Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database

Detalhes bibliográficos
Autor(a) principal: Reis, Erika Cardoso dos
Data de Publicação: 2023
Outros Autores: Monteiro, Elma Lúcia de Freitas, Meneguci, Joilson, Rodrigues, Phillipe, Palma, Alexandre, Virtuoso Junior, Jair Sindra, Passos, Sonia Regina Lambert, Santos, Maria Angelica Borges dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/60982
Resumo: This study was financed in part by the Pan American Health Organization (PAHO) and the Coordination for the Improvement of Higher Education Personnel (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES) - Finance Code 001.
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spelling Reis, Erika Cardoso dosMonteiro, Elma Lúcia de FreitasMeneguci, JoilsonRodrigues, PhillipePalma, AlexandreVirtuoso Junior, Jair SindraPassos, Sonia Regina LambertSantos, Maria Angelica Borges dos2023-10-29T16:05:42Z2023-10-29T16:05:42Z2023REIS, Erika Cardoso dos et al. Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database. BMC Public Health, v. 23, p. 1-11, Aug. 2023.1471-2458https://www.arca.fiocruz.br/handle/icict/6098210.1186/s12889-023-16218-11471-2458This study was financed in part by the Pan American Health Organization (PAHO) and the Coordination for the Improvement of Higher Education Personnel (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES) - Finance Code 001.Universidade Federal de Ouro Preto. Escola de Nutrição, Departamento de Nutrição Clínica e Social. Ouro Preto, MG, Brazil.Universidade Federal do Triângulo Mineiro. Programa de Pós Graduação em Atenção à Saúde. Uberaba, MG, Brazil.Universidade Federal do Triângulo Mineiro. Programa de Pós Graduação em Atenção à Saúde. Uberaba, MG, Brazil.Universidade Federal do Rio de Janeiro. Escola de Educação Física e Desportos. Rio de Janeiro, RJ, Brazil.Universidade Federal do Triângulo Mineiro. Programa de Pós Graduação em Atenção à Saúde. Uberaba, MG, Brazil.Universidade Federal do Triângulo Mineiro. Programa de Pós Graduação em Atenção à Saúde. Uberaba, MG, Brazil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brazil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brazil.Previous studies have shown that associations between obesity and other comorbidities favor worse outcomes in COVID-19. However, it is not clear how these factors interrelate and whether effects on men and women differ. We conducted an observational, cross-sectional study using a national COVID-19 inpatient database. We studied differences in direct and indirect effects of obesity and comorbidities according to sex and body mass index (BMI) categories in hospitalized COVID-19 patients in Brazil using path analysis models and logistic regression. For men, path analysis showed a direct association between BMI and death and a negative correlation of death and chronic cardiovascular disease (CCD). For women, the association of BMI and death was indirect, mediated by admission to the ICU and comorbidities and association with CCD was non-significant. In the logistic regression analyses, there was a positive association between death and BMI, age, diabetes mellitus, kidney and lung diseases and ICU admission. We highlight the need to consider the distinct impact of obesity and sex on COVID-19, of monitoring of BMI and of the design for specific male-targeted approaches to manage obesity.engBioMed CentralBody mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national databaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleCOVID-19ObesityPandemicsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/60982/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALve_Erika_Reis_etal_ENSP_INI_2023.pdfve_Erika_Reis_etal_ENSP_INI_2023.pdfapplication/pdf1483888https://www.arca.fiocruz.br/bitstream/icict/60982/2/ve_Erika_Reis_etal_ENSP_INI_2023.pdfd928b723ef5d969739c203f3c0ae82afMD52icict/609822023-10-29 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dc.title.en_US.fl_str_mv Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database
title Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database
spellingShingle Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database
Reis, Erika Cardoso dos
COVID-19
Obesity
Pandemics
title_short Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database
title_full Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database
title_fullStr Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database
title_full_unstemmed Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database
title_sort Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database
author Reis, Erika Cardoso dos
author_facet Reis, Erika Cardoso dos
Monteiro, Elma Lúcia de Freitas
Meneguci, Joilson
Rodrigues, Phillipe
Palma, Alexandre
Virtuoso Junior, Jair Sindra
Passos, Sonia Regina Lambert
Santos, Maria Angelica Borges dos
author_role author
author2 Monteiro, Elma Lúcia de Freitas
Meneguci, Joilson
Rodrigues, Phillipe
Palma, Alexandre
Virtuoso Junior, Jair Sindra
Passos, Sonia Regina Lambert
Santos, Maria Angelica Borges dos
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Reis, Erika Cardoso dos
Monteiro, Elma Lúcia de Freitas
Meneguci, Joilson
Rodrigues, Phillipe
Palma, Alexandre
Virtuoso Junior, Jair Sindra
Passos, Sonia Regina Lambert
Santos, Maria Angelica Borges dos
dc.subject.en.en_US.fl_str_mv COVID-19
Obesity
Pandemics
topic COVID-19
Obesity
Pandemics
description This study was financed in part by the Pan American Health Organization (PAHO) and the Coordination for the Improvement of Higher Education Personnel (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES) - Finance Code 001.
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-10-29T16:05:42Z
dc.date.available.fl_str_mv 2023-10-29T16:05:42Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv REIS, Erika Cardoso dos et al. Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database. BMC Public Health, v. 23, p. 1-11, Aug. 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/60982
dc.identifier.issn.en_US.fl_str_mv 1471-2458
dc.identifier.doi.none.fl_str_mv 10.1186/s12889-023-16218-1
dc.identifier.eissn.none.fl_str_mv 1471-2458
identifier_str_mv REIS, Erika Cardoso dos et al. Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database. BMC Public Health, v. 23, p. 1-11, Aug. 2023.
1471-2458
10.1186/s12889-023-16218-1
url https://www.arca.fiocruz.br/handle/icict/60982
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/60982/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/60982/2/ve_Erika_Reis_etal_ENSP_INI_2023.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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