Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil

Detalhes bibliográficos
Autor(a) principal: Martins, Albert Eduardo Silva
Data de Publicação: 2014
Outros Autores: Lucena-Silva, Norma, Garcia, Renan Gomes, Welkovic, Stefan, Barboza, Aureliana, Menezes, Maria Luiza Bezerra, Maruza, Magda, Tenório, Terezinha, Ximenes, Ricardo A. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/23265
Resumo: Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
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spelling Martins, Albert Eduardo SilvaLucena-Silva, NormaGarcia, Renan GomesWelkovic, StefanBarboza, AurelianaMenezes, Maria Luiza BezerraMaruza, MagdaTenório, TerezinhaXimenes, Ricardo A. A.2017-11-20T11:50:55Z2017-11-20T11:50:55Z2014MARTINS, A. E. S. et al. Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 109, n. 6, p. 738–747, set. 2014.1678-8060https://www.arca.fiocruz.br/handle/icict/2326510.1590/0074-0276140070engFatores de Riscoprevalência de HPVCo-infecção por HIV-HPVTipos de HPVHPV prevalenceHPV typing distributionHIV-HPV coinfectionrisk factorsHPV typesSíndrome de Imunodeficiência AdquiridavirologiaColo do ÚterovirologiaSoroprevalência de HIVConsumo de Bebidas AlcoólicasPapillomaviridaeclassificaçãoInfecções por PapillomavirusepidemiologiaHIVimunologiaInquéritos e QuestionáriosCentros de Atenção TerciáriaContagem de Linfócito CD4HumanosRendaFemininoBrasilepidemiologiaPrevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Imunogenética. Recife, PE, Brasil / Instituto de Medicina Integral Professor Fernando Figueira. Hospital de Ensino. Departamento de Oncologia Pediátrica. Laboratório de Biologia Molecular. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Imunogenética. Recife, PE, Brasil / Instituto de Medicina Integral Professor Fernando Figueira. Hospital de Ensino. Departamento de Oncologia Pediátrica. Laboratório de Biologia Molecular. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Laboratório de Imunogenética. Recife, PE, Brasil.Centro Integrado de Saúde Amaury de Medeiros. Disciplina de Obstetrícia e Ginecologia. Recife, PE, Brasil.Universidade de Pernambuco. Faculdade de Ciências Médicas. Departamento Materno-Infantil. Recife, PE, Brasil.Universidade de Pernambuco. Faculdade de Ciências Médicas. Departamento Materno-Infantil. Recife, PE, Brasil.Secretaria de Saúde de Pernambuco. Hospital Correia Picanço. Recife, PE, Brasil.Universidade Federal de Pernambuco. Departamento Materno-Infantil. Recife, PE, Brasil.Universidade Federal de Pernambuco. Departamento de Medicina Tropical. Recife, PE, Brasil.Human immunodeficiency virus (HIV)-positive patients have a greater prevalence of coinfection with human papillomavirus (HPV) is of high oncogenic risk. Indeed, the presence of the virus favours intraepithelial squamous cell lesion progression and may induce cancer. The aim of this study was to evaluate the prevalence of HPV infection, distribution of HPV types and risk factors among HIV-positive patients. Cervical samples from 450 HIV-positive patients were analysed with regard to oncotic cytology, colposcopy and HPV presence and type by means of polymerase chain reaction and sequencing. The results were analysed by comparing demographic data and data relating to HPV and HIV infection. The prevalence of HPV was 47.5%. Among the HPV-positive samples, 59% included viral types of high oncogenic risk. Multivariate analysis showed an association between HPV infection and the presence of cytological alterations (p = 0.003), age greater than or equal to 35 years (p = 0.002), number of partners greater than three (p = 0.002), CD4⁺ lymphocyte count < 200/mm³ (p = 0.041) and alcohol abuse (p = 0.004). Although high-risk HPV was present in the majority of the lesions studied, the low frequency of HPV 16 (3.3%), low occurrence of cervical lesions and preserved immunological state in most of the HIV-positive patients were factors that may explain the low occurrence of precancerous cervical lesions in this population.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83092https://www.arca.fiocruz.br/bitstream/icict/23265/1/license.txt447f2497af1ef5cf99b5c07f6fa18dceMD51ORIGINALart. Prevalence of human - martins.pdfart. Prevalence of human - martins.pdfapplication/pdf441033https://www.arca.fiocruz.br/bitstream/icict/23265/2/art.%20Prevalence%20of%20human%20-%20martins.pdfdcf9ad8a55642171d48a225f604d1045MD52TEXTart. Prevalence of human - martins.pdf.txtart. 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dc.title.pt_BR.fl_str_mv Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil
title Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil
spellingShingle Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil
Martins, Albert Eduardo Silva
Fatores de Risco
prevalência de HPV
Co-infecção por HIV-HPV
Tipos de HPV
HPV prevalence
HPV typing distribution
HIV-HPV coinfection
risk factors
HPV types
Síndrome de Imunodeficiência Adquirida
virologia
Colo do Útero
virologia
Soroprevalência de HIV
Consumo de Bebidas Alcoólicas
Papillomaviridae
classificação
Infecções por Papillomavirus
epidemiologia
HIV
imunologia
Inquéritos e Questionários
Centros de Atenção Terciária
Contagem de Linfócito CD4
Humanos
Renda
Feminino
Brasil
epidemiologia
title_short Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil
title_full Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil
title_fullStr Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil
title_full_unstemmed Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil
title_sort Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil
author Martins, Albert Eduardo Silva
author_facet Martins, Albert Eduardo Silva
Lucena-Silva, Norma
Garcia, Renan Gomes
Welkovic, Stefan
Barboza, Aureliana
Menezes, Maria Luiza Bezerra
Maruza, Magda
Tenório, Terezinha
Ximenes, Ricardo A. A.
author_role author
author2 Lucena-Silva, Norma
Garcia, Renan Gomes
Welkovic, Stefan
Barboza, Aureliana
Menezes, Maria Luiza Bezerra
Maruza, Magda
Tenório, Terezinha
Ximenes, Ricardo A. A.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Martins, Albert Eduardo Silva
Lucena-Silva, Norma
Garcia, Renan Gomes
Welkovic, Stefan
Barboza, Aureliana
Menezes, Maria Luiza Bezerra
Maruza, Magda
Tenório, Terezinha
Ximenes, Ricardo A. A.
dc.subject.other.pt_BR.fl_str_mv Fatores de Risco
prevalência de HPV
Co-infecção por HIV-HPV
Tipos de HPV
topic Fatores de Risco
prevalência de HPV
Co-infecção por HIV-HPV
Tipos de HPV
HPV prevalence
HPV typing distribution
HIV-HPV coinfection
risk factors
HPV types
Síndrome de Imunodeficiência Adquirida
virologia
Colo do Útero
virologia
Soroprevalência de HIV
Consumo de Bebidas Alcoólicas
Papillomaviridae
classificação
Infecções por Papillomavirus
epidemiologia
HIV
imunologia
Inquéritos e Questionários
Centros de Atenção Terciária
Contagem de Linfócito CD4
Humanos
Renda
Feminino
Brasil
epidemiologia
dc.subject.en.pt_BR.fl_str_mv HPV prevalence
HPV typing distribution
HIV-HPV coinfection
risk factors
HPV types
dc.subject.decs.pt_BR.fl_str_mv Síndrome de Imunodeficiência Adquirida
virologia
Colo do Útero
virologia
Soroprevalência de HIV
Consumo de Bebidas Alcoólicas
Papillomaviridae
classificação
Infecções por Papillomavirus
epidemiologia
HIV
imunologia
Inquéritos e Questionários
Centros de Atenção Terciária
Contagem de Linfócito CD4
Humanos
Renda
Feminino
Brasil
epidemiologia
description Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2017-11-20T11:50:55Z
dc.date.available.fl_str_mv 2017-11-20T11:50:55Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MARTINS, A. E. S. et al. Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 109, n. 6, p. 738–747, set. 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/23265
dc.identifier.issn.pt_BR.fl_str_mv 1678-8060
dc.identifier.doi.none.fl_str_mv 10.1590/0074-0276140070
identifier_str_mv MARTINS, A. E. S. et al. Prevalence of human papillomavirus infection, distribution of viral types and risk factors in cervical samples from human immunodeficiency virus-positive women attending three human immunodeficiency virus-acquired immune deficiency syndrome reference centres in northeastern Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 109, n. 6, p. 738–747, set. 2014.
1678-8060
10.1590/0074-0276140070
url https://www.arca.fiocruz.br/handle/icict/23265
dc.language.iso.fl_str_mv eng
language eng
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institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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