Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2014 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/23265 |
Resumo: | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil. |
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Martins, Albert Eduardo SilvaLucena-Silva, NormaGarcia, Renan GomesWelkovic, StefanBarboza, AurelianaMenezes, Maria Luiza BezerraMaruza, MagdaTenório, TerezinhaXimenes, Ricardo A. A.2017-11-20T11:50:55Z2017-11-20T11:50:55Z2014MARTINS, A. E. S. et al. Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 109, n. 6, p. 738–747, set. 2014.1678-8060https://www.arca.fiocruz.br/handle/icict/2326510.1590/0074-0276140070engFatores de Riscoprevalência de HPVCo-infecção por HIV-HPVTipos de HPVHPV prevalenceHPV typing distributionHIV-HPV coinfectionrisk factorsHPV typesSíndrome de Imunodeficiência AdquiridavirologiaColo do ÚterovirologiaSoroprevalência de HIVConsumo de Bebidas AlcoólicasPapillomaviridaeclassificaçãoInfecções por PapillomavirusepidemiologiaHIVimunologiaInquéritos e QuestionáriosCentros de Atenção TerciáriaContagem de Linfócito CD4HumanosRendaFemininoBrasilepidemiologiaPrevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Imunogenética. Recife, PE, Brasil / Instituto de Medicina Integral Professor Fernando Figueira. Hospital de Ensino. Departamento de Oncologia Pediátrica. Laboratório de Biologia Molecular. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Imunogenética. Recife, PE, Brasil / Instituto de Medicina Integral Professor Fernando Figueira. Hospital de Ensino. Departamento de Oncologia Pediátrica. Laboratório de Biologia Molecular. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Imunogenética. Recife, PE, Brasil.Centro Integrado de Saúde Amaury de Medeiros. Disciplina de Obstetrícia e Ginecologia. Recife, PE, Brasil.Universidade de Pernambuco. Faculdade de Ciências Médicas. Departamento Materno-Infantil. Recife, PE, Brasil.Universidade de Pernambuco. Faculdade de Ciências Médicas. Departamento Materno-Infantil. Recife, PE, Brasil.Secretaria de Saúde de Pernambuco. Hospital Correia Picanço. Recife, PE, Brasil.Universidade Federal de Pernambuco. Departamento Materno-Infantil. Recife, PE, Brasil.Universidade Federal de Pernambuco. Departamento de Medicina Tropical. Recife, PE, Brasil.Human immunodeficiency virus (HIV)-positive patients have a greater prevalence of coinfection with human papillomavirus (HPV) is of high oncogenic risk. Indeed, the presence of the virus favours intraepithelial squamous cell lesion progression and may induce cancer. The aim of this study was to evaluate the prevalence of HPV infection, distribution of HPV types and risk factors among HIV-positive patients. Cervical samples from 450 HIV-positive patients were analysed with regard to oncotic cytology, colposcopy and HPV presence and type by means of polymerase chain reaction and sequencing. The results were analysed by comparing demographic data and data relating to HPV and HIV infection. The prevalence of HPV was 47.5%. Among the HPV-positive samples, 59% included viral types of high oncogenic risk. Multivariate analysis showed an association between HPV infection and the presence of cytological alterations (p = 0.003), age greater than or equal to 35 years (p = 0.002), number of partners greater than three (p = 0.002), CD4⁺ lymphocyte count < 200/mm³ (p = 0.041) and alcohol abuse (p = 0.004). Although high-risk HPV was present in the majority of the lesions studied, the low frequency of HPV 16 (3.3%), low occurrence of cervical lesions and preserved immunological state in most of the HIV-positive patients were factors that may explain the low occurrence of precancerous cervical lesions in this population.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83092https://www.arca.fiocruz.br/bitstream/icict/23265/1/license.txt447f2497af1ef5cf99b5c07f6fa18dceMD51ORIGINALart. Prevalence of human - martins.pdfart. Prevalence of human - martins.pdfapplication/pdf441033https://www.arca.fiocruz.br/bitstream/icict/23265/2/art.%20Prevalence%20of%20human%20-%20martins.pdfdcf9ad8a55642171d48a225f604d1045MD52TEXTart. Prevalence of human - martins.pdf.txtart. 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| dc.title.pt_BR.fl_str_mv |
Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil |
| title |
Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil |
| spellingShingle |
Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil Martins, Albert Eduardo Silva Fatores de Risco prevalência de HPV Co-infecção por HIV-HPV Tipos de HPV HPV prevalence HPV typing distribution HIV-HPV coinfection risk factors HPV types Síndrome de Imunodeficiência Adquirida virologia Colo do Útero virologia Soroprevalência de HIV Consumo de Bebidas Alcoólicas Papillomaviridae classificação Infecções por Papillomavirus epidemiologia HIV imunologia Inquéritos e Questionários Centros de Atenção Terciária Contagem de Linfócito CD4 Humanos Renda Feminino Brasil epidemiologia |
| title_short |
Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil |
| title_full |
Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil |
| title_fullStr |
Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil |
| title_full_unstemmed |
Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil |
| title_sort |
Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil |
| author |
Martins, Albert Eduardo Silva |
| author_facet |
Martins, Albert Eduardo Silva Lucena-Silva, Norma Garcia, Renan Gomes Welkovic, Stefan Barboza, Aureliana Menezes, Maria Luiza Bezerra Maruza, Magda Tenório, Terezinha Ximenes, Ricardo A. A. |
| author_role |
author |
| author2 |
Lucena-Silva, Norma Garcia, Renan Gomes Welkovic, Stefan Barboza, Aureliana Menezes, Maria Luiza Bezerra Maruza, Magda Tenório, Terezinha Ximenes, Ricardo A. A. |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Martins, Albert Eduardo Silva Lucena-Silva, Norma Garcia, Renan Gomes Welkovic, Stefan Barboza, Aureliana Menezes, Maria Luiza Bezerra Maruza, Magda Tenório, Terezinha Ximenes, Ricardo A. A. |
| dc.subject.other.pt_BR.fl_str_mv |
Fatores de Risco prevalência de HPV Co-infecção por HIV-HPV Tipos de HPV |
| topic |
Fatores de Risco prevalência de HPV Co-infecção por HIV-HPV Tipos de HPV HPV prevalence HPV typing distribution HIV-HPV coinfection risk factors HPV types Síndrome de Imunodeficiência Adquirida virologia Colo do Útero virologia Soroprevalência de HIV Consumo de Bebidas Alcoólicas Papillomaviridae classificação Infecções por Papillomavirus epidemiologia HIV imunologia Inquéritos e Questionários Centros de Atenção Terciária Contagem de Linfócito CD4 Humanos Renda Feminino Brasil epidemiologia |
| dc.subject.en.pt_BR.fl_str_mv |
HPV prevalence HPV typing distribution HIV-HPV coinfection risk factors HPV types |
| dc.subject.decs.pt_BR.fl_str_mv |
Síndrome de Imunodeficiência Adquirida virologia Colo do Útero virologia Soroprevalência de HIV Consumo de Bebidas Alcoólicas Papillomaviridae classificação Infecções por Papillomavirus epidemiologia HIV imunologia Inquéritos e Questionários Centros de Atenção Terciária Contagem de Linfócito CD4 Humanos Renda Feminino Brasil epidemiologia |
| description |
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil. |
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2014 |
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2014 |
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2017-11-20T11:50:55Z |
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2017-11-20T11:50:55Z |
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MARTINS, A. E. S. et al. Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 109, n. 6, p. 738–747, set. 2014. |
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https://www.arca.fiocruz.br/handle/icict/23265 |
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1678-8060 |
| dc.identifier.doi.none.fl_str_mv |
10.1590/0074-0276140070 |
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MARTINS, A. E. S. et al. Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 109, n. 6, p. 738–747, set. 2014. 1678-8060 10.1590/0074-0276140070 |
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https://www.arca.fiocruz.br/handle/icict/23265 |
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