Cryptorchidism in Children with Zika-Related Microcephaly

Detalhes bibliográficos
Autor(a) principal: Vasconcelos, Rômulo A. L. de
Data de Publicação: 2020
Outros Autores: Ximenes, Ricardo A. A., Calado, Adriano A., Martelli, Celina M. T., Gonçalves, Andreia V., Brickley, Elizabeth B., Araújo, Thalia V. B. de, Rocha, Maria Angela Wanderley, Miranda-Filho, Demócrito de B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/47310
Resumo: Universidade de Pernambuco. Recife, PE, Brazil.
id CRUZ_8f03cbae7f1160e30c8adacb3e28e96a
oai_identifier_str oai:www.arca.fiocruz.br:icict/47310
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Vasconcelos, Rômulo A. L. deXimenes, Ricardo A. A.Calado, Adriano A.Martelli, Celina M. T.Gonçalves, Andreia V.Brickley, Elizabeth B.Araújo, Thalia V. B. deRocha, Maria Angela WanderleyMiranda-Filho, Demócrito de B.2021-05-24T13:37:36Z2021-05-24T13:37:36Z2020VASCONCELOS, Rômulo A. L. de et al. Cryptorchidism in Children with Zika-Related Microcephaly. The American Journal of Tropical Medicine and Hygiene, v. 102, n. 5, p. 982–984, May 2020.0002-9637https://www.arca.fiocruz.br/handle/icict/4731010.4269/ajtmh.19-07530002-9637BrazilChild PreschoolCryptorchidismHumansInfantInfant NewbornMaleMicrocephalyRick FactorsZika Virus InfectionBrazilChild PreschoolCryptorchidismHumansInfantInfant NewbornMaleMicrocephalyRick FactorsZika Virus InfectionBrasilPré-EscolarCriptorquidismoHumanosLactenteRecém-NascidoMasculinoMicrocefaliaFatores de RiscoInfecção por Zika virusCryptorchidism in Children with Zika-Related Microcephalyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade de Pernambuco. Recife, PE, Brazil.Universidade de Pernambuco. Recife, PE, Brazil.Universidade de Pernambuco. Recife, PE, Brazil.Fundação Oswaldo Cruz. Instituto de Pesquisa Aggeu Magalhães. Recife, PE, Brazil.Universidade Federal de Pernambuco. Recife, PE, Brazil.London School of Hygiene and Tropical Medicine. London, United Kingdom.Universidade Federal de Pernambuco. Recife, PE, Brazil.Universidade Federal de Pernambuco. Recife, PE, Brazil.The genitourinary tract was recently identified as a potential site of complications related to the congenital Zika syndrome (CZS). We provide the first report of a series of cryptorchidism cases in 3-year-old children with Zikarelated microcephaly who underwent consultations between October 2018 and April 2019 as part of the follow-up of the children cohort of the Microcephaly Epidemic Research Group, Pernambuco, Brazil. Of the 22 males examined, eight (36.4%) presented with cryptorchidism. Among 14 undescended testis cases, 11 (78.6%) could be palpated in the inguinal region. Seven of the eight children had severe microcephaly. Conventional risk factors for cryptorchidism were relatively infrequent in these children.Wehypothesize that cryptorchidism is an additional manifestation ofCZSpresent in children with severe microcephaly. As in our cases, for most of the children, the testes were located in the inguinal region, and the possible mechanisms for cryptorchidism were gubernaculum disturbance or cremasteric abnormality.info:eu-repo/semantics/openAccessengreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/47310/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALCryptorchidism in Children with Zika-Related Microcephaly.pdfCryptorchidism in Children with Zika-Related Microcephaly.pdfapplication/pdf59090https://www.arca.fiocruz.br/bitstream/icict/47310/2/Cryptorchidism%20in%20Children%20with%20Zika-Related%20Microcephaly.pdf3a81daa0a8823be42a2794fcc1cfd184MD52TEXTCryptorchidism in Children with Zika-Related Microcephaly.pdf.txtCryptorchidism in Children with Zika-Related Microcephaly.pdf.txtExtracted texttext/plain19025https://www.arca.fiocruz.br/bitstream/icict/47310/3/Cryptorchidism%20in%20Children%20with%20Zika-Related%20Microcephaly.pdf.txte2ca42e70a63e9bfe90fdf6c4a6cc5f6MD53icict/473102023-04-03 10:02:46.655oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-04-03T13:02:46Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Cryptorchidism in Children with Zika-Related Microcephaly
title Cryptorchidism in Children with Zika-Related Microcephaly
spellingShingle Cryptorchidism in Children with Zika-Related Microcephaly
Vasconcelos, Rômulo A. L. de
Brazil
Child Preschool
Cryptorchidism
Humans
Infant
Infant Newborn
Male
Microcephaly
Rick Factors
Zika Virus Infection
Brazil
Child Preschool
Cryptorchidism
Humans
Infant
Infant Newborn
Male
Microcephaly
Rick Factors
Zika Virus Infection
Brasil
Pré-Escolar
Criptorquidismo
Humanos
Lactente
Recém-Nascido
Masculino
Microcefalia
Fatores de Risco
Infecção por Zika virus
title_short Cryptorchidism in Children with Zika-Related Microcephaly
title_full Cryptorchidism in Children with Zika-Related Microcephaly
title_fullStr Cryptorchidism in Children with Zika-Related Microcephaly
title_full_unstemmed Cryptorchidism in Children with Zika-Related Microcephaly
title_sort Cryptorchidism in Children with Zika-Related Microcephaly
author Vasconcelos, Rômulo A. L. de
author_facet Vasconcelos, Rômulo A. L. de
Ximenes, Ricardo A. A.
Calado, Adriano A.
Martelli, Celina M. T.
Gonçalves, Andreia V.
Brickley, Elizabeth B.
Araújo, Thalia V. B. de
Rocha, Maria Angela Wanderley
Miranda-Filho, Demócrito de B.
author_role author
author2 Ximenes, Ricardo A. A.
Calado, Adriano A.
Martelli, Celina M. T.
Gonçalves, Andreia V.
Brickley, Elizabeth B.
Araújo, Thalia V. B. de
Rocha, Maria Angela Wanderley
Miranda-Filho, Demócrito de B.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Vasconcelos, Rômulo A. L. de
Ximenes, Ricardo A. A.
Calado, Adriano A.
Martelli, Celina M. T.
Gonçalves, Andreia V.
Brickley, Elizabeth B.
Araújo, Thalia V. B. de
Rocha, Maria Angela Wanderley
Miranda-Filho, Demócrito de B.
dc.subject.mesh.pt_BR.fl_str_mv Brazil
Child Preschool
Cryptorchidism
Humans
Infant
Infant Newborn
Male
Microcephaly
Rick Factors
Zika Virus Infection
topic Brazil
Child Preschool
Cryptorchidism
Humans
Infant
Infant Newborn
Male
Microcephaly
Rick Factors
Zika Virus Infection
Brazil
Child Preschool
Cryptorchidism
Humans
Infant
Infant Newborn
Male
Microcephaly
Rick Factors
Zika Virus Infection
Brasil
Pré-Escolar
Criptorquidismo
Humanos
Lactente
Recém-Nascido
Masculino
Microcefalia
Fatores de Risco
Infecção por Zika virus
dc.subject.en.pt_BR.fl_str_mv Brazil
Child Preschool
Cryptorchidism
Humans
Infant
Infant Newborn
Male
Microcephaly
Rick Factors
Zika Virus Infection
dc.subject.decs.pt_BR.fl_str_mv Brasil
Pré-Escolar
Criptorquidismo
Humanos
Lactente
Recém-Nascido
Masculino
Microcefalia
Fatores de Risco
Infecção por Zika virus
description Universidade de Pernambuco. Recife, PE, Brazil.
publishDate 2020
dc.date.issued.fl_str_mv 2020
dc.date.accessioned.fl_str_mv 2021-05-24T13:37:36Z
dc.date.available.fl_str_mv 2021-05-24T13:37:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv VASCONCELOS, Rômulo A. L. de et al. Cryptorchidism in Children with Zika-Related Microcephaly. The American Journal of Tropical Medicine and Hygiene, v. 102, n. 5, p. 982–984, May 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/47310
dc.identifier.issn.pt_BR.fl_str_mv 0002-9637
dc.identifier.doi.pt_BR.fl_str_mv 10.4269/ajtmh.19-0753
dc.identifier.eissn.none.fl_str_mv 0002-9637
identifier_str_mv VASCONCELOS, Rômulo A. L. de et al. Cryptorchidism in Children with Zika-Related Microcephaly. The American Journal of Tropical Medicine and Hygiene, v. 102, n. 5, p. 982–984, May 2020.
0002-9637
10.4269/ajtmh.19-0753
url https://www.arca.fiocruz.br/handle/icict/47310
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/47310/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/47310/2/Cryptorchidism%20in%20Children%20with%20Zika-Related%20Microcephaly.pdf
https://www.arca.fiocruz.br/bitstream/icict/47310/3/Cryptorchidism%20in%20Children%20with%20Zika-Related%20Microcephaly.pdf.txt
bitstream.checksum.fl_str_mv 5a560609d32a3863062d77ff32785d58
3a81daa0a8823be42a2794fcc1cfd184
e2ca42e70a63e9bfe90fdf6c4a6cc5f6
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813009294978711552