Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/22828 |
Resumo: | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Virologia e Terapia Experimental. Recife, PE, Brasil. |
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Santos, Jefferson José da SilvaMagalhães, TerezaSilva Junior, José Valter JoaquimSilva, Andréa Nazaré Monteiro Rangel daCordeiro, Marli TenórioGil, Laura Helena Vega Gonzales2017-10-13T12:01:09Z2017-10-13T12:01:09Z2015SANTOS, J. J. DA S. et al. Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil. Memorias Do Instituto Oswaldo Cruz, v. 110, n. 5, p. 677–683, ago. 2015.1678-8060https://www.arca.fiocruz.br/handle/icict/2282810.1590/0074-02760150053porVírus da DengueDNA ComplementarRNA ViralBrazilCloning, MolecularDengue VirusDNA, ComplementaryMolecular Sequence DataRNA, ViralSequence Analysis, DNAVirus ReplicationBrasilVírus da dengueDNA ComplementarRNA ViralClonagem molecularDados de Sequência MolecularReplicação ViralFull-length infectious clone of a low passage dengue virus serotype 2 from Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Virologia e Terapia Experimental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Virologia e Terapia Experimental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Virologia e Terapia Experimental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Virologia e Terapia Experimental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Virologia e Terapia Experimental. Recife, PE, Brasil / Departamento de Saúde do Estado de Pernambuco, Laboratório Central de Saúde Pública. Recife, PE, BrasilFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Virologia e Terapia Experimental. Recife, PE, Brasil.Full-length dengue virus (DENV) cDNA clones are an invaluable tool for many studies, including those on the development of attenuated or chimeric vaccines and on host-virus interactions. Furthermore, the importance of low passage DENV infectious clones should be highlighted, as these may harbour critical and unique strain-specific viral components from field-circulating isolates. The successful construction of a functional Brazilian low passage DENV serotype 2 full-length clone through homologous recombination reported here supports the use of a strategy that has been shown to be highly useful by our group for the development of flavivirus infectious clones and replicons.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/22828/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINAL26200712 2015 san-ful.oa.pdf26200712 2015 san-ful.oa.pdfapplication/pdf618253https://www.arca.fiocruz.br/bitstream/icict/22828/2/26200712%202015%20san-ful.oa.pdfe8ebe59f76093e9c30368300401fd675MD52TEXT26200712 2015 san-ful.oa.pdf.txt26200712 2015 san-ful.oa.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv |
Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil |
title |
Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil |
spellingShingle |
Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil Santos, Jefferson José da Silva Vírus da Dengue DNA Complementar RNA Viral Brazil Cloning, Molecular Dengue Virus DNA, Complementary Molecular Sequence Data RNA, Viral Sequence Analysis, DNA Virus Replication Brasil Vírus da dengue DNA Complementar RNA Viral Clonagem molecular Dados de Sequência Molecular Replicação Viral |
title_short |
Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil |
title_full |
Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil |
title_fullStr |
Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil |
title_full_unstemmed |
Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil |
title_sort |
Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil |
author |
Santos, Jefferson José da Silva |
author_facet |
Santos, Jefferson José da Silva Magalhães, Tereza Silva Junior, José Valter Joaquim Silva, Andréa Nazaré Monteiro Rangel da Cordeiro, Marli Tenório Gil, Laura Helena Vega Gonzales |
author_role |
author |
author2 |
Magalhães, Tereza Silva Junior, José Valter Joaquim Silva, Andréa Nazaré Monteiro Rangel da Cordeiro, Marli Tenório Gil, Laura Helena Vega Gonzales |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Santos, Jefferson José da Silva Magalhães, Tereza Silva Junior, José Valter Joaquim Silva, Andréa Nazaré Monteiro Rangel da Cordeiro, Marli Tenório Gil, Laura Helena Vega Gonzales |
dc.subject.other.pt_BR.fl_str_mv |
Vírus da Dengue DNA Complementar RNA Viral |
topic |
Vírus da Dengue DNA Complementar RNA Viral Brazil Cloning, Molecular Dengue Virus DNA, Complementary Molecular Sequence Data RNA, Viral Sequence Analysis, DNA Virus Replication Brasil Vírus da dengue DNA Complementar RNA Viral Clonagem molecular Dados de Sequência Molecular Replicação Viral |
dc.subject.en.pt_BR.fl_str_mv |
Brazil Cloning, Molecular Dengue Virus DNA, Complementary Molecular Sequence Data RNA, Viral Sequence Analysis, DNA Virus Replication |
dc.subject.decs.pt_BR.fl_str_mv |
Brasil Vírus da dengue DNA Complementar RNA Viral Clonagem molecular Dados de Sequência Molecular Replicação Viral |
description |
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Virologia e Terapia Experimental. Recife, PE, Brasil. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015 |
dc.date.accessioned.fl_str_mv |
2017-10-13T12:01:09Z |
dc.date.available.fl_str_mv |
2017-10-13T12:01:09Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SANTOS, J. J. DA S. et al. Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil. Memorias Do Instituto Oswaldo Cruz, v. 110, n. 5, p. 677–683, ago. 2015. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/22828 |
dc.identifier.issn.pt_BR.fl_str_mv |
1678-8060 |
dc.identifier.doi.none.fl_str_mv |
10.1590/0074-02760150053 |
identifier_str_mv |
SANTOS, J. J. DA S. et al. Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil. Memorias Do Instituto Oswaldo Cruz, v. 110, n. 5, p. 677–683, ago. 2015. 1678-8060 10.1590/0074-02760150053 |
url |
https://www.arca.fiocruz.br/handle/icict/22828 |
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por |
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