Zika virus infection in pregnant women in Rio de Janeiro
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2016 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/17780 |
Resumo: | Artigo liberado em acesso aberto como parte do acordo para tornar público todos os dados produzidos sobre o vírus zika - Compartilhamento de dados em emergências de saúde pública - http://www.wellcome.ac.uk/News/Media-office/Press-releases/2016/WTP060169.htm |
| id |
CRUZ_891bfa374656cfc7595baa0542c8e804 |
|---|---|
| oai_identifier_str |
oai:www.arca.fiocruz.br:icict/17780 |
| network_acronym_str |
CRUZ |
| network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| repository_id_str |
2135 |
| spelling |
Brasil, PatríciaPereira Jr., José P.Moreira, M. E.Nogueira, Rita M. RibeiroDamasceno, LuanaWakimoto, MayumiRabello, R. S.Valderramos, Stephanie G.Halai, U. A.Salles, Tania Regina Dias SaadZin, A. A.Horovitz, D.Daltro, P.Boechat, M.Gabaglia, Claudia RajaSequeira, Patrícia de Carvalho dePilotto, J. H.Medialdea-Carrera, R.Cunha, Denise Cotrim daCarvalho, Liege M. Abreu dePone, M.Siqueira, André MachadoCalvet, Guilherme A.Baião, Ana E. RodriguesNeves, Elizabeth S.Carvalho, Paulo R. Nassar deHasue, R. H.Marschik, P. B.Einspieler, C.Janzen, CarlaCherry, James D.Filippis, Ana M. Bispo deNielsen-Saines, Karin2017-02-09T17:54:26Z2017-02-09T17:54:26Z2016BRASIL, Patrícia et al. Zika virus infection in pregnant women in Rio de Janeiro. The New England Journal of Medicine, Massachusetts, v. 375, n. 24, p. 2321-2334, 15 Dec. 2016.0028-4793https://www.arca.fiocruz.br/handle/icict/1778010.1056/NEJMoa16024121533-4406Artigo liberado em acesso aberto como parte do acordo para tornar público todos os dados produzidos sobre o vírus zika - Compartilhamento de dados em emergências de saúde pública - http://www.wellcome.ac.uk/News/Media-office/Press-releases/2016/WTP060169.htmVersão preliminar - handle https://www.arca.fiocruz.br/handle/icict/13063Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.David Geffen UCLA School of Medicine, Los Angeles, EUA.David Geffen UCLA School of Medicine, Los Angeles, EUA.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.David Geffen UCLA School of Medicine, Los Angeles, EUA.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Biomedical Research Institute of Southern California. Oceanside, California, EUA.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Universidade de São Paulo. Faculdade de Medicina. São Paulo, SP.Karolinska Institutet, Stockholm.Medical University of Graz, Graz, Austria.David Geffen UCLA School of Medicine, Los Angeles, EUA.David Geffen UCLA School of Medicine, Los Angeles, EUA.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.David Geffen UCLA School of Medicine, Los Angeles, EUA.BACKGROUND: Zika virus (ZIKV) has been linked to central nervous system malformations in fetuses. To characterize the spectrum of ZIKV disease in pregnant women and infants, we followed patients in Rio de Janeiro to describe clinical manifestations in mothers and repercussions of acute ZIKV infection in infants. METHODS: We enrolled pregnant women in whom a rash had developed within the previous 5 days and tested blood and urine specimens for ZIKV by reverse-transcriptase–polymerasechain-reaction assays. We followed women prospectively to obtain data on pregnancy and infant outcomes. RESULTS: A total of 345 women were enrolled from September 2015 through May 2016; of these, 182 women (53%) tested positive for ZIKV in blood, urine, or both. The timing of acute ZIKV infection ranged from 6 to 39 weeks of gestation. Predominant maternal clinical features included a pruritic descending macular or maculopapular rash, arthralgias, conjunctival injection, and headache; 27% had fever (short-term and low-grade). By July 2016, a total of 134 ZIKV-affected pregnancies and 73 ZIKV-unaffected pregnancies had reached completion, with outcomes known for 125 ZIKV-affected and 61 ZIKV unaffected pregnancies. Infection with chikungunya virus was identified in 42% of women without ZIKV infection versus 3% of women with ZIKV infection (P<0.001). Rates of fetal death were 7% in both groups; overall adverse outcomes were 46% among offspring of ZIKV-positive women versus 11.5% among offspring of ZIKV-negative women (P<0.001). Among 117 live infants born to 116 ZIKV-positive women, 42% were found to have grossly abnormal clinical or brain imaging findings or both, including 4 infants with microcephaly. Adverse outcomes were noted regardless of the trimester during which the women were infected with ZIKV (55% of pregnancies had adverse outcomes after maternal infection in the first trimester, 52% after infection in the second trimester, and 29% after infection in the third trimester). CONCLUSIONS: Despite mild clinical symptoms in the mother, ZIKV infection during pregnancy is deleterious to the fetus and is associated with fetal death, fetal growth restriction, and a spectrum of central nervous system abnormalities. (Funded by Ministério da Saúde do Brasil and others.).engMassachusetts Medical SocietyVírus ZikaMicrocefaliaDoença ZIKV na gravidezAedes aegyptiZika VirusMicrocephalyZIKV disease in pregnancyAedes aegyptiAedesMicrocefaliaZika virus infection in pregnant women in Rio de Janeiroinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/17780/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALZika Virus Infection in Pregnant Women in Rio de Janeiro.pdfZika Virus Infection in Pregnant Women in Rio de Janeiro.pdfapplication/pdf469292https://www.arca.fiocruz.br/bitstream/icict/17780/2/Zika%20Virus%20Infection%20in%20Pregnant%20Women%20in%20Rio%20de%20Janeiro.pdf1690c1bd4e969661795a93985558eb03MD52TEXTZika Virus Infection in Pregnant Women in Rio de Janeiro.pdf.txtZika Virus Infection in Pregnant Women in Rio de Janeiro.pdf.txtExtracted texttext/plain55462https://www.arca.fiocruz.br/bitstream/icict/17780/3/Zika%20Virus%20Infection%20in%20Pregnant%20Women%20in%20Rio%20de%20Janeiro.pdf.txt5095a4f12e1bbb139963de574de721c8MD53icict/177802023-09-05 10:02:16.403oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-05T13:02:16Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.en.fl_str_mv |
Zika virus infection in pregnant women in Rio de Janeiro |
| title |
Zika virus infection in pregnant women in Rio de Janeiro |
| spellingShingle |
Zika virus infection in pregnant women in Rio de Janeiro Brasil, Patrícia Vírus Zika Microcefalia Doença ZIKV na gravidez Aedes aegypti Zika Virus Microcephaly ZIKV disease in pregnancy Aedes aegypti Aedes Microcefalia |
| title_short |
Zika virus infection in pregnant women in Rio de Janeiro |
| title_full |
Zika virus infection in pregnant women in Rio de Janeiro |
| title_fullStr |
Zika virus infection in pregnant women in Rio de Janeiro |
| title_full_unstemmed |
Zika virus infection in pregnant women in Rio de Janeiro |
| title_sort |
Zika virus infection in pregnant women in Rio de Janeiro |
| author |
Brasil, Patrícia |
| author_facet |
Brasil, Patrícia Pereira Jr., José P. Moreira, M. E. Nogueira, Rita M. Ribeiro Damasceno, Luana Wakimoto, Mayumi Rabello, R. S. Valderramos, Stephanie G. Halai, U. A. Salles, Tania Regina Dias Saad Zin, A. A. Horovitz, D. Daltro, P. Boechat, M. Gabaglia, Claudia Raja Sequeira, Patrícia de Carvalho de Pilotto, J. H. Medialdea-Carrera, R. Cunha, Denise Cotrim da Carvalho, Liege M. Abreu de Pone, M. Siqueira, André Machado Calvet, Guilherme A. Baião, Ana E. Rodrigues Neves, Elizabeth S. Carvalho, Paulo R. Nassar de Hasue, R. H. Marschik, P. B. Einspieler, C. Janzen, Carla Cherry, James D. Filippis, Ana M. Bispo de Nielsen-Saines, Karin |
| author_role |
author |
| author2 |
Pereira Jr., José P. Moreira, M. E. Nogueira, Rita M. Ribeiro Damasceno, Luana Wakimoto, Mayumi Rabello, R. S. Valderramos, Stephanie G. Halai, U. A. Salles, Tania Regina Dias Saad Zin, A. A. Horovitz, D. Daltro, P. Boechat, M. Gabaglia, Claudia Raja Sequeira, Patrícia de Carvalho de Pilotto, J. H. Medialdea-Carrera, R. Cunha, Denise Cotrim da Carvalho, Liege M. Abreu de Pone, M. Siqueira, André Machado Calvet, Guilherme A. Baião, Ana E. Rodrigues Neves, Elizabeth S. Carvalho, Paulo R. Nassar de Hasue, R. H. Marschik, P. B. Einspieler, C. Janzen, Carla Cherry, James D. Filippis, Ana M. Bispo de Nielsen-Saines, Karin |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Brasil, Patrícia Pereira Jr., José P. Moreira, M. E. Nogueira, Rita M. Ribeiro Damasceno, Luana Wakimoto, Mayumi Rabello, R. S. Valderramos, Stephanie G. Halai, U. A. Salles, Tania Regina Dias Saad Zin, A. A. Horovitz, D. Daltro, P. Boechat, M. Gabaglia, Claudia Raja Sequeira, Patrícia de Carvalho de Pilotto, J. H. Medialdea-Carrera, R. Cunha, Denise Cotrim da Carvalho, Liege M. Abreu de Pone, M. Siqueira, André Machado Calvet, Guilherme A. Baião, Ana E. Rodrigues Neves, Elizabeth S. Carvalho, Paulo R. Nassar de Hasue, R. H. Marschik, P. B. Einspieler, C. Janzen, Carla Cherry, James D. Filippis, Ana M. Bispo de Nielsen-Saines, Karin |
| dc.subject.other.pt_BR.fl_str_mv |
Vírus Zika Microcefalia Doença ZIKV na gravidez Aedes aegypti |
| topic |
Vírus Zika Microcefalia Doença ZIKV na gravidez Aedes aegypti Zika Virus Microcephaly ZIKV disease in pregnancy Aedes aegypti Aedes Microcefalia |
| dc.subject.en.en.fl_str_mv |
Zika Virus Microcephaly ZIKV disease in pregnancy Aedes aegypti |
| dc.subject.decs.en.fl_str_mv |
Aedes Microcefalia |
| description |
Artigo liberado em acesso aberto como parte do acordo para tornar público todos os dados produzidos sobre o vírus zika - Compartilhamento de dados em emergências de saúde pública - http://www.wellcome.ac.uk/News/Media-office/Press-releases/2016/WTP060169.htm |
| publishDate |
2016 |
| dc.date.issued.fl_str_mv |
2016 |
| dc.date.accessioned.fl_str_mv |
2017-02-09T17:54:26Z |
| dc.date.available.fl_str_mv |
2017-02-09T17:54:26Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
BRASIL, Patrícia et al. Zika virus infection in pregnant women in Rio de Janeiro. The New England Journal of Medicine, Massachusetts, v. 375, n. 24, p. 2321-2334, 15 Dec. 2016. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/17780 |
| dc.identifier.issn.pt_BR.fl_str_mv |
0028-4793 |
| dc.identifier.doi.pt_BR.fl_str_mv |
10.1056/NEJMoa1602412 |
| dc.identifier.eissn.pt_BR.fl_str_mv |
1533-4406 |
| identifier_str_mv |
BRASIL, Patrícia et al. Zika virus infection in pregnant women in Rio de Janeiro. The New England Journal of Medicine, Massachusetts, v. 375, n. 24, p. 2321-2334, 15 Dec. 2016. 0028-4793 10.1056/NEJMoa1602412 1533-4406 |
| url |
https://www.arca.fiocruz.br/handle/icict/17780 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Massachusetts Medical Society |
| publisher.none.fl_str_mv |
Massachusetts Medical Society |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
| instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
| reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/17780/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/17780/2/Zika%20Virus%20Infection%20in%20Pregnant%20Women%20in%20Rio%20de%20Janeiro.pdf https://www.arca.fiocruz.br/bitstream/icict/17780/3/Zika%20Virus%20Infection%20in%20Pregnant%20Women%20in%20Rio%20de%20Janeiro.pdf.txt |
| bitstream.checksum.fl_str_mv |
5a560609d32a3863062d77ff32785d58 1690c1bd4e969661795a93985558eb03 5095a4f12e1bbb139963de574de721c8 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1813009183471042560 |