Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/45650 https://doaj.org/toc/2235-2988 |
Resumo: | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Regulação da Expressão Gênica. Curitiba, PR, Brasil. |
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Rocha, Isadora Filipaki Munhoz daAmatuzzi, Rafaela FerreiraLucena, Aline Castro RodriguesFaoro, HelissonAlves, Lysangela Ronalte2021-01-11T20:31:45Z2021-01-11T20:31:45Z2020ROCHA, Isadora Filipaki Munhoz da et al. Cross-Kingdom Extracelular Vesicles EV-RNA communication as a mechanism for host–pathogen interaction. Frontiers in Cellular and Infection Microbiology, v.10, n. 593160, p. 1–16, 2020.2235-2988https://www.arca.fiocruz.br/handle/icict/45650https://doaj.org/toc/2235-2988porFrontiers MediaCross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interactioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Regulação da Expressão Gênica. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Regulação da Expressão Gênica. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Ciências e Tecnologias Aplicadas em Saúde. Curitiba, PR, BrasilFundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Ciências e Tecnologias Aplicadas em Saúde. Curitiba, PR, BrasilFundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Regulação da Expressão Gênica. Curitiba, PR, Brasil.The extracellular vesicle (EVs) traffic has been highlighted as a very important pathway of cellular communication. EVs are produced by prokaryotes and eukaryotes organisms and can carry molecules to help maintain homeostasis, responding to general disbalance, infections, and allowing rapid modulation of the immune system. In the context of infection, EVs from both the host and the pathogen have been identified as playing roles in the recruitment of immunological molecules that can lead to the resolution of the infection or the host’s defeat. Bacterial vesicles RNA cargo play roles in the host cell by regulating gene expression and modulating immune response. In fungi the RNA molecules present in EVs are diverse and participate in communication between the host and pathogenic fungi. Little is known about how cross-kingdom sRNA trafficking occurs, although in recent years, there has been an increase in studies that relate EV participation in sRNA delivery. This review aims to elucidate and update the reader concerning the role of extracellular vesicles, with emphasis in the RNA content. We describe the EVs during infection from the host point-of-view, as well as the bacteria and fungi pathogens producing EVs that help the establishment of the disease.Extracellular VesiclesHost-Pathogen InteractionsBacteriaFungiInfectionsVesículas ExtracelularesInteracciones Huésped-PatógenoBacteriasHongosInfeccionesVésicules extracellulairesInteractions hôte-pathogèneBactériesFungusInfectionsVesículas ExtracelularesInterações Hospedeiro-PatógenoBactériasFungosInfecçõesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv |
Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction |
title |
Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction |
spellingShingle |
Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction Rocha, Isadora Filipaki Munhoz da Extracellular Vesicles Host-Pathogen Interactions Bacteria Fungi Infections Vesículas Extracelulares Interacciones Huésped-Patógeno Bacterias Hongos Infecciones Vésicules extracellulaires Interactions hôte-pathogène Bactéries Fungus Infections Vesículas Extracelulares Interações Hospedeiro-Patógeno Bactérias Fungos Infecções |
title_short |
Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction |
title_full |
Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction |
title_fullStr |
Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction |
title_full_unstemmed |
Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction |
title_sort |
Cross-kingdom extracellular vesicles EV-RNA communication as a mechanism for host–pathogen interaction |
author |
Rocha, Isadora Filipaki Munhoz da |
author_facet |
Rocha, Isadora Filipaki Munhoz da Amatuzzi, Rafaela Ferreira Lucena, Aline Castro Rodrigues Faoro, Helisson Alves, Lysangela Ronalte |
author_role |
author |
author2 |
Amatuzzi, Rafaela Ferreira Lucena, Aline Castro Rodrigues Faoro, Helisson Alves, Lysangela Ronalte |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Rocha, Isadora Filipaki Munhoz da Amatuzzi, Rafaela Ferreira Lucena, Aline Castro Rodrigues Faoro, Helisson Alves, Lysangela Ronalte |
dc.subject.en.pt_BR.fl_str_mv |
Extracellular Vesicles Host-Pathogen Interactions Bacteria Fungi Infections |
topic |
Extracellular Vesicles Host-Pathogen Interactions Bacteria Fungi Infections Vesículas Extracelulares Interacciones Huésped-Patógeno Bacterias Hongos Infecciones Vésicules extracellulaires Interactions hôte-pathogène Bactéries Fungus Infections Vesículas Extracelulares Interações Hospedeiro-Patógeno Bactérias Fungos Infecções |
dc.subject.es.pt_BR.fl_str_mv |
Vesículas Extracelulares Interacciones Huésped-Patógeno Bacterias Hongos Infecciones |
dc.subject.fr.pt_BR.fl_str_mv |
Vésicules extracellulaires Interactions hôte-pathogène Bactéries Fungus Infections |
dc.subject.decs.pt_BR.fl_str_mv |
Vesículas Extracelulares Interações Hospedeiro-Patógeno Bactérias Fungos Infecções |
description |
Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Regulação da Expressão Gênica. Curitiba, PR, Brasil. |
publishDate |
2020 |
dc.date.issued.fl_str_mv |
2020 |
dc.date.accessioned.fl_str_mv |
2021-01-11T20:31:45Z |
dc.date.available.fl_str_mv |
2021-01-11T20:31:45Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
ROCHA, Isadora Filipaki Munhoz da et al. Cross-Kingdom Extracelular Vesicles EV-RNA communication as a mechanism for host–pathogen interaction. Frontiers in Cellular and Infection Microbiology, v.10, n. 593160, p. 1–16, 2020. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/45650 |
dc.identifier.issn.pt_BR.fl_str_mv |
2235-2988 |
dc.identifier.doi.none.fl_str_mv |
https://doaj.org/toc/2235-2988 |
identifier_str_mv |
ROCHA, Isadora Filipaki Munhoz da et al. Cross-Kingdom Extracelular Vesicles EV-RNA communication as a mechanism for host–pathogen interaction. Frontiers in Cellular and Infection Microbiology, v.10, n. 593160, p. 1–16, 2020. 2235-2988 |
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https://www.arca.fiocruz.br/handle/icict/45650 https://doaj.org/toc/2235-2988 |
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Frontiers Media |
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Frontiers Media |
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