Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction

Detalhes bibliográficos
Autor(a) principal: Rocha, Isadora Filipaki Munhoz da
Data de Publicação: 2020
Outros Autores: Amatuzzi, Rafaela Ferreira, Lucena, Aline Castro Rodrigues, Faoro, Helisson, Alves, Lysangela Ronalte
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/45650
https://doaj.org/toc/2235-2988
Resumo: Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Regulação da Expressão Gênica. Curitiba, PR, Brasil.
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spelling Rocha, Isadora Filipaki Munhoz daAmatuzzi, Rafaela FerreiraLucena, Aline Castro RodriguesFaoro, HelissonAlves, Lysangela Ronalte2021-01-11T20:31:45Z2021-01-11T20:31:45Z2020ROCHA, Isadora Filipaki Munhoz da et al. Cross-Kingdom Extracelular Vesicles EV-RNA communication as a mechanism for host–pathogen interaction. Frontiers in Cellular and Infection Microbiology, v.10, n. 593160, p. 1–16, 2020.2235-2988https://www.arca.fiocruz.br/handle/icict/45650https://doaj.org/toc/2235-2988porFrontiers MediaCross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interactioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Regulação da Expressão Gênica. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Regulação da Expressão Gênica. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Ciências e Tecnologias Aplicadas em Saúde. Curitiba, PR, BrasilFundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Ciências e Tecnologias Aplicadas em Saúde. Curitiba, PR, BrasilFundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Regulação da Expressão Gênica. Curitiba, PR, Brasil.The extracellular vesicle (EVs) traffic has been highlighted as a very important pathway of cellular communication. EVs are produced by prokaryotes and eukaryotes organisms and can carry molecules to help maintain homeostasis, responding to general disbalance, infections, and allowing rapid modulation of the immune system. In the context of infection, EVs from both the host and the pathogen have been identified as playing roles in the recruitment of immunological molecules that can lead to the resolution of the infection or the host’s defeat. Bacterial vesicles RNA cargo play roles in the host cell by regulating gene expression and modulating immune response. In fungi the RNA molecules present in EVs are diverse and participate in communication between the host and pathogenic fungi. Little is known about how cross-kingdom sRNA trafficking occurs, although in recent years, there has been an increase in studies that relate EV participation in sRNA delivery. This review aims to elucidate and update the reader concerning the role of extracellular vesicles, with emphasis in the RNA content. We describe the EVs during infection from the host point-of-view, as well as the bacteria and fungi pathogens producing EVs that help the establishment of the disease.Extracellular VesiclesHost-Pathogen InteractionsBacteriaFungiInfectionsVesículas ExtracelularesInteracciones Huésped-PatógenoBacteriasHongosInfeccionesVésicules extracellulairesInteractions hôte-pathogèneBactériesFungusInfectionsVesículas ExtracelularesInterações Hospedeiro-PatógenoBactériasFungosInfecçõesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction
title Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction
spellingShingle Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction
Rocha, Isadora Filipaki Munhoz da
Extracellular Vesicles
Host-Pathogen Interactions
Bacteria
Fungi
Infections
Vesículas Extracelulares
Interacciones Huésped-Patógeno
Bacterias
Hongos
Infecciones
Vésicules extracellulaires
Interactions hôte-pathogène
Bactéries
Fungus
Infections
Vesículas Extracelulares
Interações Hospedeiro-Patógeno
Bactérias
Fungos
Infecções
title_short Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction
title_full Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction
title_fullStr Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction
title_full_unstemmed Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction
title_sort Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction
author Rocha, Isadora Filipaki Munhoz da
author_facet Rocha, Isadora Filipaki Munhoz da
Amatuzzi, Rafaela Ferreira
Lucena, Aline Castro Rodrigues
Faoro, Helisson
Alves, Lysangela Ronalte
author_role author
author2 Amatuzzi, Rafaela Ferreira
Lucena, Aline Castro Rodrigues
Faoro, Helisson
Alves, Lysangela Ronalte
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Rocha, Isadora Filipaki Munhoz da
Amatuzzi, Rafaela Ferreira
Lucena, Aline Castro Rodrigues
Faoro, Helisson
Alves, Lysangela Ronalte
dc.subject.en.pt_BR.fl_str_mv Extracellular Vesicles
Host-Pathogen Interactions
Bacteria
Fungi
Infections
topic Extracellular Vesicles
Host-Pathogen Interactions
Bacteria
Fungi
Infections
Vesículas Extracelulares
Interacciones Huésped-Patógeno
Bacterias
Hongos
Infecciones
Vésicules extracellulaires
Interactions hôte-pathogène
Bactéries
Fungus
Infections
Vesículas Extracelulares
Interações Hospedeiro-Patógeno
Bactérias
Fungos
Infecções
dc.subject.es.pt_BR.fl_str_mv Vesículas Extracelulares
Interacciones Huésped-Patógeno
Bacterias
Hongos
Infecciones
dc.subject.fr.pt_BR.fl_str_mv Vésicules extracellulaires
Interactions hôte-pathogène
Bactéries
Fungus
Infections
dc.subject.decs.pt_BR.fl_str_mv Vesículas Extracelulares
Interações Hospedeiro-Patógeno
Bactérias
Fungos
Infecções
description Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Regulação da Expressão Gênica. Curitiba, PR, Brasil.
publishDate 2020
dc.date.issued.fl_str_mv 2020
dc.date.accessioned.fl_str_mv 2021-01-11T20:31:45Z
dc.date.available.fl_str_mv 2021-01-11T20:31:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ROCHA, Isadora Filipaki Munhoz da et al. Cross-Kingdom Extracelular Vesicles EV-RNA communication as a mechanism for host–pathogen interaction. Frontiers in Cellular and Infection Microbiology, v.10, n. 593160, p. 1–16, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/45650
dc.identifier.issn.pt_BR.fl_str_mv 2235-2988
dc.identifier.doi.none.fl_str_mv https://doaj.org/toc/2235-2988
identifier_str_mv ROCHA, Isadora Filipaki Munhoz da et al. Cross-Kingdom Extracelular Vesicles EV-RNA communication as a mechanism for host–pathogen interaction. Frontiers in Cellular and Infection Microbiology, v.10, n. 593160, p. 1–16, 2020.
2235-2988
url https://www.arca.fiocruz.br/handle/icict/45650
https://doaj.org/toc/2235-2988
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/45650/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/45650/2/fcimb-10-593160.pdf
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