Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities

Detalhes bibliográficos
Autor(a) principal: Simões, Rachel Siqueira de Queiroz
Data de Publicação: 2018
Outros Autores: Silva, Emmanuele Pariz, Barth, Ortrud Monika
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/29342
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ. Brasil.
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spelling Simões, Rachel Siqueira de QueirozSilva, Emmanuele ParizBarth, Ortrud Monika2018-10-04T15:29:13Z2018-10-04T15:29:13Z2018SIMÕES, Rachel Siqueira de Queiroz; SILVA, Emmanuele Pariz; BARTH, Ortrud Monika. Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities. Advances in Biotechnology & Microbiology, v.8, n.5, 7p, Mar. 2018.2474-7637https://www.arca.fiocruz.br/handle/icict/2934210.19080/AIBM.2018.08.555749engJuniper PublishersNeoplasias do Colo do ÚteroEpidemiologiaPapillomaviridaeprevalênciaFatores preditoresCervical cancerEpidemiologyHuman papillomavirusPredictor factorsPrevalencePrevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalitiesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ. Brasil.Universidade Itajaí. Vale do Itajaí, SC, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ. Brasil.HPV is the most common sexually transmitted disease based on its oncogenic activity as high-risk (hr) types, low-risk types (lr) and types of undetermined-risk depending upon the associated diseases. The aim of this study was to evaluate the HPV infection prevalence and to identify the risk factors as demographic, behavioral and biological variables related to cervical cancer in unimmunized and sexually active women patients attended at public health institutions. A cross-sectional study conducted from 2014 to 2016 was performed at Rio de Janeiro city. All women were randomly selected and submitted to clinical and sociodemographic investigation. About 100 cervical cell scrapings were collected with a cervical cytobrush during the gynecological examination. After nucleic acid amplification directed to a conserved region of the HPV L1 gene, high-risk type specific primers (HPV16/18/31/45) were performed for genotyping. Statistical analysis was applied to analyze the risk factors associated with HPV infection in 18 sociodemographics variables obtained from informative questionnaires. This study demonstrated by the Chi-square test that of the 100 participants, 20% (95% CI: 12-28) were DNA HPV positive. HPV 18 and 45 were the most frequently detected HPV types. Most women were currently not married (56%) and married or cohabitating (44%) (p<0.05). Psychosocial and psychosexual issues demonstrated that six percent of the women exhibit history of sexually transmitted diseases, except HIV, with 85% of women having sex with until to five partners (p<0.03) and 15% used oral contraceptives, while 71% did not use any type of condom (p<0.03). A previous history of STD was not significantly related. Cytological status was without alterations in the population investigated. This paper contributed to a better understanding about the natural history of HPV from of the pre-immunization prevalence study of the active sexually and clinical free lesions women in Brazil.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/29342/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALortrudmonika_barth_etal_IOC_2018.pdfortrudmonika_barth_etal_IOC_2018.pdfapplication/pdf693758https://www.arca.fiocruz.br/bitstream/icict/29342/2/ortrudmonika_barth_etal_IOC_2018.pdf220f695fa564a05da6ebb744e50b8dc3MD52TEXTortrudmonika_barth_etal_IOC_2018.pdf.txtortrudmonika_barth_etal_IOC_2018.pdf.txtExtracted texttext/plain26832https://www.arca.fiocruz.br/bitstream/icict/29342/3/ortrudmonika_barth_etal_IOC_2018.pdf.txtaff7e57d8af05605c902a634e6b97c6eMD53icict/293422018-10-05 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dc.title.pt_BR.fl_str_mv Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities
title Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities
spellingShingle Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities
Simões, Rachel Siqueira de Queiroz
Neoplasias do Colo do Útero
Epidemiologia
Papillomaviridae
prevalência
Fatores preditores
Cervical cancer
Epidemiology
Human papillomavirus
Predictor factors
Prevalence
title_short Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities
title_full Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities
title_fullStr Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities
title_full_unstemmed Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities
title_sort Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities
author Simões, Rachel Siqueira de Queiroz
author_facet Simões, Rachel Siqueira de Queiroz
Silva, Emmanuele Pariz
Barth, Ortrud Monika
author_role author
author2 Silva, Emmanuele Pariz
Barth, Ortrud Monika
author2_role author
author
dc.contributor.author.fl_str_mv Simões, Rachel Siqueira de Queiroz
Silva, Emmanuele Pariz
Barth, Ortrud Monika
dc.subject.other.pt_BR.fl_str_mv Neoplasias do Colo do Útero
Epidemiologia
Papillomaviridae
prevalência
Fatores preditores
topic Neoplasias do Colo do Útero
Epidemiologia
Papillomaviridae
prevalência
Fatores preditores
Cervical cancer
Epidemiology
Human papillomavirus
Predictor factors
Prevalence
dc.subject.en.pt_BR.fl_str_mv Cervical cancer
Epidemiology
Human papillomavirus
Predictor factors
Prevalence
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ. Brasil.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-10-04T15:29:13Z
dc.date.available.fl_str_mv 2018-10-04T15:29:13Z
dc.date.issued.fl_str_mv 2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SIMÕES, Rachel Siqueira de Queiroz; SILVA, Emmanuele Pariz; BARTH, Ortrud Monika. Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities. Advances in Biotechnology & Microbiology, v.8, n.5, 7p, Mar. 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/29342
dc.identifier.issn.pt_BR.fl_str_mv 2474-7637
dc.identifier.doi.none.fl_str_mv 10.19080/AIBM.2018.08.555749
identifier_str_mv SIMÕES, Rachel Siqueira de Queiroz; SILVA, Emmanuele Pariz; BARTH, Ortrud Monika. Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities. Advances in Biotechnology & Microbiology, v.8, n.5, 7p, Mar. 2018.
2474-7637
10.19080/AIBM.2018.08.555749
url https://www.arca.fiocruz.br/handle/icict/29342
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Juniper Publishers
publisher.none.fl_str_mv Juniper Publishers
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/29342/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/29342/2/ortrudmonika_barth_etal_IOC_2018.pdf
https://www.arca.fiocruz.br/bitstream/icict/29342/3/ortrudmonika_barth_etal_IOC_2018.pdf.txt
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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