi, Marise Dutra
Assef, Ana Paula D'Alincourt Carvalho
author2_role author
author
author
dc.contributor.author.fl_str_mv Aires, Caio Augusto Martins
Pereira, Polyana Silva
Asensi, Marise Dutra
Assef, Ana Paula D'Alincourt Carvalho
dc.subject.other.pt_BR.fl_str_mv Klebsiella pneumoniae
Polimixina B
Tipagem Molecular
Resistência a medicamentos
topic Klebsiella pneumoniae
Polimixina B
Tipagem Molecular
Resistência a medicamentos
Polymyxin B resistance
Klebsiella pneumoniae
Molecular typing
MrgB mutation
dc.subject.en.pt_BR.fl_str_mv Polymyxin B resistance
Klebsiella pneumoniae
Molecular typing
MrgB mutation
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2017-03-09T13:30:09Z
dc.date.available.fl_str_mv 2017-03-09T13:30:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv AIRES, Caio Augusto Martins; et al. MgrB mutations mediating polymyxin B resistance in Klebsiella pneumoniae isolates from rectal surveillance swabs in Brazil. Antimicrobial Agents and Chemotherapy, v.61, n.3, 15p, Sept. 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/17983
dc.identifier.issn.pt_BR.fl_str_mv 0066-4804
dc.identifier.doi.none.fl_str_mv 10.1128/AAC.01456-16
dc.identifier.eissn.none.fl_str_mv 1098-6596
identifier_str_mv AIRES, Caio Augusto Martins; et al. MgrB mutations mediating polymyxin B resistance in Klebsiella pneumoniae isolates from rectal surveillance swabs in Brazil. Antimicrobial Agents and Chemotherapy, v.61, n.3, 15p, Sept. 2016.
0066-4804
10.1128/AAC.01456-16
1098-6596
url https://www.arca.fiocruz.br/handle/icict/17983
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv American Society for Microbiology
publisher.none.fl_str_mv American Society for Microbiology
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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