Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil

Detalhes bibliográficos
Autor(a) principal: Pinto, Gabryela
Data de Publicação: 2021
Outros Autores: LIma, Lorena, Pedra, Thaís, Assumpção, Adriana, Morgado, Sergio, Mascarenhas, Luiz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/51093
Resumo: Hospital São Francisco de Assis. Comissão de Controle de Infecção Hospitalar. Rio de Janeiro, RJ, Brasil.
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spelling Pinto, GabryelaLIma, LorenaPedra, ThaísAssumpção, AdrianaMorgado, SergioMascarenhas, Luiz2022-02-08T18:43:48Z2022-02-08T18:43:48Z2021PINTO, Gabriela et al. Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil. Access Microbiology, v. 3, n. 8, p. 1-4, 6 Aug. 2021.2516-8290https://www.arca.fiocruz.br/handle/icict/5109310.1099/acmi.0.0002502516-8290engMicrobiology SocietyCOVID-19CoinfecçãoFungemiaSaccharomycesSepseCOVID-19CoinfectionFungaemiaSaccharomycesSepsisBloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHospital São Francisco de Assis. Comissão de Controle de Infecção Hospitalar. Rio de Janeiro, RJ, Brasil.Hospital São Francisco de Assis. Comissão de Controle de Infecção Hospitalar. Rio de Janeiro, RJ, Brasil.Hospital São Francisco de Assis. Comissão de Controle de Infecção Hospitalar. Rio de Janeiro, RJ, Brasil.Hospital São Francisco de Assis. Comissão de Controle de Infecção Hospitalar. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil.Hospital São Francisco de Assis. Comissão de Controle de Infecção Hospitalar. Rio de Janeiro, RJ, Brasil.Care-related infections (CRIs) have a negative impact on the morbidity and mortality of patients in intensive care. Among them, fungal infections (e.g. Candida spp. and Aspergillus spp.) have high mortality in critically ill patients, particularly those with acute respiratory distress syndrome (ARDS) and immunosuppression. Coronavirus disease 2019 (COVID-19) causes severe respiratory changes and deregulation of the immune system. Here, we describe a case of fungal infection in an intensive care unit (ICU) patient with COVID-19 caused by Saccharomyces cerevisiae, a yeast widely used in the baking and wine production industries. It is also used as a probiotic, both for prevention and as adjunctive therapy in patients with diarrhoea. The patient was admitted to the ICU with a diagnosis of COVID-19, respiratory failure, complications of ARDS and renal failure, and was being treated with antibiotics and vasoactive amines. Later, the patient had diarrhoea and, after supplementation with Saccharomyces, he developed a bloodstream infection with Saccharomyces. The patient died after 61days of hospitalization due to thrombocytopenia and bleeding. This case report suggests avoiding the use of probiotics in intensive care patients under the administration of antibiotics and amines, and with damage to the intestinal mucosa and immunodeficiency caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), since these factors could favour the translocation of fungi.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/51093/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALSergio_Morgado_etal_IOC_2021.pdfSergio_Morgado_etal_IOC_2021.pdfapplication/pdf182038https://www.arca.fiocruz.br/bitstream/icict/51093/2/Sergio_Morgado_etal_IOC_2021.pdfd2ded7870b0ef84cc5ddfdad31c69be9MD52icict/510932023-09-14 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dc.title.en_US.fl_str_mv Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil
title Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil
spellingShingle Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil
Pinto, Gabryela
COVID-19
Coinfecção
Fungemia
Saccharomyces
Sepse
COVID-19
Coinfection
Fungaemia
Saccharomyces
Sepsis
title_short Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil
title_full Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil
title_fullStr Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil
title_full_unstemmed Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil
title_sort Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil
author Pinto, Gabryela
author_facet Pinto, Gabryela
LIma, Lorena
Pedra, Thaís
Assumpção, Adriana
Morgado, Sergio
Mascarenhas, Luiz
author_role author
author2 LIma, Lorena
Pedra, Thaís
Assumpção, Adriana
Morgado, Sergio
Mascarenhas, Luiz
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Pinto, Gabryela
LIma, Lorena
Pedra, Thaís
Assumpção, Adriana
Morgado, Sergio
Mascarenhas, Luiz
dc.subject.other.pt_BR.fl_str_mv COVID-19
Coinfecção
Fungemia
Saccharomyces
Sepse
topic COVID-19
Coinfecção
Fungemia
Saccharomyces
Sepse
COVID-19
Coinfection
Fungaemia
Saccharomyces
Sepsis
dc.subject.en.en_US.fl_str_mv COVID-19
Coinfection
Fungaemia
Saccharomyces
Sepsis
description Hospital São Francisco de Assis. Comissão de Controle de Infecção Hospitalar. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2022-02-08T18:43:48Z
dc.date.available.fl_str_mv 2022-02-08T18:43:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv PINTO, Gabriela et al. Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil. Access Microbiology, v. 3, n. 8, p. 1-4, 6 Aug. 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/51093
dc.identifier.issn.pt_BR.fl_str_mv 2516-8290
dc.identifier.doi.none.fl_str_mv 10.1099/acmi.0.000250
dc.identifier.eissn.none.fl_str_mv 2516-8290
identifier_str_mv PINTO, Gabriela et al. Bloodstream infection by Saccharomyces cerevisiae in a COVID-19 patient receiving probiotic supplementation in the ICU in Brazil. Access Microbiology, v. 3, n. 8, p. 1-4, 6 Aug. 2021.
2516-8290
10.1099/acmi.0.000250
url https://www.arca.fiocruz.br/handle/icict/51093
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Microbiology Society
publisher.none.fl_str_mv Microbiology Society
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/51093/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/51093/2/Sergio_Morgado_etal_IOC_2021.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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